Results 121 to 130 of about 91,276 (376)

Thiocarbamoylimidates as Precursors of New 5‐Amino‐1,2,4‐Triazole and Oxadiazole Derivatives In Silico Prediction of Absorption, Distribution, Metabolism, and Excretion Parameters

ChemPlusChem, EarlyView.
1,2,4‐triazole and oxadiazole motifs are synthesized from thiocarbamoylimidates precursors, under mild conditions (40 °C) in the environmentally friendly water/ethanol reaction medium. The reaction is highly versatile and allows for the introduction of a wide variety of functional groups.
Oumaima Gatri, Thierry Roisnel, Marie Cordier, Vincent Dorcet, Mohamed Lotfi Efrit, Cédric Fischmeister   +5 more
wiley   +1 more source

Transition Metal‐Free Ortho‐Deuteration of Electron‐Deficient N‐Heteroarenes

European Journal of Organic Chemistry, EarlyView.
Herin, the metal‐free, selective deuteration of electron‐deficient N‐heteroaromatics is reported using O‐carbamate and carboxamide ortho‐directing groups (DGs), lithium 2,2,6,6‐tetramethylpiperidide as the base, and D2O as a green source of D+. The substrate scope includes 10 small molecule N‐heteroaromatic compounds and two pharmaceutically relevant ...
Žiga Oražem, Luka Jedlovčnik, Jernej Birk, Andrej Pevec, Ross D. Jansen‐van Vuuren, Janez Košmrlj   +5 more
wiley   +1 more source

Intramolecular Hydrogen Bonds in Conformers of Quinine and Quinidine: An HF, MP2 and DFT Study

Molecules, 2017
Quinine is an alkaloid with powerful antimalarial activity, isolated from the bark of Peru’s cinchona trees. Quinidine is an erythro diastereoisomer of quinine also exhibiting antimalarial activity.
Mireille K. Bilonda, Liliana Mammino
doaj   +1 more source

The silent burden of anaemia in Tanzania children:a community-based study [PDF]

, 2003
Objective was to document the prevalence, age-distribution, and risk factors for anaemia in Tanzanian children less than 5 years old,thereby assisting in the development of effective strategies for controlling anaemia.\ud \ud Cluster sampling was used to
Armstrong Schellenberg, J R M, Mbuya, C, Mgalula, L, Mushi, A, Savigny de, D, Schellenberg, D, Victoria, C.G.   +6 more
core   +2 more sources

Engineering Gossypol‐Free Cottonseeds for Future Global Food Security and Agricultural Sustainability

Food Frontiers, EarlyView.
This study depicting the role of transcriptomics, RNA interference (RNAi), and CRISPR/Cas9 technologies in the breeding of glandless cottonseed and glanded cotton tissues. This approach demonstrates the potential of cotton as a dual‐purpose crop, serving both the fiber industry and as a sustainable food and feed source.
Teame Gereziher Mehari, Muhammad Yousaf Shani, Jungfeng Tang, Hui Fang, Muhammad Jawad Umer, Fang Liu, Kai Wang, Dengbing Yao, Muhammad K. R. Khan, Baohua Wang   +9 more
wiley   +1 more source

Knowledge of Malaria and Its Uncomplicated Treatment with Argemone mexicana L. in Selected Districts of Jimma Zone, Oromia Regional State, Ethiopia: A Community-Based Cross Sectional Survey [Corrigendum]

Infection and Drug Resistance, 2022
Tekassa T, Hasen G, Merga H, Cavin AL, Graz B, Suleman S. Infect Drug Resist. 2022;15:3087-3095. Page 3087, Introduction, line 2, the text “4,50,000” should read “450,000”.
Tekassa T, Hasen G, Merga H, Cavin AL, Graz B, Suleman S   +5 more
doaj  

THE INFLUENCE OF POTASSIUM CONCENTRATION ON THE ACTION OF QUINIDINE AND OF SOME ANTIMALARIAL SUBSTANCES ON CARDIAC MUSCLE [PDF]

, 1957
A. K. ARMITAGE
openalex   +1 more source

FIGO good practice recommendations on anemia in pregnancy, to reduce the incidence and impact of postpartum hemorrhage (PPH)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Anemia affects 32 million pregnant women globally, contributing annually to more than 115 000 maternal deaths and 591 000 perinatal deaths worldwide. Low‐ and middle‐income countries (LMICs) bear the highest burden of anemia in pregnancy, with nearly 50% of affected pregnant women. It is now 2025, which is WHO's target year for a 50% reduction
Akaninyene E. Ubom, Ferdousi Begum, Diana Ramasauskaite, Albaro J. Nieto‐Calvache, Monica Oguttu, Inês Nunes, Zechariah J. Malel, Jolly Beyeza‐Kashesya, Alison Wright, on behalf of the FIGO Committee on Childbirth and Postpartum Hemorrhage   +9 more
wiley   +1 more source

New approaches in antimalarial drug discovery and development: a review

Memorias do Instituto Oswaldo Cruz, 2012
Malaria remains a major world health problem following the emergence and spread of Plasmodium falciparum that is resistant to the majority of antimalarial drugs.
Anna Caroline C Aguiar, Eliana MM da Rocha, Nicolli B de Souza, Tanos CC França, Antoniana U Krettli   +4 more
doaj   +1 more source

Antimalarial Activity and Toxicity of a Metabolic Derivative of Quinine [PDF]

, 1946
F. E. Kelsey, Frances K. Oldham, W. Cantrell, E. M. K. Geiling   +3 more
openalex   +1 more source