Results 11 to 20 of about 243,841 (269)
Biomedicines, 2023 The gastrointestinal tract can be heavily infected by SARS-CoV-2. Being an auto-immunogenic virus, SARS-CoV-2 represents an environmental factor that might play a role in gut-associated autoimmune diseases.
Aaron Lerner +2 more
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Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics
Cell Reports, 2021 Summary: The human leukocyte antigen (HLA)-bound viral antigens serve as an immunological signature that can be selectively recognized by T cells. As viruses evolve by acquiring mutations, it is essential to identify a range of presented viral antigens ...
Adi Nagler +18 more
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Radioimmunoassays of hidden viral antigens. [PDF]
Proceedings of the National Academy of Sciences, 1982 Antigens corresponding to infectious agents may be present in biological specimens only in a cryptic form bound to antibodies and, thus, may elude detection. We describe a solid phase technique for separation of antigens from antibodies. Immune complexes are precipitated from serum by polyethylene glycol, dissociated with NaSCN, and adsorbed onto ...
Krugman S +3 more
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, 2016 Laboratorians continually seek methodologies that yield accurate results in a timely fashion, are cost effective, and require less technical expertise. Diagnosis of viral infections via viral antigen detection methods such as immunofluorescence (FA), immunochromatography (lateral flow) (IC), and enzyme immunoassays (EIA) offer many of these attractive ...
Ryan F. Relich, Diane S. Leland
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How Does HTLV-1 Undergo Oncogene-Dependent Replication Despite a Strong Immune Response?
Frontiers in Microbiology, 2018 In 1987, Mitsuaki Yoshida proposed the following model (Yoshida and Seiki, 1987): “... T-cells activated through the endogenous p40x would express viral antigens including the envelope glycoproteins which are exposed on the cell surface.
Hélène Gazon +13 more
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Frontiers in Immunology, 2019 Cytotoxic CD8+ T cell (CTL) responses play an essential role in antiviral immunity. Here, we focused on the activation of CTL which recognize epitopes derived from viral or recombinant antigens with either early or late expression kinetics after ...
Sha Tao +5 more
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Vaccines, 2019 Background: Flexuous rod-shape nanoparticles—made of the coat protein of papaya mosaic virus (PapMV)—provide a promising vaccine platform for the presentation of viral antigens to immune cells.
Marie-Ève Laliberté-Gagné +7 more
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Treating cancer as an infectious disease--viral antigens as novel targets for treatment and potential prevention of tumors of viral etiology. [PDF]
PLoS ONE, 2007 Nearly 20% of human cancers worldwide have an infectious etiology with the most prominent examples being hepatitis B and C virus-associated hepatocellular carcinoma and human papilloma virus-associated cervical cancer. There is an urgent need to find new
Xing Guo Wang +6 more
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Инфекция и иммунитет, 2021 Age-related macular degeneration (AMD) and central serous chorioretinopathy (CSC) are diseases targeting the posterior segment of the eye that often lead to lowered visual functions. Pathogenesis of such disorders largely remains unclear.
V. V. Neroev +7 more
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Pathogens, 2020 The ongoing SARS-CoV-2 pandemic has triggered multiple efforts for serological tests and vaccine development. Most of these tests and vaccines are based on the Spike glycoprotein (S) or the Nucleocapsid (N) viral protein.
Eric Dumonteil, Claudia Herrera
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