Results 21 to 30 of about 387,314 (311)
Frontiers in Immunology, 2019 Cytotoxic CD8+ T cell (CTL) responses play an essential role in antiviral immunity. Here, we focused on the activation of CTL which recognize epitopes derived from viral or recombinant antigens with either early or late expression kinetics after ...
Sha Tao +5 more
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Vaccines, 2019 Background: Flexuous rod-shape nanoparticles—made of the coat protein of papaya mosaic virus (PapMV)—provide a promising vaccine platform for the presentation of viral antigens to immune cells.
Marie-Ève Laliberté-Gagné +7 more
doaj +1 more source
Histocompatibility antigens in viral warts
Acta Dermato-Venereologica, 1982 One hundred patients with viral warts and 108 apparently healthy matched controls were typed for HLA-A and B antigens. No significant difference in the frequencies of antigens was revealed, which suggested that a possible genetic trend in warts is at least not related to A and B loci of the histocompatibility system.
R, Friedman-Birnbaum +4 more
openaire +2 more sources
Integration of a virus membrane protein into the lipid bilayer of target cells as a prerequisite for immune cytolysis [PDF]
, 1979 Structural requirements for membrane antigens on target cells to mediate immune cytolysis were studied in a model system with purified membrane proteins from Semliki Forest virus (SFV). These SFV spike proteins were isolated in the form of detergent- and
Barz, D. +3 more
core +1 more source
Non-viral chimeric antigen receptor (CAR) T cells going viral
Immuno-Oncology and Technology, 2023 Chimeric antigen receptor (CAR) T cell therapy has made significant strides in the treatment of B-cell malignancies, but its application in treating solid tumors still poses significant challenges. Particularly, the widespread use of viral vectors to deliver CAR transgenes into T cells comes with limitations, including high costs and regulatory ...
H. Balke-Want +8 more
openaire +3 more sources
Vesicular stomatitis virus glycoprotein is necessary for H-2-restricted lysis of infected cells by cytotoxic T lymphocytes [PDF]
, 1978 Vesicular stomatitis virus (VSV) elicited cytotoxic thymus-derived lymphocytes (CTLs) in mice of the BALB/c and three congenic strains (BALB.b, BALB.k, BALB.HTG).
Baltimore, David +3 more
core +2 more sources
Treating cancer as an infectious disease--viral antigens as novel targets for treatment and potential prevention of tumors of viral etiology. [PDF]
PLoS ONE, 2007 Nearly 20% of human cancers worldwide have an infectious etiology with the most prominent examples being hepatitis B and C virus-associated hepatocellular carcinoma and human papilloma virus-associated cervical cancer. There is an urgent need to find new
Xing Guo Wang +6 more
doaj +1 more source
Инфекция и иммунитет, 2021 Age-related macular degeneration (AMD) and central serous chorioretinopathy (CSC) are diseases targeting the posterior segment of the eye that often lead to lowered visual functions. Pathogenesis of such disorders largely remains unclear.
V. V. Neroev +7 more
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Behaviour of non-donor specific antibodies during rapid re-synthesis of donor specific HLA antibodies after antibody incompatible renal transplantation [PDF]
, 2013 Background: HLA directed antibodies play an important role in acute and chronic allograft rejection. During viral infection of a patient with HLA antibodies, the HLA antibody levels may rise even though there is no new immunization with antigen ...
Briggs, David, Dr. +11 more
core +2 more sources
Pathogens, 2020 The ongoing SARS-CoV-2 pandemic has triggered multiple efforts for serological tests and vaccine development. Most of these tests and vaccines are based on the Spike glycoprotein (S) or the Nucleocapsid (N) viral protein.
Eric Dumonteil, Claudia Herrera
doaj +1 more source