Results 131 to 140 of about 6,856 (183)

Oral 18-methoxycoronaridine activity in simian and murine <i>Leishmania amazonensis</i> infection. [PDF]

Front Pharmacol
Delorenzi JC, Melo TS, Silveira FT, Carneiro LA, Campos MB, Cunha MR, Ricci EL, Fukushima AR, Hurst SL, Freeman SM, Almeida-Saavedra MS, Mourad AM, Sacchelli-Ramos C, Delorenzi LBO, Delorenzi GB, Saraiva EM.   +15 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Antileishmanial agents part-IV: synthesis and antileishmanial activity of novel terpenyl pyrimidines

European Journal of Medicinal Chemistry, 2005
Some novel N- and O-substituted terpenyl pyrimidines 4 (a-j) have been synthesized and screened for in vitro antileishmanial activity profile in promastigote model. Some of the compounds exhibited 100% inhibition at 10 microg ml(-1) concentration.
S N Suryawanshi, S N Suryawanshi
exaly   +3 more sources

Antileishmanial polyphenols from Garcinia vieillardii

Fìtoterapìâ, 2008
Seven xanthones, the new vieillardiixanthones B and C (1) and (7), pancixanthones A (2), B (3), 1,6-dihydroxyxanthone (6), pyranojacareubin and 5,6-O-dimethyl-2-deprenylrheediaxanthone together with two benzophenones, clusiachromene (4) and 3-geranyl-2,4,6-trihydroxybenzophenone (5) were isolated from the stem bark of the neocaledonian Garcinia ...
Patrice Le Pape, Anne Landreau, Pascal Richomme   +2 more
exaly   +4 more sources

Development of the Antileishmanial Vaccine

2021
Search for an efficacious antileishmanial vaccine has led to clinical trials of numerous vaccine candidates in the past few decades. As no promising candidate has emerged from these studies, novel vaccine modalities and vaccine assessment techniques are still emerging for antileishmanial vaccine development. Briefly, this chapter discusses: (a) history
Sunil, Kumar, Shubhranshu, Zutshi, Mukesh Kumar, Jha, Prashant, Chauhan, Bhaskar, Saha   +4 more
openaire   +2 more sources

The Antileishmanial Activity of Lepidines

The American Journal of Tropical Medicine and Hygiene, 1978
A series of lepidines (6-methoxy-4-methyl-8-aminoquinoline derivatives) was studied in a hamster-Leishmania donovani model. Members of this class were found to have activity many-fold that of the standard, meglumine antimoniate (Glucantime). One of them, 8-(6-diethylamino-hexylamino)-6-methoxy-4-methylquinoline, designated WR 6026, when given orally ...
K E, Kinnamon, E A, Steck, P S, Loizeaux, W L, Hanson, W L, Chapman, V B, Waits   +5 more
openaire   +2 more sources

Novel bisbenzimidazoles with antileishmanial effectiveness

Bioorganic & Medicinal Chemistry Letters, 2008
A small library of 2,2'-[(alpha,omega-alkanediylbis(oxyphenylene)]bis-1H-benzimidazoles has been prepared and screened in vitro against Pneumocystis carinii, Trypanosoma brucei rhodesiense, and Leishmania donovani. Among the six tested compounds two derivatives emerged as promising hits characterized by IC(50) values lower than that determined for ...
Mayence, A., Pietka, A., Collins, M.S., Cushion, M.T., Tekwani, B.L., Huang, T.L., Vanden Eynde, Jean-Jacques   +6 more
openaire   +3 more sources

In vitro Antileishmanial Activity of Inhibitors of Steroid Biosynthesis and Combinations of Antileishmanial Agents

The Journal of Parasitology, 1987
present in the hemolymph of replete females only at 10-8 M. Thus, hemolymph components at this concentration or below may be affected by specific antibodies directed against them. The main advantage of using ELISA for detection of host antibodies in the hemolymph of ticks was the small volume of hemolymph required (about 0.2 Al/tick).
J D, Berman, J V, Gallalee
openaire   +2 more sources

Antileishmanial activity of imidothiocarbamates and imidoselenocarbamates

Parasitology Research, 2010
In the present study, a family of 15 imidothio- and imidoselenocarbamates (1-15) analogs have been synthesized and screened for their in vitro antileishmanial potential against Leishmania infantum promastigotes. The six most active ones (2, 4, 7, 13, 14, and 15) were also tested in an axenic amastigote model.
David, Moreno, Daniel, Plano, Ylenia, Baquedano, Antonio, Jiménez-Ruiz, Juan Antonio, Palop, Carmen, Sanmartín   +5 more
openaire   +2 more sources

A new antileishmanial compound, phaseolinone

Biochemical and Biophysical Research Communications, 1990
Inclusion of phaseolinone, a newly described mycotoxin, at 20 micrograms per ml in a solid culture medium (blood agar overlay) and at 50 micrograms per ml in a liquid culture (medium 199) inhibited the growth of L. donovani promastigotes. About 90% of the motile promastigotes lost motility after exposure to 50 micrograms per ml of phaseolinone for 6-7 ...
R, Roy, G, Bhattacharya, K A, Siddiqui, R, Bhadra   +3 more
openaire   +2 more sources