Results 221 to 230 of about 1,018,087 (252)

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Evaluation of Antimicrobial Peptide-Antibiotic Combination Treatment for Tackling Ocular and Systemic <i>Staphylococcus aureus</i> Infections. [PDF]

Int J Mol Sci
Barahim EK, Smith EP, Yong ST, Aung TT, Lakshminarayanan R, Mohammed I, Dua HS, Wallace GR, Hombrebueno JR, Rauz S, Ting DSJ.   +10 more
europepmc   +1 more source

Urogenital Infection Risk Associated With SGLT2 Inhibitors Versus DPP‐4 Inhibitors in Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Target Trial Emulation

Clinical Pharmacology &Therapeutics, EarlyView.
Although sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are recommended for patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), concerns regarding urogenital infections persist. Therefore, we evaluated the risk of urinary tract infection (UTI) and genital tract infection (GTI) after SGLT2i initiation in this population ...
Young‐Mi Ah, Junsung Nam, Jung Wook Youn, Yun Mi Yu, Soyoung Kang   +4 more
wiley   +1 more source

Machine Learning Prediction and Experimental Validation of Antimicrobial Peptide Activity Differences against Gram-Positive and Gram-Negative Bacteria. [PDF]

ACS Omega
Lu P, Li W, Zubair M, Li L, Han G, Chu Y.   +5 more
europepmc   +1 more source

Morphological signatures of bacteria‐laden drying droplets: A multimodal analysis across host fluids

Droplet, EarlyView.
Drying patterns of bacteria‐laden droplets encode concentration‐dependent signatures across three host fluids: serum, urine, and nutrient medium. By integrating time‐evolving texture descriptors, image features, and interpretable multimodal machine learning, this study demonstrates a label‐free approach for extracting information on bacterial ...
Anusuya Pal, Amalesh Gope, Piyush Thakur, Gen Honda, Emi Hada, Satoshi Sawai, Miho Yanagisawa   +6 more
wiley   +1 more source

Identification of intracellular target of antimicrobial peptide EWAMP-R in bacteria. [PDF]

Commun Biol
Wu Y, Tang H, Hao P, Xu Y, Zhang Y, Wang M, Jiang R, Jiang J, Zhao Q, Li Y.   +9 more
europepmc   +1 more source

AMPSeek: A Workflow for Predicting Antimicrobial Peptide Activity, Three-Dimensional Structure, and Toxicity. [PDF]

Curr Protoc
Zhang E, Ucar B, Salehi A, Warren RL, Birol I.   +4 more
europepmc   +1 more source

Bacterial cell fate under stress: lipid remodeling and antimicrobial peptide attack. [PDF]

NPJ Antimicrob Resist
Vejzovic D, Schwaiger T, Topciu A, Petrowitsch L, Arnautovic A, Malanovic N.   +5 more
europepmc   +1 more source

Antimicrobial peptide CAP18 as a natural alternative to antibiotics: effects on gut health, immunity, and meat quality in broiler chickens. [PDF]

BMC Vet Res
Jebalbarezi P, Afsharmanesh M, Lohrasbi-Nejad A, Salarmoini M, Bami MK.   +4 more
europepmc   +1 more source

Antifungal activity of the antimicrobial peptide RP557 against priority fungal pathogens. [PDF]

Microbiology (Reading)
Poester VR, Xavier MO, Hidalgo JED, Dos Santos MC, Trápaga MR, Al-Hatmi AMS, Jaynes J, Stevens DA.   +7 more
europepmc   +1 more source