Results 111 to 120 of about 16,625 (206)
Purpose. Antimetabolites increase the success of filtration surgery but also increase the post-operative complications. We describe the late onset of sequential multifocal bleb leaks as a previously unreported postoperative complication after filtering ...
Belyea, D. A. +4 more
core
Antimetabolites in the treatment of arthritis:current status of the use of antimetabolites
Rheumatoid arthritis (RA) is an autoimmune disease characterized by a chronic inflammation of the synovial joints and infiltration of blood-derived cells. In daily practice rheumatologists use the antimetabolites methotrexate (MTX) and leflunomide for the treatment of patients with rheumatoid arthritis.
Dijkmans, B A C, Jansen, G
openaire +2 more sources
A rational approach to chemotherapy : the history of antimetabolites (1935-1955)
En 1940, le biochimiste anglais Donald Woods propose une explication du mode d'action des nouveaux sulfamides antibactériens : l'inhibition compétitive. Son collègue Paul Fildes fonde sur cette base une nouvelle approche de la chimiothérapie, revendiquée
Serviant-Fine, Thibaut
core
The effects of the three antibiotics, chloramphenicol, streptomycin and penicillin and two antimetabolites, p-fluorophenylalanine and 8-azaguanine, on the synthesis of nucleic acid and protein in Azotobacter vinelandii were investigated by studying the ...
Burma, D. P., Chakravorty, Maharani
core +1 more source
Sequential versus Combined Glaucoma and Cataract Procedures in Siriraj Hospital
Objective: To compare the efficacy of intraocular pressure (IOP) control after combined cataract and trabeculectomy with sequential cataract surgery after trabeculectomy, both with and without antimetabolites.
Darin Sakiyalak +2 more
doaj
Targeting the Leloir Pathway with Galactose-Based Antimetabolites in Glioblastoma
Background: Glioblastoma (GBM) uses Glut3 and/or Glut14 and the Leloir pathway to catabolize D-Galactose (Gal). UDP-4-deoxy-4-fluorogalactose (UDP-4DFG) is a potent inhibitor of the two key enzymes, UDP-galactose-4-epimerase (GALE) and UDP-Glucose 6 ...
Alexandra M. Baskin +5 more
core +1 more source
BACKGROUND AND OBJECTIVE: Through interruption of maintenance treatment with 6-mercaptopurine (6MP), toxicity after high-dose methotrexate (HDMTX) may compromise the efficiency of the treatment of children with acute lymphocytic leukaemia (ALL).
Niekerk, P.B. van Kooten +2 more
core
A Study of Efficacy of Intraoperative Application of Mitomycin-C in Endoscopic Dacryocystorhinostomy
Introduction Common cause for failure of endonasal dacryocystorhinostomy is closure of the intranasal ostium usually due to granulation tissue formation.
Harikesh Sharma, Ajay Mallick
doaj
Thirty-three eyes of 33 patients were prospectively evaluated to study the short term efficacy, safety, and overall surgical outcome of initial trabeculectomy for primary glaucomas with adjunctive intraoperative or postoperative 5-Fluorouracil (5-FU) use.
Lamba P, Pandey P, Raina U, Krishna V
doaj

