Results 81 to 90 of about 32,473 (237)

Antimetabolites: established cancer therapy.

Journal of Cancer Research and Therapeutics, 2012
Cell death has been divided into two main types: programmed cell death, in which the cell plays an active role, and passive (necrotic) cell death. Senescence arrest, accelerated senescence and differentiation are also responses that can be induced in ...
M. Tiwari
semanticscholar   +1 more source

Pan‐European Fragile Populations Cohort for COVID‐19: What Worked, What Didn't, and Lessons Learned

Transplant Infectious Disease, EarlyView.
ABSTRACT The COVID‐19 pandemic exposed the vulnerability of immunocompromised hosts and the scarcity of evidence guiding their management. Within the European Horizon 2020 ORCHESTRA project, a multinational consortium connected existing and new cohorts to harmonize data, laboratory methods, and clinical expertise across fragile populations. The fragile
Beatrice Tazza, Cecilia Bonazzetti, Natascia Caroccia, Michela Di Chiara, Lorenzo Maria Canziani, Anna Maria Azzini, Zaira R. Palacios‐Baena, Paula Olivares‐Navarro, Jesús Rodríguez‐Baño, Evelina Tacconelli, Pierluigi Viale, Maddalena Giannella   +11 more
wiley   +1 more source

A New Class of Antimetabolites: Pyridine Thioglycosides as Potential Anticancer Agents

Zeitschrift für Naturforschung C - A Journal of Biosciences, 2010
The present study was designed for highlighting and focusing on the cytotoxic activity of a new class of antimetabolites both on human cell lines, namely liver carcinoma cell line (Hepg2), lung carcinoma cell line (H460), breast carcinoma cell line (MCF7)
G. Elgemeie, E. Mahdy, M. A. Elgawish, Mohammad M. Ahmed, W. Shousha, M. E. Eldin   +5 more
semanticscholar   +1 more source

Donor–Recipient Epstein–Barr Virus Serostatus and Time‐Varying Risk of Posttransplant Lymphoproliferative Disorder in Kidney Transplant Recipients

Transplant Infectious Disease, EarlyView.
In a national US kidney transplant cohort, posttransplant lymphoproliferative disorder risk varied dynamically by donor–recipient Epstein–Barr virus serostatus. Donor‐positive/recipient‐negative recipients had the highest sustained risk, while donor‐negative/recipient‐negative recipients faced previously under‐recognized early risk, with PTLD strongly ...
Christie Rampersad, Seyed M. Hosseini‐Moghaddam, S. Joseph Kim   +2 more
wiley   +1 more source

The Role of Belatacept‐Use and Senescence on Infectious and Mortality Complications After Kidney Transplantation

Transplant Infectious Disease, EarlyView.
ABSTRACT Introduction Studies evaluating the incidence of infections after belatacept as a substitute for calcineurin inhibitors (CNI) or antimetabolite in kidney transplant (KT) yielded conflicting results. We compared infectious outcomes after belatacept‐use to no belatacept‐use in KT recipients.
Hareesh Singam, Abdinoor Abdi, Wyatt Tarter, Ben Langworthy, Adam Bregman, Karam M. Obeid   +5 more
wiley   +1 more source

Antimetabolite

, 2008
Citation: 'antimetabolite' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.A00398 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
  +4 more sources

Silver nanoparticles induce reactive oxygen species-mediated cell cycle delay and synergistic cytotoxicity with 3-bromopyruvate in Candida albicans, but not in Saccharomyces cerevisiae

International Journal of Nanomedicine, 2019
Bokyoung Lee,1,2 Mi Jin Lee,1 Su Jin Yun,1,2 Kyongmin Kim,1,2 In-Hong Choi,3 Sun Park1,21Department of Microbiology, Ajou University School of Medicine, Suwon, 442-749, Republic of Korea; 2Department of Biomedical Sciences, The Graduate School,
Lee B, Lee MJ, Yun SJ, Kim K, Choi IH, Park S   +5 more
doaj  

Pyrimidine biosynthesis is not an essential function for trypanosoma brucei bloodstream forms [PDF]

, 2013
<p>Background: African trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host, but it is unknown whether either process is essential to the parasite.</p> <p>Methodology/Principal ...
A Hofer, Anne Donachie, B Aronow, B Rodenko, BA Fox, Ben L. Kelly, CC Wang, D Bi, Daniel N. A. Tagoe, DB Longley, DJ Hammond, ET Larson, G Gao, G Priotto, H Hirumi, Harry P. de Koning, HF Hassan, HMS Ibrahim, HP De Koning, HP De Koning, HP De Koning, HP De Koning, HP De Koning, HP De Koning, IG Papageorgiou, JA Ali, Jane C. Munday, JB French, Juma A. M. Ali, K Van Dyke, KL Martin, Liam J. Morrison, LJ Wallace, M Balasegaram, M Berg, M Berg, MD Scahill, MI Al-Salabi, MJ Natto, MK Gould, N Sienkiewicz, N Sternberg, PI Fields, R Brun, R Brun, S Gudin, S Lillico, SM Landfear, TL Arakaki, V Bellofatto, VM Castillo-Acosta, ZN Wilson   +51 more
core   +4 more sources

Exploring Affordable Curative Therapy for Sickle Cell Disease in Africa: A Comprehensive Overview

American Journal of Hematology, Volume 101, Issue S1, Page 56-74, April 2026.
ABSTRACT The practical aspects of developing curative treatments for sickle cell disease (SCD) in Africa, such as gene therapy and hematopoietic stem cell transplantation, involve strengthening healthcare infrastructure, training healthcare professionals, establishing regional treatment centers, and creating national SCD programs.
Adetola A. Kassim, Alexis A. Thompson, Punam Malik   +2 more
wiley   +1 more source

Escape tardío de la bula de filtración a propósito de un caso Late onset of leaking filtering bleb in a case

Revista Cubana de Oftalmología, 2012
Paciente masculino de 48 años, de color de la piel mestizo, al que se le realizó trabeculectomía con antimetabolito en su ojo derecho con daño glaucomatoso avanzado y atrofia óptica glaucomatosa en su ojo izquierdo.
Yuderkys Díaz Águila, María Teresa Ferrer Guerra, Isabel Obret Mendive, Liamet Fernández Argones, Ibraín Piloto Díaz   +4 more
doaj