Results 251 to 260 of about 44,629 (299)

Possible functions of tumor-associated carbohydrate antigens

Current Opinion in Immunology, 1991
Expression of some tumor-associated carbohydrate antigens may define the stage, rate and phenotype of tumor progression and may have prognostic value. Some of these antigens are now recognized as adhesion molecules that define the site of metastasis. Monoclonal antibodies to tumor-associated carbohydrate antigens, or the antigens themselves, may serve ...
exaly   +3 more sources

Tumor-Associated Carbohydrate Antigens Targeting Immunotherapy

Trends in Glycoscience and Glycotechnology, 2021
YASUYUKI MATSUMOTO
exaly   +2 more sources

Enzymatic Synthesis of Tumor-Associated Carbohydrate Antigen Globo-H Hexasaccharide

Organic Letters, 2008
We report the enzymatic synthesis of an important tumor-associated carbohydrate antigen, Globo-H hexasaccharide. Starting with Lac-OBn as the initial acceptor, this approach employs three glycosyltransferases: LgtC, an alpha1,4-galactosyltransferase; LgtD, a bifunctional beta1,3-galactosyl/beta1,3-N-acetylgalactosaminyltransferase; and WbsJ, an alpha1 ...
Doris M, Su   +5 more
openaire   +3 more sources

Biosignals Modulated by Tumor‐Associated Carbohydrate Antigens

Annals of the New York Academy of Sciences, 2006
Abstract:  Based on the remodeling of glycosphingolipids on the human tumor cell lines with manipulation of glycosyltransferase genes, roles of sugar moieties in tumor‐associated carbohydrate antigens have been analyzed. Two main topics, that is, the roles of ganglioside GD3 in human malignant melanomas and those of GD2 in small cell lung cancer (SCLC)
Koichi, Furukawa   +3 more
openaire   +2 more sources

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