Results 71 to 80 of about 54,267 (309)

Multisectoral Convergence of Food, Nutrition and Sanitation Programs for Child Health: Evidence From Country‐Level Programs in India

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This paper underscores the critical role of multisectoral convergence in enhancing child health, particularly in addressing anemia, a micronutrient deficiency linked to both diet and sanitation. We explore how the integration of nationwide food and nutrition programs with sanitation initiatives impacts anemia in Indian children under three ...
Soumya Gupta, Payal Seth, Prabhu Pingali
wiley   +1 more source

Expanding horizons for clinical applications of chloroquine, hydroxychloroquine, and related structural analogues

Drugs in Context, 2019
Several experimental and clinical studies have transformed the traditional antimalarial role of chloroquine (CHQ) and related structural analogues to potent therapeutic agents for a host of nonmalarial indications.
Ashutosh M Shukla, Aparna Wagle Shukla
doaj   +1 more source

The COVID-19 Treatment Landscape: A South African Perspective on a Race Against Time

Frontiers in Medicine, 2021
The pandemic caused by SARS-CoV-2 has infected more than 94 million people worldwide (as of 17 January 2020). Severe disease is believed to be secondary to the cytokine release syndrome (CRS or “cytokine storm”) which causes local tissue damage as well ...
Candice Laverne Hendricks, Candice Herd, Marcel Nel, Gregory Tintinger, Michael Sean Pepper   +4 more
doaj   +1 more source

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 [PDF]

, 2022
Laura E. de Vries, Patrick A.M. Jansen, Catalina Barceló, Justin Munro, Julie M.J. Verhoef, Charisse Flerida A. Pasaje, Kelly Rubiano, Josefine Striepen, Nada Abla, Luuk Berning, Judith M. Bolscher, Claudia Demarta‐Gatsi, Rob Henderson, Tonnie Huijs, Karin M. J. Koolen, Patrick K. Tumwebaze, Tomas Yeo, Anna Caroline Campos Aguiar, Íñigo Angulo‐Barturen, Alisje Churchyard, Jake Baum, Benigno Crespo Fernández, Aline Fuchs, Francisco‐Javier Gamo, Rafael V. C. Guido, Marı́a Belén Jiménez-Dı́az, Dhélio B. Pereira, Rosemary Rochford, Camille Roesch, Laura M. Sanz, Graham Trevitt, Benoît Witkowski, Sergio Wittlin, Roland A. Cooper, Philip J. Rosenthal, Robert W. Sauerwein, Joost Schalkwijk, Pedro H. H. Hermkens, Roger V. Bonnert, Brice Campo, David A. Fidock, Manuel Llinás, Jacquin C. Niles, Taco W. A. Kooij, Koen J. Dechering   +44 more
openalex   +1 more source

Challenges of modeling pristane‐induced lupus in non‐human primates

Animal Models and Experimental Medicine, EarlyView.
Systemic lupus erythematosus (SLE) in cynomolgus monkeys was modeled by two intraperitoneal injections of pristane at a dose of 3.5 mL/kg, administered at weeks 1 and 23. Serum samples from all monkeys that received pristane tested positive for antinuclear antibodies.
Elena Vladimirovna Vinogradova, Maria Alexandrovna Varavko, Yakov Yuryevich Ustyugov, Alexey Alexandrovich Aleksandrov, Dmitry Alexandrovich Khochenkov, Yulia Nikolaevna Linkova   +5 more
wiley   +1 more source

Blood shizonticidal activities of phenazines and naphthoquinoidal compounds against Plasmodium falciparum in vitro and in mice malaria studies

Memorias do Instituto Oswaldo Cruz, 2014
Due to the recent advances of atovaquone, a naphthoquinone, through clinical trials as treatment for malarial infection, 19 quinone derivatives with previously reported structures were also evaluated for blood schizonticide activity against the malaria ...
Nicolli Bellotti de Souza, Isabel M de Andrade, Paula F Carneiro, Guilherme AM Jardim, Isadora MM de Melo, Eufrânio N da Silva Júnior, Antoniana Ursine Krettli   +6 more
doaj   +1 more source

Care-seeking patterns for fatal malaria in Tanzania. [PDF]

, 2004
BACKGROUND\ud \ud Once malaria occurs, deaths can be prevented by prompt treatment with relatively affordable and efficacious drugs. Yet this goal is elusive in Africa.
de Savigny, Don, Kasale, Harun, Masanja, Honorati, Mayombana, Charles, Mbuya, Conrad, Minhaj, Abdulatif, Mkilindi, Yahya, Mwageni, Eleuther, Reid, Graham   +8 more
core   +4 more sources

Study of the Antimalarial Activity of the Leaf Extracts and Fractions of Persea americana and Dacryodes edulis and Their HPLC Analysis [PDF]

, 2021
Philip F. Uzor, Chukwuebuka K. Onyishi, Adaeze P. Omaliko, Somtochukwu A. Nworgu, Onyemaechi H. Ugwu, Ngozi Nwodo   +5 more
openalex   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Fixed drug eruption at a dermatology clinic in Lagos, Nigeria

Journal of Clinical Sciences, 2015
Background: Fixed drug eruption (FDE) is common cutaneous drug eruption characterized by the development of one or more annular, oval, erythematous, and hyperpigmented patches as a result of systemic exposure to a drug.
Olusola Olabisi Ayanlowo
doaj   +1 more source