Polymeric organoiron compounds with carcinostatic properties (branched hydrazone linkers) [PDF]
The insufficient efficaciousness of most currently used anticancer drugs has prompted worldwide efforts to reduce toxic and resistance effects, improve overall bioavailability, and widen the therapeutic window. A particularly promising technology to this
Nkazi, Bavon Diakanua
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Effects of the Protein Kinase Inhibitor PKC412 on Gene Expression and Link to Physiological Effects in Zebrafish Danio rerio Eleuthero-Embryos [PDF]
To identify molecular effects of the antineoplastic agent protein kinase C inhibitor 412 (PKC412) (midostaurin), we applied gene expression profiling in zebrafish using whole-genome microarrays.
Affolter, Markus+5 more
core
A genome scale overexpression screen to reveal drug activity in human cells [PDF]
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Managing Pharmacotherapy in People Living With HIV and Concomitant Malignancy. [PDF]
Objective: To describe data with selected malignancies in people living with HIV (PLWH) and HIV in individuals affected by both conditions and to summarize drug-drug interactions (DDIs) with clinical recommendations for point-of-care review of ...
Chan, Alexandre+3 more
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The standard of care for patients suffering cancer often includes treatment with nucleoside analogues (NAs). NAs are internalized by cell-specific nucleobase/nucleoside transporters and, after enzymatic activation (often one or more phosphorylation steps)
Balzarini, Jan+2 more
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DNA TARGETED ANTHRAQUINONE DERIVATIVES: AN IMPORTANT ANTICANCER AGENTS [PDF]
Deoxyribonucleic acid, DNA is the source of various genetic information and is currently one of the most important and studied biological receptor.
Adhikari, Anupriya+1 more
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Metabolic Reprogramming in Anticancer Drug Resistance: A Focus on Amino Acids [PDF]
Elisa Pardella+4 more
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Capecitabine: guaranteed access in adjuvant treatment of breast cancer. [PDF]
Cachafeiro Pin AI+3 more
europepmc +1 more source
SGLT2 Inhibitors in Mitigating Cancer Therapy-Related Cardiac Dysfunction: Expanding the Evidence. [PDF]
Dabour MS, Blaes AH, Ramu B, Zordoky BN.
europepmc +1 more source
Trends in antineoplastic drug use, cost and prescribing patterns among patients with lung cancer in nine major cities of China, 2016-2020: a retrospective observational study based on inpatient and outpatient hospital data. [PDF]
Shang J+10 more
europepmc +1 more source