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The antigenicity of carcinoembryonic antigen in man
International Journal of Cancer, 1975AbstractBinding of globulins to 125I CEA was detected in 10 of 24 sera from patients with cancer, 13 of 26 sera from blood donors, and 7 of 27 supernates of tumor‐cell suspensions. Binding was predominantly by IgM in 10 of 14 sera tested by radioimmunoelectrophoresis.
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Antigen presentation, antigen-presenting cells and antigen processing
Current Opinion in Immunology, 1988To summarize, during the period under review there have been considerable advances in our understanding of how antigen is associated with MHC on the surface of a presenting cell. Basic rules which govern this association have been confirmed as including both the nature and the configuration of the antigen.
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ON THE ANTIGENICITY OF INSULIN
Canadian Journal of Biochemistry and Physiology, 1957On the basis of body weight, mice showed a higher percentage survival to large doses of insulin than did rabbits and these in turn were more resistant to insulin than guinea pigs. Antibodies to insulin were induced in five species of animals. Anti-insulins produced by the guinea pig, rabbit, sheep, and horse can each neutralize insulin extracted from ...
P. J. Moloney, L. Goldsmith
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How antigenic are antigenic peptides?
Biopolymers, 1983AbstractMost of a protein surface is potentially antigenic, consisting of numerous overlapping domains each complementary to antibody‐combining sites. These domains may include peptide sequences that are demonstrably antigenic but only when antibodies from the appropriate host individuals and species are used.
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Antigens, Antigenicity, and Immunogenicity
2015The initiation of an immune response requires the interaction between T cells, B cells, and antigen-presenting cells (APCs), which form central components of almost all immune responses, and antigens, substances recognized as foreign by the immune system. The ability of an antigen to combine with antibody reflects the property of antigenicity.
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Antigen-antigen receptor interactions
Current Opinion in Structural Biology, 1991Abstract The genetic basis of antigen receptor diversity is understood for both B and T cell systems. Structural aspects of five specific antibody-antigen interactions have also been described. During the past year, new data comparing the structures of liganded and unliganded antibodies have given support to the hypothesis that there exists a ...
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Identification of tumor antigens with immunopeptidomics
Nature Biotechnology, 2021Chloé Chong +2 more
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Antigenic Determinants of Carcinoembryonic Antigen
Scandinavian Journal of Immunology, 1978Radioimmunoassays for carcinoembryonic antigen (CEA) have been established using a variety of different antisera raised in goat, monkey, rabbit, guinea pig and rat. The extent to which different antigens compete for antibodies in the sera has been estimated.
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TWO ANTIGENIC SPECIFICITIES IN THE AUSTRALIA ANTIGEN
Australian Journal of Experimental Biology and Medical Science, 1971SummaryTwo antigenic specificities have been detected in Australia antigens identified in Melbourne. One specificity was common to all antigens studied, the other was observed in approximately 50% of patients with Au‐positive acute viral hepatitis and also in all of a group of antigen‐positive institutionalized Mongols.In patients with acute viral ...
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Immunochemical quantitation of antigens by single radial immunodiffusion.
Immunochemistry, 1965G. Mancini, A. Carbonara, J. Heremans
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