Results 21 to 30 of about 270,928 (312)

Immunodominance of lytic cycle antigens in Epstein-Barr virus-specific CD4+ T cell preparations for therapy. [PDF]

open access: yes, 2007
Epstein-Barr virus (EBV) is associated with a number of human malignancies. EBV-positive post-transplant lymphoproliferative disease in solid organ and hematopoietic stem cell transplant recipients has been successfully treated by the adoptive transfer ...
Burdach, S.   +36 more
core   +1 more source

Alpha/beta and gamma interferons are induced by infection with noncytopathic bovine viral diarrhea virus in vivo [PDF]

open access: yes, 2002
In contrast to the results of previous in vitro studies, experimental infection of calves with noncytopathic bovine viral diarrhea virus (ncpBVDV) was found to induce strong alpha/beta and gamma interferon responses in gnotobiotic animals.
Carr, B V   +6 more
core   +1 more source

Treating cancer as an infectious disease--viral antigens as novel targets for treatment and potential prevention of tumors of viral etiology. [PDF]

open access: yesPLoS ONE, 2007
Nearly 20% of human cancers worldwide have an infectious etiology with the most prominent examples being hepatitis B and C virus-associated hepatocellular carcinoma and human papilloma virus-associated cervical cancer. There is an urgent need to find new
Xing Guo Wang   +6 more
doaj   +1 more source

Features of IgG-antibodies production to individual Cytomegalovirus proteins in various eye diseases (age-related macular degeneration and central serous chorioretinopathy)

open access: yesИнфекция и иммунитет, 2021
Age-related macular degeneration (AMD) and central serous chorioretinopathy (CSC) are diseases targeting the posterior segment of the eye that often lead to lowered visual functions. Pathogenesis of such disorders largely remains unclear.
V. V. Neroev   +7 more
doaj   +1 more source

Polymorphism and Selection Pressure of SARS-CoV-2 Vaccine and Diagnostic Antigens: Implications for Immune Evasion and Serologic Diagnostic Performance

open access: yesPathogens, 2020
The ongoing SARS-CoV-2 pandemic has triggered multiple efforts for serological tests and vaccine development. Most of these tests and vaccines are based on the Spike glycoprotein (S) or the Nucleocapsid (N) viral protein.
Eric Dumonteil, Claudia Herrera
doaj   +1 more source

PRELIMINARY STUDIES ON THE APPLICATION OF SOME RECENT TECHNIQUES IN THE DETECTION OF RINDERPEST VIRAL ANTIGENS AND ANTIBODIES [PDF]

open access: yesAssiut Veterinary Medical Journal, 1987
In this work, some of the recently applied serological techniques, have been developed and evaluated for he detection of rinderpest viral antigens and antibodies.
H.M. MADBOLY   +5 more
doaj   +1 more source

Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection

open access: yes, 2002
Deletion, anergy, and a spectrum of functional impairments can affect virus-specific CD8 cells in chronic viral infections. Here we characterize a low frequency population of CD8 cells present in chronic hepatitis B virus (HBV) infection which survive in
Ogg, GS   +29 more
core   +1 more source

Vaccinia virus expressing ICP47 : a novel platform for cancer vaccines highlighting tumor epitopes and hiding viral antigens [PDF]

open access: yes, 2010
Background Recombinant poxviruses expressing tumor associated antigens (TAAs) are evaluated since 20 years as immunogenic vaccine vector in clinical trials.
Raafat, Nermin Abdel Fattah
core   +1 more source

ASSESSMENT OF THE ACTUAL AND POTENTIAL EPIDEMIOLOGYCAL SITUATION OF THE VIRAL HEPATITIS C AND B BASED BY LABORATORY DATA IN THE “DOCTOR PARAMONOV’S CLINIC” IN SARATOV CITY AND SARATOV REGION

open access: yesПаёми Сино, 2017
Objective: Study of the prevalence of the viral hepatitis C and viral hepatitis B in the territory of Saratov City and Saratov Region, analysis of the revealed cases and discussion of laboratory diagnostics issues.
V.V. NIKITINA   +3 more
doaj   +1 more source

HLA and immunodominance in viral infection: T-cell responses in protection and immunopathogenesis [PDF]

open access: yesMicrobiology Australia, 2021
The protective role of T cells in viral infection is well described. T cells generally mediate anti-viral immune responses via direct cytotoxicity and production of pro-inflammatory cytokines, by providing help to B cells and by promotion of memory ...
Suzi McCarthy, Allison Imrie
doaj  

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