Results 101 to 110 of about 16,625 (206)

Leftover mitomycin-c sponge causing blebitis

open access: yesIndian Journal of Ophthalmology, 2019
Trabeculectomy is the commonest surgical intervention performed worldwide for the treatment of open-angle glaucoma. However, the use of antimetabolites during trabeculectomy has been associated with various bleb related complications.
Mayuri Khamar   +3 more
doaj   +1 more source

Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2017
Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. Their uptake into cells depends upon specific transporters; therefore it is essential to establish whether various ...
Khalid J.H. Alzahrani   +7 more
doaj   +1 more source

Long-term follow-up of trabeculectomy without antimetabolites in patients with uveitis

open access: yes, 1999
To determine the long-term success rate after trabeculectomy without antimetabolites in patients with ...
Stavrou, P, Murray, P I; id_orcid
core  

Cisplatin resistance coupled to enhanced sensitivity to metabolic interventions

open access: yesMolecular & Cellular Oncology, 2018
Specific metabolic alterations have recently been observed in cisplatin-resistant cancers. As a result, cisplatin resistance can be overcome by co-administration of pyridoxine, and cisplatin-resistant cancer cells become exquisitely sensitive to killing ...
Maria Castedo   +2 more
doaj   +1 more source

Case series of subconjunctival Inj mitomycin C with bleb massage in postoperative period of mitomycin C augmented trabeculectomies for bleb modulation

open access: yesIndian Journal of Ophthalmology. Case Reports
We report four cases of use of Inj mitomycin C (MMC) (20 mcg) in the subconjunctival space adjacent to bleb of MMC augmented trabeculectomies, followed by bleb massage regimen.
Anukool S Deshpande, Sushama N Rahate
doaj   +1 more source

Computer-assisted microscope analysis of morphonuclear modifications induced by anticancer antimetabolites in cell lines cultured in vitro.

open access: yes, 1994
An original method is proposed for the purpose of discriminating between antimetabolites exhibiting different operating mechanisms. The present work was carried out by means of the digital cell image analysis of Feulgen-stained nuclei cultured in the ...
Atassi, Ghanem   +2 more
core  

A New Electrochemical Sensor for Direct Detection of Purine Antimetabolites and DNA Degradation

open access: yes, 2019
The development of a reliable electrochemical sensor using a hybrid nanocomposite consisting of ionic liquid (1-butyl-3-methylimidazolium hexafluorophosphate) functionalized graphene oxide (GrO-IL) and gold nanoparticles (AuNPs) stabilized by chitosan ...
Elena Yu. Andryukhina, Liliya K. Shpigun
core   +1 more source

Nucleoside and nucleotide analogues containing fluorine [PDF]

open access: yes, 1993
The work contained in this thesis is divided into four sections detailing the formation of (diethoxyphosphinyl)difluoromethylene substituted cycloalkanes and alkenes and their chemistry, as well as the syntheses of purine and pyrimidine substituted ...
Parkinson, Nigel Christopher
core  

Abstract 3069: The S-phase checkpoint function of MGMT provides an unexpected rational route to profoundly increase the efficacy of anticancer antimetabolites in cell culture and xenograft models

open access: yes, 2017
MGMT is an anti-mutagenic DNA repair protein highly expressed not only in brain tumors, but also breast cancers, melanoma and colon cancers, and confers drug resistance.
AGM Mostofa   +4 more
core   +1 more source

REPRODUCTION CONTROL OF DACUS OLEAE USING ANTIMETABOLITES

open access: yes, 1996
ΤΑ ΑΝΑΛΟΓΑ ΑΜΙΝΟΞΕΩΝ ΕΙΝΑΙ ΟΥΣΙΕΣ (ΦΥΣΙΚΕΣ Η ΣΥΝΘΕΤΙΚΕΣ) ΜΕ ΠΑΡΟΜΟΙΑ ΧΗΜΙΚΗ ΔΟΜΗ ΚΑΙ ΔΡΑΣΗ ΜΕ ΤΑ ΚΑΝΟΝΙΚΑ ΑΜΙΝΟΞΕΑ ΤΑ ΟΠΟΙΑ ΚΑΙ ΑΝΤΑΓΩΝΙΖΟΝΤΑΙ, ΕΜΠΟΔΙΖΟΝΤΑΣΤΟ ΜΕΤΑΒΟΛΙΣΜΟ ΤΟΥΣ ΚΑΙ ΠΡΟΚΑΛΩΝΤΑΣ ΣΥΝΗΘΩΣ ΑΡΝΗΤΙΚΑ ΑΠΟΤΕΛΕΣΜΑΤΑ ΣΤΗ ΦΥΣΙΟΛΟΓΙΑ ΤΩΝ ΟΡΓΑΝΙΣΜΩΝ.
Ζωγράφου, Ελένη
core   +1 more source

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