Results 1 to 10 of about 92,685 (278)
Polymeric Nanocarriers for the Delivery of Antimalarials
Molecules, 2018 Malaria is an infectious disease caused by a protozoan parasite which is transmitted by female Anopheles mosquitoes around tropical and sub-tropical regions. Half of the world’s population is at risk of being infected by malaria.
Blessing A Aderibigbe
exaly +4 more sources
Frontiers in Pharmacology, 2021 Malaria is an endemic disease that affected 229 million people and caused 409 thousand deaths, in 2019. Disease control is based on early diagnosis and specific treatment with antimalarial drugs since no effective vaccines are commercially available to ...
Isabela P. Ceravolo +3 more
doaj +2 more sources
Marine Drugs, 2009 Malaria is an infectious disease causing at least 1 million deaths per year, and, unfortunately, the chemical entities available to treat malaria are still too limited.
Orazio Taglialatela-Scafati +1 more
doaj +4 more sources
Quinoline Antimalarials Increase the Antibacterial Activity of Ampicillin
Frontiers in Microbiology, 2021 Bacterial and malaria co-infections are common in malaria endemic countries and thus necessitate co-administration of antibiotics and antimalarials. There have long been anecdotal clinical reports of interactions between penicillins and antimalarial ...
Olajumoke A. Olateju +9 more
doaj +2 more sources
Exposing Anopheles mosquitoes to antimalarials blocks Plasmodium parasite transmission
Nature, 2019 Bites of Anopheles mosquitoes transmit Plasmodium falciparum parasites that cause malaria, which kills hundreds of thousands of people every year.
Douglas G Paton +2 more
exaly +2 more sources
High adherence to antimalarials and antibiotics under integrated community case management of illness in children less than five years in eastern Uganda. [PDF]
PLoS ONE, 2013 BackgroundDevelopment of resistance to first line antimalarials led to recommendation of artemisinin based combination therapies (ACTs). High adherence to ACTs provided by community health workers (CHWs) gave reassurance that community based ...
Joan N Kalyango +6 more
doaj +2 more sources
Tackling resistance: Emerging antimalarials and new parasite targets in the era of elimination [version 1; referees: 2 approved] [PDF]
F1000Research, 2018 Malaria remains a significant contributor to global human mortality, and roughly half the world’s population is at risk for infection with Plasmodium spp. parasites.
Matthews, Emily S, Odom John, Audrey R
core +3 more sources
Nature Communications, 2014 The quest for new antimalarial drugs, especially those with novel modes of action, is essential in the face of emerging drug-resistant parasites. Here we describe a new chemical class of molecules, pyrazoleamides, with potent activity against human ...
Akhil B Vaidya +2 more
exaly +2 more sources
Antimicrobial Agents and Chemotherapy, 2016 Fully synthetic endoperoxide antimalarials, namely, OZ277 (RBx11160; also known as arterolane) and OZ439 (artefenomel), have been approved for marketing or are currently in clinical development.
Tuo Yang, Stanley C Xie, Pengxing Cao
exaly +2 more sources
Lead Clinical and Preclinical Antimalarial Drugs Can Significantly Reduce Sporozoite Transmission to Vertebrate Populations [PDF]
, 2014 To achieve malarial elimination we must employ interventions that reduce the exposure of human populations to infectious mosquitoes. To this end, numerous anti-malarial drugs are under assessment in a variety of transmission-blocking assays which fail to
Leanna M. Upton +9 more
openalex +7 more sources