Results 31 to 40 of about 12,887 (114)

Immune complexes in chronic Chagas disease patients are formed by exovesicles from Trypanosoma cruzi carrying the conserved MASP N-terminal region [PDF]

, 2017
The exovesicles (EVs) are involved in pathologic host-parasite immune associations and have been recently used as biomarkers for diagnosis of infectious diseases.
De Pablos, Luis Miguel, Díaz Lozano, Isabel María, Longhi, Silvia Andrea, Osuna, Antonio, Schijman, Alejandro Gabriel, Zago, María Paola   +5 more
core   +3 more sources

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Highly syntenic and yet divergent: a tale of two Theilerias [PDF]

, 2009
The published genomic sequences of the two major host-transforming Theileria species of cattle represent a rich resource of information that has allowed novel bioinformatic and experimental studies into these important apicomplexan parasites. Since their
Bishop, R., Chaussepied, M., de Villiers, E.P., Langsley, G., Shiels, B., Skilton, R., Sunter, J., Tait, A., Weir, W.   +8 more
core   +1 more source

Structural and Functional Characterization of the 28 kDa Structured Core of BmSA1, the Major Surface Antigen of Babesia Microti

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Babesiosis is a tick‐borne disease that poses a significant threat to animal health worldwide. In addition, climate change and the risk of human‐to‐human transmission through blood transfusion have made babesiosis an emerging disease in humans.
Assia Mouhand, Joana Pissarra, Philippe Barthe, Christian Roumestand, Stéphane Delbecq   +4 more
wiley   +1 more source

Antigenicity of cystatin-binding proteins from parasitic protozoan Detection by a proteinase inhibitor based capture immunoassay (PINC-ELISA) [PDF]

Journal of Immunological Methods, 1995
A novel immunoassay (PINC-ELISA) was designed using proteinase inhibitors of the cystatin superfamily (PINC) in the solid phase, to promote the selective capture of cysteine proteinases. The method was applied in the identification of papain-like antigens from parasitic protozoa. PINC of human origin, namely recombinant cystatin C (r-cystatin C) or low
I V Silva, Aldina Barral, C B de Souza, Magnus Abrahamson, Julio Scharfstein   +4 more
openaire   +3 more sources

Molecular and antigenic characterization of Trypanosoma cruzi TolT proteins [PDF]

, 2018
Background: TolT was originally described as a Trypanosoma cruzi molecule that accumulated on the trypomastigote flagellum bearing similarity to bacterial TolA colicins receptors.
Agüero, Fernan Gonzalo, Altcheh, Jaime Marcelo, Balouz, Virginia, Buscaglia, Carlos Andres, Camara, María de los Milagros, Campetella, Oscar Eduardo, Canepa, Gaspar Exequiel, Carlevaro, Giannina Alejandra, Carmona, Santiago Javier, Ciocchini, Andres Eduardo, Cortina, María Eugenia, Lobo, Mabel Maite, Melli, Luciano Jorge, Mucci, Juan Sebastián   +13 more
core   +1 more source

Expression, characterisation and antigenicity of a truncated Hendra virus attachment protein expressed in the protozoan host Leishmania tarentolae

Journal of Virological Methods, 2016
Hendra virus (HeV) is an emerging zoonotic paramyxovirus within the genus Henipavirus that has caused severe morbidity and mortality in humans and horses in Australia since 1994. HeV infection of host cells is mediated by the membrane bound attachment (G) and fusion (F) glycoproteins, that are essential for receptor binding and fusion of viral and ...
Kerstin Fischer, Stefan Finke, Anne Balkema-Buschmann, Axel Karger, Martin H. Groschup, Lucie Sauerhering, Sandra Diederich, Eileen Stroh, Andrea Maisner, Vinicius Pinho dos Reis   +9 more
openaire   +3 more sources

Characterisation of localised pigment accumulation in brains of eastern grey kangaroos (Macropus giganteus) after clinical disease due to chronic Phalaris species toxicosis

Australian Veterinary Journal, EarlyView.
A progressive tremorgenic syndrome characterised by ataxia and head nodding is well documented in sheep and cattle affected by chronic Phalaris toxicosis (CPT), and is increasingly documented in the eastern grey kangaroo {(EGK), Macropus giganteus} in southeastern Australia.
C El‐Hage, T Chen, L Tatarczuch, J Hufschmid, LF Skerratt, P Whiteley, N Davis, R Ploeg   +7 more
wiley   +1 more source

Dendritic cells in plasmodium infection [PDF]

, 2008
Infection with Plasmodium parasites (malaria) contributes greatly to morbidity and mortality in affected areas. Interaction of the protozoan with the immune system has a critical role in the pathogenesis of the disease, but may also hold a key to ...
Alonso, Bejon, Britta C Urban, Bruna-Romero, deWalick, Greenwood, Park, Patel, Perry, Pichyangkul, Pouniotis, Skorokhod, Stephen M Todryk, Todryk, Wong, Wykes   +15 more
core   +2 more sources

Prevalence of vector‐borne pathogens Ehrlichia canis, Babesia spp. and Dirofilaria immitis in dogs in Townsville, far north Queensland

Australian Veterinary Journal, EarlyView.
Ehrlichia canis, Babesia spp. and Dirofilaria immitis are blood‐borne pathogens transmitted to dogs by arthropods. The aim of the current study was to investigate the prevalence of E. canis, Babesia spp. and D. immitis in domestic dogs, aged 6 months or older, in Townsville, in far north Queensland, Australia.
K Gerber, JA Picard, J Elliman, CJ Joone, Y Indrawirawan, CC Constantinoiu   +5 more
wiley   +1 more source