Results 11 to 20 of about 2,011,135 (332)
Immunoelectron Microscopy of Viral Antigens [PDF]
Current Protocols in Microbiology, 2019 Immunoelectron microscopy is a powerful technique for identifying viral antigens and determining their structural localization and organization within vaccines and viruses.
Neetu M. Gulati +3 more
semanticscholar +4 more sources
Recombinant Antigens in Viral Diagnosis [PDF]
Transfusion Medicine and Hemotherapy, 1992 DNA-fragments coding for a variety of different viral antigens have been cloned and expressed in E. coli. Selected purified recombinant antigens were used for detection of specific antibodies by the means of ELISA technique. This approach has been used for the development of four different ELISAs for the detection of HIV- and EBV-specific antibodies.
Vornhagen, R. +7 more
openaire +5 more sources
Antigen Processing of a Short Viral Antigen by Proteasomes [PDF]
Journal of Biological Chemistry, 2006 Mass spectrometry (MS)-based methods coupled to reverse phase chromatography separation are a useful technology to analyze complex peptide pools that are comprised of different peptides with unrelated sequences. In antigen presentation, proteasomes generate a set of short peptides that are closely related and overlapping and in some instances may even ...
Lopez, Daniel +4 more
openaire +4 more sources
HNSCC: Tumour Antigens and Their Targeting by Immunotherapy
Cells, 2020 Head and neck squamous cell carcinomas (HNSCC) are a heterogeneous group of malignant tumours typically caused by alcohol and tobacco consumption, although an increasing number of HNSCC arise due to persistent infection with high-risk human papilloma ...
Adrian von Witzleben +4 more
doaj +1 more source
Oncogenic viral antigens for engineered T cell immunotherapy: Challenges and opportunities
Medicine Advances, 2023 Viruses that cause malignancies such as hepatocellular carcinoma and cervical cancer are the cause of approximately 20% of all human cancers. In recent years, engineered T cell immunotherapy targeting tumor‐associated antigens (TAAs) has had some success
Haipeng Zhang +5 more
doaj +1 more source
Biomedicines, 2023 The gastrointestinal tract can be heavily infected by SARS-CoV-2. Being an auto-immunogenic virus, SARS-CoV-2 represents an environmental factor that might play a role in gut-associated autoimmune diseases.
Aaron Lerner +2 more
doaj +1 more source
Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics
Cell Reports, 2021 Summary: The human leukocyte antigen (HLA)-bound viral antigens serve as an immunological signature that can be selectively recognized by T cells. As viruses evolve by acquiring mutations, it is essential to identify a range of presented viral antigens ...
Adi Nagler +18 more
doaj +1 more source
bioRxiv, 2020 The adaptive immune system is highly sensitive to arrayed antigens, and multivalent display of viral glycoproteins on symmetric scaffolds has been found to substantially increase the elicitation of antigen-specific antibodies.
G. Ueda +24 more
semanticscholar +1 more source
Antigen identification and high-throughput interaction mapping by reprogramming viral entry
Nature Methods, 2021 Deciphering immune recognition is critical for understanding a broad range of diseases and for the development of effective vaccines and immunotherapies.
C. Dobson +11 more
semanticscholar +1 more source
Radioimmunoassays of hidden viral antigens. [PDF]
Proceedings of the National Academy of Sciences, 1982 Antigens corresponding to infectious agents may be present in biological specimens only in a cryptic form bound to antibodies and, thus, may elude detection. We describe a solid phase technique for separation of antigens from antibodies. Immune complexes are precipitated from serum by polyethylene glycol, dissociated with NaSCN, and adsorbed onto ...
Krugman S +3 more
openaire +4 more sources