Results 201 to 210 of about 262,820 (287)

AI-driven antimicrobial peptide characterization unveils novel motifs for drug design. [PDF]

Sci Rep
Padi S, Mondal K, Hoogerheide DP, Heinrich F, Mihailescu M, Klauda JB, Cardone A.   +6 more
europepmc   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Isolation and partial characterization of antimicrobial peptide-enriched fractions from Parabacteroides distasonis. [PDF]

Sci Rep
Oliveira AGG, Haq IU, de Oliveira PL, de Oliveira JS, Bemquerer MP, Magalhães PP, de Macêdo Farias L.   +6 more
europepmc   +1 more source

Polyphenol‐Based Biomaterials Against Cancer Radio/Chemotherapy‐Induced Intestinal Toxicity

Advanced NanoBiomed Research, EarlyView.
Radiotherapy/chemotherapy often causes intestinal toxicity, impairing cancer patients’ quality of life and treatment efficacy. Polyphenols protect against this injury via multiple mechanisms, but face oral use limitations. This review outlines their protective mechanisms and delivery challenges, highlighting recent oral delivery advances and future ...
Jixu Lu, Jing Chen, Ji Zhu, Lixin Ru, Dongxiao Zhang   +4 more
wiley   +1 more source

AMP-CapsNet: a multi-view feature fusion approach for antimicrobial peptide prediction using capsule networks. [PDF]

Genomics Inform
Ghulam A, Rehman M, Fida H, Zhao PY, Noroze R, Qi YC, Yu XL.   +6 more
europepmc   +1 more source

Comparing the genetic and serum expression of LL-37 Antimicrobial Peptide in pemphigus vulgaris and pemphigus foliaceus patients. [PDF]

An Bras Dermatol
Dhaffouli F, Elloumi N, Sellami K, Bahloul E, Tahri S, Turki H, Hachicha H, Abida O.   +7 more
europepmc   +1 more source

Effects of an antimicrobial peptide on transport- and novel environment-induced stress in British Shorthair cats. [PDF]

Front Vet Sci
Chen S, Zhang M, Yan H, Ye L, Xue Q, Wu Y, Zhao K, Jiang Y, Wang Q, Zhu J, Guo Y, Liu Q, Deng B, Zhang L.   +13 more
europepmc   +1 more source

Potential Molecular Targets of the Broad-Range Antimicrobial Peptide Tyrothricin in the Apicomplexan Parasite Toxoplasma gondii. [PDF]

Biomedicines
Amdouni Y, Boubaker G, Müller J, Sousa MCF, Hänggeli KPA, Uldry AC, Braga-Lagache S, Heller M, Hemphill A.   +8 more
europepmc   +1 more source

Breaking disulfide bonds in a weakly bactericidal α-defensin unleashes a potent antimicrobial peptide with an altered conformation. [PDF]

PLoS Pathog
Luo G, Zhao M, Wang Q, Zhou Y, Yao D, Zhang J, Wang G, Zhang J, Liao C, Lu W.   +9 more
europepmc   +1 more source

Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides

Angewandte Chemie International Edition, EarlyView.
Halogenated and glycosylated 4‐amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) exhibit potent antiplasmodial activity (IC50 = 25–161 nM) against drug‐sensitive and resistant Plasmodium falciparum strains. ABSTRACT 4‐Amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) represent a structurally distinctive family of ...
Hartono Candra, Xue‐Jiao Wang, Ka Diam Go, Li Feng, Miaomiao Cai, Guang‐Lei Ma, Clarissa Widyantoro, Lik Tong Tan, Zbynek Bozdech, Zhe Wang, Zhao‐Xun Liang   +10 more
wiley   +1 more source