Results 101 to 110 of about 17,951 (205)

Cisplatin resistance coupled to enhanced sensitivity to metabolic interventions

Molecular & Cellular Oncology, 2018
Specific metabolic alterations have recently been observed in cisplatin-resistant cancers. As a result, cisplatin resistance can be overcome by co-administration of pyridoxine, and cisplatin-resistant cancer cells become exquisitely sensitive to killing ...
Maria Castedo, Florine Obrist, Guido Kroemer   +2 more
doaj   +1 more source

Case series of subconjunctival Inj mitomycin C with bleb massage in postoperative period of mitomycin C augmented trabeculectomies for bleb modulation

Indian Journal of Ophthalmology. Case Reports
We report four cases of use of Inj mitomycin C (MMC) (20 mcg) in the subconjunctival space adjacent to bleb of MMC augmented trabeculectomies, followed by bleb massage regimen.
Anukool S Deshpande, Sushama N Rahate
doaj   +1 more source

Late onset of sequential multifocal bleb leaks after filtration surgery with antimetabolites (5-fluorouracil and mitomycin C)

, 1996
Purpose. Antimetabolites increase the success of filtration surgery but also increase the post-operative complications. We describe the late onset of sequential multifocal bleb leaks as a previously unreported postoperative complication after filtering ...
Belyea, D. A., Dan, J. A., Stamper, R. L., Lieberman, M. F., Spencer, W. H.   +4 more
core  

Protein antimetabolites in legume seed defense

, 1999
215-222The search for insect resistant chemicals in legume seeds has prompted scientists to identity many antimetabolites that impart resistance against many stored product pests.
Ignacimuthu, S
core  

Studies on microbial protein synthesis with Azotobacter vinelandii as the test organism I. Incorporation of radioactive phosphate and sulfate into the resting cells in the presence of antibiotics and antimetabolites

, 1962
The effects of the three antibiotics, chloramphenicol, streptomycin and penicillin and two antimetabolites, p-fluorophenylalanine and 8-azaguanine, on the synthesis of nucleic acid and protein in Azotobacter vinelandii were investigated by studying the ...
Burma, D. P., Chakravorty, Maharani
core   +1 more source

Presence/absence of putative homolog proteins in nine pseudomonad strains infecting Corylus avellana trees.

, 2015
The indication concerns the production of phytotoxins and antimetabolites (A), and antibiotic and lantibiotics (B). Strain legend is shown in Table 1.
Simone Marcelletti (194857), Marco Scortichini (194877)   +1 more
core   +1 more source

Role of Folylpolygutamate Synthetase (FPGS) in Antifolate Chemotherapy; a Biochemical and Clinical Update

, 1996
Even though folate antimetabolites were introduced over forty years ago, they continue to be the backbone of many active chemotherapeutic regimens used by medical and pediatric oncologists.
Barredo, Julio C, Willits, Elizabeth M, Synold, Timothy W   +2 more
core   +1 more source

ANTIMETABOLITES OF SEROTONIN

Journal of Biological Chemistry, 1953
D W, WOOLLEY, E, SHAW
openaire   +2 more sources

A New Electrochemical Sensor for Direct Detection of Purine Antimetabolites and DNA Degradation

, 2019
The development of a reliable electrochemical sensor using a hybrid nanocomposite consisting of ionic liquid (1-butyl-3-methylimidazolium hexafluorophosphate) functionalized graphene oxide (GrO-IL) and gold nanoparticles (AuNPs) stabilized by chitosan ...
Elena Yu. Andryukhina, Liliya K. Shpigun
core   +1 more source

Influence of methylene tetrahydrofolate reductase polymorphisms and coadministration of antimetabolites on toxicity after high dose methotrexate

, 2008
BACKGROUND AND OBJECTIVE: Through interruption of maintenance treatment with 6-mercaptopurine (6MP), toxicity after high-dose methotrexate (HDMTX) may compromise the efficiency of the treatment of children with acute lymphocytic leukaemia (ALL).
Niekerk, P.B. van Kooten, Schmiegelow, K., Schroeder, H.   +2 more
core   +1 more source