Results 41 to 50 of about 91,276 (376)
Frontiers in Drug Discovery, 2023 More than sesquicentennial years of malarial research, however the unique malarial parasite, Plasmodium still bewilders us with its atypical characteristic features.
Ankita Tehlan +3 more
doaj +1 more source
Adherence to a Six-Dose Regimen of Artemether-Lumefantrine for Treatment of Uncomplicated Plasmodium Falciparum Malaria in Uganda. [PDF]
, 2004 Measuring baseline levels of adherence and identifying risk factors for non-adherence are important steps before the introduction of new antimalarials. In Mbarara in southwestern Uganda, we assessed adherence to artemether-lumefantrine (Coartem) in its ...
Bajunirwe, F +9 more
core +2 more sources
American Journal of Tropical Medicine and Hygiene, 2019 Substandard and falsified medicines pose significant risks to global health, including increased deaths, prolonged treatments, and growing drug resistance.
S. Ozawa +6 more
semanticscholar +1 more source
KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. [PDF]
, 2014 Preventing relapses of Plasmodium vivax malaria through a radical cure depends on use of the 8-aminoquinoline primaquine, which is associated with safety and compliance issues.
Borboa, Rachel +25 more
core +1 more source
Angewandte Chemie, EarlyView.In this study, we repurposed human Aurora kinase‐specific inhibitors to identify potential antimalarial agents. Two inhibitors, hesperadin and TAE684, exhibited sub‐micromolar activity across multiple parasite stages, with hesperadin demonstrating significant potency and selectivity by specifically targeting PfArk1.
Henrico Langeveld +23 more
wiley +2 more sources
Acute Kidney Injury in a Patient Receiving Antimalarial Therapy: A Case Report
Haseki Tıp Bülteni, 2020 In this article, we present a case of Plasmodium falciparum malaria in a male patient who developed acute kidney injury during antimalarial treatment.
Heval Can Bilek +2 more
doaj +1 more source
Requirements for Diagnosis of Malaria at Different Levels of the Laboratory Network in Africa. [PDF]
, 2009 The rapid increase of resistance to cheap, reliable antimalarials, the increasing cost of effective drugs, and the low specificity of clinical diagnosis has increased the need for more reliable diagnostic methods for malaria.
Barnish +5 more
core +1 more source
Antimalarials – are they effective and safe in rheumatic diseases?
Rheumatology, 2018 Antimalarial drugs (AD) are a group of widespread therapeutic agents in multiple rheumatic indications. Although the effect of AD is mild and extended in time, low toxicity is their appreciated value.
E. Haladyj +3 more
semanticscholar +1 more source
A rare case of melanosis of the hard palate mucosa in a patient with chronic myeloid leukemia [PDF]
, 2015 Imatinib Mesylate, also known as Gleevec or ST1-571, is a tyrosine-kinase inhibitor used as the gold standard medication for the chronic myeloid leukemia (CML); Imatinib has indeed deeply revolutionized the CML therapy allowing most patients to have a ...
Bosco, Daniela +4 more
core +3 more sources
The COVID-19 Treatment Landscape: A South African Perspective on a Race Against Time
Frontiers in Medicine, 2021 The pandemic caused by SARS-CoV-2 has infected more than 94 million people worldwide (as of 17 January 2020). Severe disease is believed to be secondary to the cytokine release syndrome (CRS or “cytokine storm”) which causes local tissue damage as well ...
Candice Laverne Hendricks +4 more
doaj +1 more source