Results 11 to 20 of about 270,928 (312)

SARS-CoV-2 Gut-Targeted Epitopes: Sequence Similarity and Cross-Reactivity Join Together for Molecular Mimicry

open access: yesBiomedicines, 2023
The gastrointestinal tract can be heavily infected by SARS-CoV-2. Being an auto-immunogenic virus, SARS-CoV-2 represents an environmental factor that might play a role in gut-associated autoimmune diseases.
Aaron Lerner   +2 more
doaj   +1 more source

Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics

open access: yesCell Reports, 2021
Summary: The human leukocyte antigen (HLA)-bound viral antigens serve as an immunological signature that can be selectively recognized by T cells. As viruses evolve by acquiring mutations, it is essential to identify a range of presented viral antigens ...
Adi Nagler   +18 more
doaj   +1 more source

Immunoelectron Microscopy of Viral Antigens [PDF]

open access: yesCurrent Protocols in Microbiology, 2019
AbstractImmunoelectron microscopy is a powerful technique for identifying viral antigens and determining their structural localization and organization within vaccines and viruses. While traditional negative staining transmission electron microscopy provides structural information, identity of components within a sample may be confounding ...
Gulati, Neetu M.   +3 more
openaire   +2 more sources

Presentation of CMV immediate-early antigen to cytolytic T lymphocytes is selectively prevented by viral genes expressed in the early phase [PDF]

open access: yes, 1989
The regulation of antigen processing and presentation to MHC class I-restricted cytolytic T lymphocytes was studied in cells infected with murine cytomegalovirus. Recognition by cytolytic T lymphocytes of the phosphoprotein pp89, the immunodominant viral
Reddehase, Matthias J.   +7 more
core   +1 more source

How Does HTLV-1 Undergo Oncogene-Dependent Replication Despite a Strong Immune Response?

open access: yesFrontiers in Microbiology, 2018
In 1987, Mitsuaki Yoshida proposed the following model (Yoshida and Seiki, 1987): “... T-cells activated through the endogenous p40x would express viral antigens including the envelope glycoproteins which are exposed on the cell surface.
Hélène Gazon   +13 more
doaj   +1 more source

Recognition of viral glycoproteins by influenza A-specific cross- reactive cytolytic T lymphocytes [PDF]

open access: yes, 1980
Two populations of cytolytic T lymphocytes (CTL) generated after influenza A virus infection can be distinguished into one with specificity for the sensitizing hemagglutinin type and a second with cross-reactivity for antigens induced by other type-A ...
Klenk, H   +17 more
core   +1 more source

Sequestration of Late Antigens Within Viral Factories Impairs MVA Vector-Induced Protective Memory CTL Responses

open access: yesFrontiers in Immunology, 2019
Cytotoxic CD8+ T cell (CTL) responses play an essential role in antiviral immunity. Here, we focused on the activation of CTL which recognize epitopes derived from viral or recombinant antigens with either early or late expression kinetics after ...
Sha Tao   +5 more
doaj   +1 more source

Histocompatibility antigens in viral warts

open access: yesActa Dermato-Venereologica, 1982
One hundred patients with viral warts and 108 apparently healthy matched controls were typed for HLA-A and B antigens. No significant difference in the frequencies of antigens was revealed, which suggested that a possible genetic trend in warts is at least not related to A and B loci of the histocompatibility system.
R, Friedman-Birnbaum   +4 more
openaire   +2 more sources

Increased Immunogenicity of Full-Length Protein Antigens through Sortase-Mediated Coupling on the PapMV Vaccine Platform

open access: yesVaccines, 2019
Background: Flexuous rod-shape nanoparticles—made of the coat protein of papaya mosaic virus (PapMV)—provide a promising vaccine platform for the presentation of viral antigens to immune cells.
Marie-Ève Laliberté-Gagné   +7 more
doaj   +1 more source

Immunity to Intracellular Salmonella Depends on Surface-associated Antigens [PDF]

open access: yes, 2012
Invasive Salmonella infection is an important health problem that is worsening because of rising antimicrobial resistance and changing Salmonella serovar spectrum.
Rizos Konstantin   +50 more
core   +1 more source

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