Update and new advances in fertility preservation and cancer
CA: A Cancer Journal for Clinicians, Volume 75, Issue 6, Page 602-629, November/December 2025.Abstract Adolescents and young adults with a cancer diagnosis face unique challenges during treatment and into survivorship related to fertility and family building. This review provides an updated overview of the impact of cancer and its associated treatments, including novel treatments in male and female fertility.
Gwendolyn P. Quinn +11 more
wiley +1 more source
Acute toxicity of novel N-sulfonylpyrimidine derivatives in vivo [PDF]
The aim of the present study was to investigate in vivo toxic effects and to find acute toxic doses (LD 50) of novel N-sulfonyl derivatives of pyrimidine nucleobases uracil and cytosine. Six N-1-sulfonyluracil derivatives (1, 2, 6, 7, 8, and 9) and two N-
Biserka Žinić +5 more
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5-Azacytidine and 5-aza-2'-deoxycytidine behave as different antineoplastic agents in B16 melanoma. [PDF]
, 1987 The antiproliferative effects of 5-azacytidine (acaCyd) and 5-aza-2'-deoxycytidine (azadCyd) were studied in murine B16 melanoma and a series of B16 melanoma derived mutant strains with selective resistances to the respective drugs.
Bernheim, J. +3 more
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Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, Volume 599, Issue 21, Page 3150-3162, November 2025.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
UA94/6/15 Student / Alumni Personal Papers WKU Dorris Hutchinson [PDF]
, 2015 Correspondence and publications created by and about the Dorris Hutchison during her time at Sloan-Kettering ...
WKU Archives
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Effect of cisplatin in Mytilus galloprovincialis and of cyclophosphamide, tamoxifen and cisplatin on Ca2+ATPase [PDF]
, 2015 Relatório de Estágio de Licenciatura, Biologia Marinha, Faculdade de Ciências e Tecnologias da Universidade do Algarve, 2015In the last decade anti-cancer drugs, such as cisplatin, tamoxifen and cyclophosphamide, have seen their use greatly increase ...
Morais, Matilde
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Managing Pharmacotherapy in People Living With HIV and Concomitant Malignancy. [PDF]
, 2019 Objective: To describe data with selected malignancies in people living with HIV (PLWH) and HIV in individuals affected by both conditions and to summarize drug-drug interactions (DDIs) with clinical recommendations for point-of-care review of ...
Chan, Alexandre +3 more
core +1 more source
Effects of the Protein Kinase Inhibitor PKC412 on Gene Expression and Link to Physiological Effects in Zebrafish Danio rerio Eleuthero-Embryos [PDF]
, 2017 To identify molecular effects of the antineoplastic agent protein kinase C inhibitor 412 (PKC412) (midostaurin), we applied gene expression profiling in zebrafish using whole-genome microarrays.
Affolter, Markus +5 more
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A Systematic Review of Iran’s Medicinal Plants With Anticancer Effects [PDF]
, 2015 Increase in cases of various cancers has encouraged the researchers to discover novel, more effective drugs from plant sources. This study is a review of medicinal plants in Iran with already investigated anticancer effects on various cell lines.
Asadi-Samani, Majid. +3 more
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Metabolic Imaging to Assess Treatment Response to Cytotoxic and Cytostatic Agents [PDF]
, 2016 For several decades, cytotoxic chemotherapeutic agents were considered the basis of anti-cancer treatment for patients with metastatic tumors. A decrease in tumor burden, assessed by volumetric computed tomography (CT) and magnetic resonance imaging (MRI)
Natalie J. Serkova, S. Gail Eckhardt
core +2 more sources