Results 21 to 30 of about 90,280 (287)
Small Cationic Peptides: Influence of Charge on Their Antimicrobial Activity
ACS Omega, 2018 The first stage of the action mechanism of small cationic peptides with antimicrobial activity is ruled by electrostatic interactions between the peptide and the pathogen cell membrane. Thus, an increase in its activity could be expected with an increase
J. L. López Cascales +5 more
semanticscholar +1 more source
In Silico Structural Evaluation of Short Cationic Antimicrobial Peptides
Pharmaceutics, 2018 Cationic peptides with antimicrobial properties are ubiquitous in nature and have been studied for many years in an attempt to design novel antibiotics.
Ilaria Passarini +3 more
doaj +1 more source
Nano letters (Print), 2021 Antimicrobial peptides that target the integrity of bacterial envelopes can eradicate pathogens with little development of resistance, but they often inflict nonselective toxicity toward mammalian cells.
Dicky Pranantyo +6 more
semanticscholar +1 more source
Antimicrobial activity and synergistic effect of phage-encoded antimicrobial peptides with colistin and outer membrane permeabilizing agents against Acinetobacter baumannii [PDF]
PeerJBackground Acinetobacter baumannii poses a significant public health threat. Phage-encoded antimicrobial peptides (AMPs) have emerged as promising candidates in the battle against antibiotic-resistant A. baumannii. Methods Antimicrobial peptides from the
Punnaphat Rothong +9 more
doaj +2 more sources
Recent advances in the field of antimicrobial peptides in inflammatory diseases
Advanced Biomedical Research, 2013 Antimicrobial peptides are cationic molecules, which participate in multiple aspects of the immune response including the control of inflammatory diseases, characteristic that make these molecules attractive as therapeutic tools.
Patricia Méndez-Samperio
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Engineering Approaches for the Development of Antimicrobial Peptide-Based Antibiotics
Antibiotics, 2022 Antimicrobial peptides (AMPs) have received increasing attention as potential alternatives for future antibiotics because of the rise of multidrug-resistant (MDR) bacteria.
Su-Jin Kang, So Hee Nam, Bong-Jin Lee
doaj +1 more source
Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides
Frontiers in Microbiology, 2013 Cationic antimicrobial peptides (AMPs) and host defense peptides (HDPs) show vast potential as peptide-based drugs. Great effort has been made in order to exploit their mechanisms of action, aiming to identify their targets as well as to enhance their ...
Kelly eMulder +4 more
doaj +1 more source
Aggregate, 2023 Antimicrobial peptides (AMPs) are potentially powerful alternatives to conventional antibiotics in combating multidrug resistance, given their broad spectrum of activity.
Bruce Lin +14 more
semanticscholar +1 more source
Small cationic antimicrobial peptides delocalize peripheral membrane proteins [PDF]
Proceedings of the National Academy of Sciences, 2014 Significance Multidrug-resistant bacteria present an acute problem to medicine, generating interest in novel antimicrobial strategies. Antimicrobial peptides currently are being investigated, both as antibiotics and as immunomodulatory agents. Many antimicrobial peptides interact with the bacterial membrane, a previously underexplored
Michaela, Wenzel +17 more
openaire +2 more sources
Pharmaceuticals, 2013 Tryptophan and arginine-rich cyclic hexapeptides of the type cyclo-RRRWFW combine high antibacterial activity with rapid cell killing kinetics, but show low toxicity in human cell lines.
Margitta Dathe +4 more
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