Results 101 to 110 of about 33,834 (203)
A Prospective Analysis of Adverse Drug Reactions in a South Indian Hospital [PDF]
, 2009 Adverse drug reactions are a great cause of concern to the medical profession, the patients and the pharmaceutical industry. However ADR reporting and monitoring is yet to catch up in India.
Adhikari, P, Padmaja, U, Pereira, P
core
Knowledge among Drug Dispensers and Antimalarial Drug Prescribing Practices in Public Health Facilities in Dar es Salaam. [PDF]
, 2013 Irrational prescribing and dispensing of antimalarials has been identified as a contributing factor in the emergence of malaria parasites resistant to existing antimalarial drugs.
Kamuhabwa, Appolinary Ar +1 more
core +2 more sources
Fixed drug eruption at a dermatology clinic in Lagos, Nigeria
Journal of Clinical Sciences, 2015 Background: Fixed drug eruption (FDE) is common cutaneous drug eruption characterized by the development of one or more annular, oval, erythematous, and hyperpigmented patches as a result of systemic exposure to a drug.
Olusola Olabisi Ayanlowo
doaj +1 more source
Certain amplified genomic-DNA fragments (AGFs) may be involved in cell cycle progression and chloroquine is found to induce the production of cell-cycle-associated AGFs (CAGFs) in Plasmodium falciparum [PDF]
arXiv, 2015 It is well known that cyclins are a family of proteins that control cell-cycle progression by activating cyclin-dependent kinase. Based on our experimental results, we propose here a novel hypothesis that certain amplified genomic-DNA fragments (AGFs) may also be required for the cell cycle progression of eukaryotic cells and thus can be named as cell ...
arxiv
Drugs in Context, 2019 Several experimental and clinical studies have transformed the traditional antimalarial role of chloroquine (CHQ) and related structural analogues to potent therapeutic agents for a host of nonmalarial indications.
Ashutosh M Shukla, Aparna Wagle Shukla
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 2014 Due to the recent advances of atovaquone, a naphthoquinone, through clinical trials as treatment for malarial infection, 19 quinone derivatives with previously reported structures were also evaluated for blood schizonticide activity against the malaria ...
Nicolli Bellotti de Souza +6 more
doaj +1 more source
Antimalarial drugs and their actions [PDF]
Postgraduate Medical Journal, 1973 SummaryNew antimalarial drugs are required, partly because of the emergence of drug resistant strains of malaria parasites and partly because better compounds are needed to cure relapsing tertian malaria. In reviewing the diverse modes of action of currently used antimalarials, against a background of the pathogenesis of malaria, attention is drawn to ...
openaire +2 more sources
, 2007 Piperaquine is being developed as a long-acting component in artemisinin combination therapies. It was highly active in vitro and drug interaction studies showed that dihydroartemisinin combinations with piperaquine, chloroquine, and amodiaquine were ...
Adagu, Ipemida S +2 more
core +2 more sources
Memorias do Instituto Oswaldo Cruz, 2015 Several species of Aspidospermaplants are used to treat diseases in the tropics, including Aspidosperma ramiflorum, which acts against leishmaniasis, an activity that is experimentally confirmed.
Anna CC Aguiar +5 more
doaj +1 more source
Electrocardiographic safety evaluation of dihydroartemisinin piperaquine in the treatment of uncomplicated falciparum malaria. [PDF]
, 2007 Dihydroartemisinin-piperaquine (DP) could become a leading fixed combination malaria treatment worldwide. Although there is accumulating evidence of efficacy and safety from clinical trials, data on cardiotoxicity are limited.
Ashley, E A +8 more
core +1 more source