Results 21 to 30 of about 884,279 (321)

Analysis of EVs from patients with advanced pancreatic cancer identifies antigens and miRNAs with predictive value

Molecular Therapy: Methods & Clinical Development, 2023
The identification of predictive factors for treatment of pancreatic cancer (PC) is an unmet clinical need. In the present work, we analyzed blood-derived extracellular vesicles (EVs) from patients with advanced PC in order to find a molecular signature ...
Ivan Vannini, Tania Rossi, Mattia Melloni, Martina Valgiusti, Milena Urbini, Alessandro Passardi, Giulia Bartolini, Chiara Gallio, Irene Azzali, Sara Bandini, Valentina Ancarani, Lorenzo Montanaro, Giovanni Luca Frassineti, Francesco Fabbri, Ilario Giovanni Rapposelli   +14 more
doaj  

The effects of symmetry on the dynamics of antigenic variation [PDF]

J. Math. Biol. 66, 115-137 (2013), 2012
In the studies of dynamics of pathogens and their interactions with a host immune system, an important role is played by the structure of antigenic variants associated with a pathogen. Using the example of a model of antigenic variation in malaria, we show how many of the observed dynamical regimes can be explained in terms of the symmetry of ...
arxiv   +1 more source

Designing and Construction of a Cloning Vector Encoding mtb32C and mpt51 Fragments of Mycobacterium Tuberculosis as a DNA Vaccine Candidate [PDF]

Iranian Journal of Pathology, 2018
Background & objective:  Tuberculosis (TB) remains a major cause of death around the world. Bacillus Calmette Guérin (BCG) is the only vaccine used in TB prevention that has a protective effect in children, but its effectiveness declines in adults ...
Faria Hasanzadeh Haghighi, Ehsan Aryan, Mohammad Derakhshan, Aida Gholoobi, Zahra Meshkat   +4 more
doaj  

Humoral immune responses in mice immunized with region of difference DNA vaccine constructs of pUMVC6 and pUMVC7

International Journal of Mycobacteriology, 2017
Background: We aimed to study the antigen-specific antibody responses in mice immunized with recombinant DNA vaccines constructs of pUMVC6 and pUMVC7, containing RD1 and RD9 genes of Mycobacterium tuberculosis.
Shumaila N. M. Hanif, A S Mustafa
doaj   +1 more source

Enterocytes in Food Hypersensitivity Reactions

Animals, 2021
Food hypersensitivity reactions are adverse reactions to harmless dietary substances, whose causes are hidden within derangements of the complex immune machinery of humans and mammals.
Maja Krstić Ristivojević, Danijela Apostolović, Katarina Smiljanić   +2 more
doaj   +1 more source

Aspectos estruturais da membrana eritrocitária Structural aspects of the erythrocyte membrane

Revista Brasileira de Hematologia e Hemoterapia, 2007
Este artigo descreve as estruturas e funções da membrana eritrocitária e sua importância na medicina transfusional. A membrana eritrocitária é uma das membranas mais conhecidas em termos de estrutura, função e genética. Como qualquer membrana plasmática,
Priscila Murador, Elenice Deffune
doaj   +1 more source

Verificación del desempeño de la prueba rápida "AMP Rapid Test SARS-CoV-2 IgG/IgM- Cassettes"

Infectio, 2021
Objective: We aimed to realize a verification of the performance of the rapid serological tests used in Risaralda department.Methods: Analytical, cross-sectional study.
Diana María Gil-Villa
doaj   +1 more source

Structure-Guided Redesign Improves NFL HIV Env Trimer Integrity and Identifies an Inter-Protomer Disulfide Permitting Post-Expression Cleavage

Frontiers in Immunology, 2018
Soluble HIV-1 envelope glycoprotein (Env) trimers are under active investigation as vaccine candidates in relevant pre-clinical models. Like SOSIPs, the cleavage-independent native flexibly linked (NFL) trimers are faithful mimics of the Env spike. Here,
Lifei Yang, Shailendra Kumar Sharma, Christopher Cottrell, Javier Guenaga, Karen Tran, Richard Wilson, Anna-Janina Behrens, Max Crispin, Max Crispin, Max Crispin, Natalia de Val, Richard T. Wyatt, Richard T. Wyatt, Richard T. Wyatt   +13 more
doaj   +1 more source

Acellular Pertussis Vaccines Induce Anti-pertactin Bactericidal Antibodies Which Drives the Emergence of Pertactin-Negative Strains

Frontiers in Microbiology, 2020
Despite high vaccination coverage, Bordetella pertussis the causative agent of whooping cough is still a health concern worldwide. A resurgence of pertussis cases has been reported, particularly in countries using acellular vaccines with waning immunity ...
Elodie Lesne, Breeze E. Cavell, Irene Freire-Martin, Ruby Persaud, Frances Alexander, Stephen Taylor, Mary Matheson, Cécile A. C. M. van Els, Andrew Gorringe   +8 more
doaj   +1 more source

CD Antigens 2001 [PDF]

Modern Pathology, 2001
Abstract: The most recent Human Leucocyte Differentiation Antigen Workshop (“HLDA7”) took place in 2000 in Harrogate, UK and the proceedings are about to be published (Leucocyte Typing VII). New Sections were introduced in this Workship (Dendritic cells, Stem/progenitor cells, Erythroid cells and Carbohydrate Structures) and monoclonal antibodies were ...
Mason, D., Andre, P., Bensussan, A., Buckley, C., Civin, C., Clark, E., de Haas, M., Goyert, S., Hadam, M., Hart, D., Horejsi, V., Meuer, S., Morrissey, J., Schwartz-Albiez, R., Shaw, S., Simmons, D., Uguccioni, M., van der Schoot, E., Vivier, E., Zola, H.   +19 more
openaire   +18 more sources