Generation of virus-specific cytotoxic T cells in vitro II. Induction requirements with functionally inactivated virus preparations [PDF]
, 1980 Using noninfectious Sendai virus preparations after selective enzymatic digestion of either of the two viral envelope glycoproteins, it was possible to study the effect of different virion-cell membrane interactions on virus-specific cytotoxic T ...
Bosslet +27 more
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Role of early viral surface antigens in cellular immune response to vaccinia virus [PDF]
, 1976 Infection of mice with the vaccinia virus strain WR, Elstree or DIs, a conditional lethal mutant of vaccinia virus, resulted in the generation of vaccinia virus-specific sensitized cytolytic T lymphocytes (CTL).
Ertl, H., Koszinowski, Ulrich H.
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Modulation of antigen-specific T-cells as immune therapy for chronic infectious diseases and cancer [PDF]
, 2014 Copyright: © 2014 Li, Symonds, Miao, Sanderson and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Abraham +55 more
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The outbreak of SARS-CoV-2 pneumonia calls for viral vaccines
npj Vaccines, 2020 The outbreak of 2019-novel coronavirus disease (COVID-19) that is caused by SARS-CoV-2 has spread rapidly in China, and has developed to be a Public Health Emergency of International Concern.
Weilong Shang +3 more
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, 2016 Laboratorians continually seek methodologies that yield accurate results in a timely fashion, are cost effective, and require less technical expertise. Diagnosis of viral infections via viral antigen detection methods such as immunofluorescence (FA), immunochromatography (lateral flow) (IC), and enzyme immunoassays (EIA) offer many of these attractive ...
Ryan F. Relich, Diane S. Leland
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How Does HTLV-1 Undergo Oncogene-Dependent Replication Despite a Strong Immune Response?
Frontiers in Microbiology, 2018 In 1987, Mitsuaki Yoshida proposed the following model (Yoshida and Seiki, 1987): “... T-cells activated through the endogenous p40x would express viral antigens including the envelope glycoproteins which are exposed on the cell surface.
Hélène Gazon +13 more
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Integration of a virus membrane protein into the lipid bilayer of target cells as a prerequisite for immune cytolysis [PDF]
, 1979 Structural requirements for membrane antigens on target cells to mediate immune cytolysis were studied in a model system with purified membrane proteins from Semliki Forest virus (SFV). These SFV spike proteins were isolated in the form of detergent- and
Barz, D. +3 more
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Human natural killer cells mediate adaptive immunity to viral antigens
Science immunology, 2019 Vaccination or childhood infection elicits antigen-specific, long-lived immunological memory in human natural killer cells. Recall responses by human NK cells One of the traditional dividing lines separating innate and adaptive immunity was the ...
Rana Nikzad +13 more
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Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection [PDF]
, 1984 Interstitial pneumonia linked with reactivation of latent human cytomegalovirus due to iatrogenic immunosuppression can be a serious complication of bone marrow transplantation therapy of aplastic anaemia and acute leukaemia1.
A Ebeling +36 more
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WDFY4 is required for cross-presentation in response to viral and tumor antigens
Science, 2018 Adding to the cross-presentation family Immune responses to viral or tumor antigens are typically initiated by the process of cross-presentation. Cross-presentation is believed to be the major way that innate immune cells, such as the classical dendritic
Derek J. Theisen +19 more
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