Results 111 to 120 of about 16,625 (206)

Late onset of sequential multifocal bleb leaks after filtration surgery with antimetabolites (5-fluorouracil and mitomycin C)

open access: yes, 1996
Purpose. Antimetabolites increase the success of filtration surgery but also increase the post-operative complications. We describe the late onset of sequential multifocal bleb leaks as a previously unreported postoperative complication after filtering ...
Belyea, D. A.   +4 more
core  

ANTIMETABOLITES OF SEROTONIN

open access: yesJournal of Biological Chemistry, 1953
D W, WOOLLEY, E, SHAW
openaire   +2 more sources

Antimetabolites in the treatment of arthritis:current status of the use of antimetabolites

open access: yesNucleosides, nucleotides & nucleic acids, 2004
Rheumatoid arthritis (RA) is an autoimmune disease characterized by a chronic inflammation of the synovial joints and infiltration of blood-derived cells. In daily practice rheumatologists use the antimetabolites methotrexate (MTX) and leflunomide for the treatment of patients with rheumatoid arthritis.
Dijkmans, B A C, Jansen, G
openaire   +2 more sources

A rational approach to chemotherapy : the history of antimetabolites (1935-1955)

open access: yes, 2016
En 1940, le biochimiste anglais Donald Woods propose une explication du mode d'action des nouveaux sulfamides antibactériens : l'inhibition compétitive. Son collègue Paul Fildes fonde sur cette base une nouvelle approche de la chimiothérapie, revendiquée
Serviant-Fine, Thibaut
core  

Studies on microbial protein synthesis with Azotobacter vinelandii as the test organism I. Incorporation of radioactive phosphate and sulfate into the resting cells in the presence of antibiotics and antimetabolites

open access: yes, 1962
The effects of the three antibiotics, chloramphenicol, streptomycin and penicillin and two antimetabolites, p-fluorophenylalanine and 8-azaguanine, on the synthesis of nucleic acid and protein in Azotobacter vinelandii were investigated by studying the ...
Burma, D. P., Chakravorty, Maharani
core   +1 more source

Sequential versus Combined Glaucoma and Cataract Procedures in Siriraj Hospital

open access: yesSiriraj Medical Journal, 2006
Objective: To compare the efficacy of intraocular pressure (IOP) control after combined cataract and trabeculectomy with sequential cataract surgery after trabeculectomy, both with and without antimetabolites.
Darin Sakiyalak   +2 more
doaj  

Targeting the Leloir Pathway with Galactose-Based Antimetabolites in Glioblastoma

open access: yes
Background: Glioblastoma (GBM) uses Glut3 and/or Glut14 and the Leloir pathway to catabolize D-Galactose (Gal). UDP-4-deoxy-4-fluorogalactose (UDP-4DFG) is a potent inhibitor of the two key enzymes, UDP-galactose-4-epimerase (GALE) and UDP-Glucose 6 ...
Alexandra M. Baskin   +5 more
core   +1 more source

Influence of methylene tetrahydrofolate reductase polymorphisms and coadministration of antimetabolites on toxicity after high dose methotrexate

open access: yes, 2008
BACKGROUND AND OBJECTIVE: Through interruption of maintenance treatment with 6-mercaptopurine (6MP), toxicity after high-dose methotrexate (HDMTX) may compromise the efficiency of the treatment of children with acute lymphocytic leukaemia (ALL).
Niekerk, P.B. van Kooten   +2 more
core  

A Study of Efficacy of Intraoperative Application of Mitomycin-C in Endoscopic Dacryocystorhinostomy

open access: yesBengal Journal of Otolaryngology and Head Neck Surgery, 2018
Introduction Common cause for failure of endonasal dacryocystorhinostomy is closure of the intranasal ostium usually due to granulation tissue formation.
Harikesh Sharma, Ajay Mallick
doaj  

Short-term results of initial trabeculectomy with intraoperative or postoperative 5-fluorouracil for primary glaucomas

open access: yesIndian Journal of Ophthalmology, 1997
Thirty-three eyes of 33 patients were prospectively evaluated to study the short term efficacy, safety, and overall surgical outcome of initial trabeculectomy for primary glaucomas with adjunctive intraoperative or postoperative 5-Fluorouracil (5-FU) use.
Lamba P, Pandey P, Raina U, Krishna V
doaj  

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