Results 51 to 60 of about 7,527 (154)

Early Onset Heart Failure due to RBM20 Variant: A Case Report Emphasizing Genetic Diagnosis and Arrhythmic Risk Stratification

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
Transthoracic echocardiography demonstrating biventricular dilatation. Parasternal long‐ and short‐axis views and apical four‐ and two‐chamber views show marked left ventricular dilatation with increased end‐diastolic volume, associated with right ventricular dilatation.
Cristian Orlando Porras Bueno   +3 more
wiley   +1 more source

Synthesis of Benzopyrans and Quinolines with Nitrogenated Chain and Their Cytotoxicity Against Human Cancer Cell Lines

open access: yesChemMedChem, Volume 21, Issue 2, January 2026.
Natural products and/or their structural analogs represent the greatest number of approved small‐molecules as antitumor agents. We report the synthesis of 2‐propanamide and 2‐propanamine dihydrobenzopyrans and 2‐ and 2,3‐disubstituted quinolines to evaluate their cytotoxicity against human A549 (lung), A2058 (melanoma), HepG2 (liver), MCF‐7 (breast ...
Bernabeu‐Sanchis Álvaro   +8 more
wiley   +1 more source

Using a 3-d model system to screen for drugs effective on solid tumors [PDF]

open access: yes, 2011
There is a large medical need for the development of effective anticancer agents with minimal side effects. The present thesis represents an attempt to identify potent drugs for treatment of solid tumors.
Fayad, Walid
core   +1 more source

Development and Characterization of Copaiba Oil‐Loaded Polymeric Nanocapsules With Enhanced Antitumor Activity Against Breast Cancer Cells

open access: yesParticle &Particle Systems Characterization, Volume 43, Issue 1, January 2026.
The present study developed and characterized a novel copaiba oil polymeric nanoparticle (NPOC), which was efficiently internalized by breast cancer cells, exhibited greater cytotoxicity and selectivity than free copaiba oil and standard drug doxorubicin. NPOC also reduced tumor growth and migration in 3D models.
Karinne Kelly Gadelha Marques   +10 more
wiley   +1 more source

Acute toxicity of novel N-sulfonylpyrimidine derivatives in vivo [PDF]

open access: yes
The aim of the present study was to investigate in vivo toxic effects and to find acute toxic doses (LD 50) of novel N-sulfonyl derivatives of pyrimidine nucleobases uracil and cytosine. Six N-1-sulfonyluracil derivatives (1, 2, 6, 7, 8, and 9) and two N-
Biserka Žinić   +5 more
core  

UA94/6/15 Student / Alumni Personal Papers WKU Dorris Hutchinson [PDF]

open access: yes, 2015
Correspondence and publications created by and about the Dorris Hutchison during her time at Sloan-Kettering ...
WKU Archives
core   +1 more source

Effects of the Protein Kinase Inhibitor PKC412 on Gene Expression and Link to Physiological Effects in Zebrafish Danio rerio Eleuthero-Embryos [PDF]

open access: yes, 2017
To identify molecular effects of the antineoplastic agent protein kinase C inhibitor 412 (PKC412) (midostaurin), we applied gene expression profiling in zebrafish using whole-genome microarrays.
Affolter, Markus   +5 more
core  

Effect of cisplatin in Mytilus galloprovincialis and of cyclophosphamide, tamoxifen and cisplatin on Ca2+ATPase [PDF]

open access: yes, 2015
Relatório de Estágio de Licenciatura, Biologia Marinha, Faculdade de Ciências e Tecnologias da Universidade do Algarve, 2015In the last decade anti-cancer drugs, such as cisplatin, tamoxifen and cyclophosphamide, have seen their use greatly increase ...
Morais, Matilde
core  

Managing Pharmacotherapy in People Living With HIV and Concomitant Malignancy. [PDF]

open access: yes, 2019
Objective: To describe data with selected malignancies in people living with HIV (PLWH) and HIV in individuals affected by both conditions and to summarize drug-drug interactions (DDIs) with clinical recommendations for point-of-care review of ...
Chan, Alexandre   +3 more
core   +1 more source

A Systematic Review of Iran’s Medicinal Plants With Anticancer Effects [PDF]

open access: yes, 2015
Increase in cases of various cancers has encouraged the researchers to discover novel, more effective drugs from plant sources. This study is a review of medicinal plants in Iran with already investigated anticancer effects on various cell lines.
Asadi-Samani, Majid.   +3 more
core   +1 more source

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