Results 41 to 50 of about 387,314 (311)
Absence of CTL Responses to Early Viral Antigens Facilitates Viral Persistence [PDF]
The Journal of Immunology, 2008 Abstract CD8+ T cells are crucial for the control of intracellular pathogens such as viruses and some bacteria. Using lymphocytic choriomeningitis virus (LCMV) infection of mice—the prototypic arenavirus evolutionarily closely related to human Lassa fever and South American hemorrhagic fever viruses, we have shown previously that the ...
Schildknecht, A +4 more
openaire +3 more sources
Infectious diseases and autoimmunity [PDF]
, 2011 Introduction: Autoimmunity occurs when the immune system recognizes and attacks host tissue. In addition to genetic factors, environmental triggers (in particular viruses, bacteria and other infectious pathogens) are thought to play a major role in the ...
Deidda, Silvia +3 more
core +1 more source
Frontiers in Cellular and Infection MicrobiologyBackgroundViral vaccines have been proven significant in protecting us against viral diseases such as COVID-19. To better understand and design viral vaccines, it is critical to systematically collect, annotate, and analyse various viral vaccines and ...
Anthony Huffman +8 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2017 T cell immunity is critical in controlling human cytomegalovirus (HCMV) infection in transplant recipients, and T cells targeting viral immediate early proteins such as IE1, IE2 and pp65 have been speculated to be more effective against reactivation ...
Aimin Tang +8 more
doaj +1 more source
HIV & AIDS Review. International Journal of HIV-Related Problems, 2019 Human immunodeficiency virus (HIV) infection during pregnancy is still a major problem worldwide, especially in developing countries. Although administration of anti-retroviral drugs has succeeded in reducing mother-to-child transmission, poor obstetric ...
Artana Putra IW, Ketut Suwiyoga
doaj +1 more source
A Genetic Locus Regulates the Expression of Tissue-Specific mRNAs from Multiple Transcription Units [PDF]
, 1982 129 GIX- mice, unlike animals of the congeneic partner strain GIX+, do not express significant amounts of the retroviral antigens gp70 and p30. Evidence is presented indicating that the GIX phenotype is specified by a distinct regulatory gene acting on ...
Lerner, Richard A. +2 more
core +2 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Virology Journal, 2007 Background The binding of viral-specific antibodies to cell-surface antigens usually results in down modulation of the antigen through redistribution of antigens into patches that subsequently may be internalized by endocytosis or may form caps that can ...
Gómez-Garcia Beatriz +3 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Behind the central nervous system, neurotropic viruses can reach and persist even in the enteric nervous system (ENS), the neuronal network embedded in the gut wall.
Paola Brun +11 more
doaj +1 more source
Viral proteins expressed in the protozoan parasite Eimeria tenella are detected by the chicken immune system [PDF]
, 2016 BACKGROUND: Eimeria species are parasitic protozoa that cause coccidiosis, an intestinal disease commonly characterised by malabsorption, diarrhoea and haemorrhage that is particularly important in chickens.
Blake, D P +6 more
core +3 more sources