Retinal toxicity induced by antimalarial drugs: literature review and case report
Medwave, 2016 Los antipalúdicos son fármacos ampliamente utilizados en varios países para el control de enfermedades reumatológicas como el lupus eritematoso sistémico y la artritis reumatoide. En México continúan siendo muy aceptados por su bajo costo y pocos efectos
Manuel Garza-Leon +2 more
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Infection and Drug Resistance, 2022 Tamirat Tekassa,1 Gemmechu Hasen,1 Hailu Merga,2 Anne-Laure Cavin,3 Bertrand Graz,3 Sultan Suleman1 1School of Pharmacy, Institute of Health, Jimma University, Jimma, Oromia Regional State, Ethiopia; 2Department of Epidemiology, Institute of Health ...
Tekassa T +5 more
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Frontiers in Pharmacology, 2023 Due to the outbreak of the SARS-CoV-2 virus, drug repurposing and Emergency Use Authorization have been proposed to treat the coronavirus disease 2019 (COVID-19) during the pandemic. While the efficiency of the drugs has been discussed, it was identified
Seung-Hyun Yoon +6 more
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Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk? [PDF]
, 2009 Current guidelines recommend that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub-Saharan Africa, declining proportions of fevers due to malaria, and the ...
English, Mike +3 more
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Optimal design of experiments by combining coarse and fine measurements [PDF]
Phys. Rev. Lett. 119, 208101 (2017), 2017 In many contexts it is extremely costly to perform enough high quality experimental measurements to accurately parameterize a predictive quantitative model. However, it is often much easier to carry out large numbers of experiments that indicate whether each sample is above or below a given threshold.
arxiv +1 more source
Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline
Microbiology Spectrum, 2023 Malaria, especially Plasmodium falciparum infection, remains an enormous problem, and its treatment and control are seriously challenged by drug resistance. New antimalarial drugs are needed.
Oriana Kreutzfeld +20 more
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Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance [PDF]
, 2013 The biggest threat to the war on malaria is the continued evolution of drug resistance by the parasite. Resistance to almost all currently available antimalarials now exists in Plasmodium falciparum which causes the most suffering among all human malaria
Mwangi, J.M., Ranford-Cartwright, L.C.
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Antiplasmodial activity of p-substituted benzyl thiazinoquinone derivatives and their potential against parasitic infections [PDF]
, 2020 Malaria is a life-threatening disease and, what is more, the resistance to available antimalarial drugs is a recurring problem. The resistance of Plasmodium falciparum malaria parasites to previous generations of medicines has undermined malaria control ...
Basilico, Nicoletta +6 more
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Health-related quality of life and depression among participants in the Sjögren's International Collaborative Clinical Alliance registry. [PDF]
, 2017 ObjectiveTo examine health-related quality of life (HRQoL) and depression among participants in an international Sjögren's syndrome (SS) registry, comparing those with and without SS.MethodsCross-sectional study of participants in the Sjögren's ...
Chou, Annie +5 more
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Characterization of the infectious reservoir of malaria with an agent-based model calibrated to age-stratified parasite densities and infectiousness [PDF]
Malaria Journal 2015, 14:231, 2015 Background Elimination of malaria can only be achieved through removal of all vectors or complete depletion of the infectious reservoir in humans. Mechanistic models can be built to synthesize diverse observations from the field collected under a variety of conditions and subsequently used to query the infectious reservoir in great detail.
arxiv +1 more source