Antimicrobial Peptide Nanomaterials
Antimicrobial peptides exist throughout nature and are produced by multicellular organisms as a defence mechanism against pathogenic microbes. Multi-drug resistant bacteria pose a serious threat to public health. In the increasing absence of new antibiotic agents, there is a need for the development of novel strategies to target bacterial infections ...
Coulter, Sophie, Laverty, Garry
openaire +3 more sources
Analysis and Prediction of some Histone-derived Antimicrobial Peptides from Toads Duttaphrynus melanostictus and Phyrinoidis asper [PDF]
Antimicrobial peptides in skin secretions of toads is a promising methods to combat a wide spectrum of bacteria. Histone H2A is a type of DNA-binding protein that acts as a precursor for several antimicrobial peptides. In toads (family Bufonidae) buforin
Muhammad Dailami +2 more
doaj +1 more source
Antimicrobial Peptides in Action [PDF]
Molecular dynamics simulations of the magainin MG-H2 peptide interacting with a model phospholipid membrane have been used to investigate the mechanism by which antimicrobial peptides act. Multiple copies of the peptide were randomly placed in solution close to the membrane.
Leontiadou, H. +2 more
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Hydrocarbon Stapled Antimicrobial Peptides [PDF]
Abstract Antimicrobial peptides are promising candidates for anti-infective pharmaceuticals. Unfortunately, because of their low proteolytic and chemical stability, their usage is generally narrowed down to topical formulations. Until now, numerous approaches to increase peptide stability have been proposed.
Dorian Migoń +2 more
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In silico structural evaluation of short cationic antimicrobial peptides [PDF]
© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).Cationic peptides with ...
Malkinson, John +3 more
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Targeting Multidrug Resistance With Antimicrobial Peptide-Decorated Nanoparticles and Polymers
As a category of small peptides frequently found in nature, antimicrobial peptides (AMPs) constitute a major part of the innate immune system of various organisms. Antimicrobial peptides feature various inhibitory effects against fungi, bacteria, viruses,
Solmaz Maleki Dizaj +6 more
doaj +1 more source
Design and evaluation of tadpole-like conformational antimicrobial peptides
Antimicrobial peptides are promising alternatives to conventional antibiotics. Herein, we report a class of “tadpole-like” peptides consisting of an amphipathic α-helical head and an aromatic tail.
Ziyi Tang +13 more
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Application of Artificial Intelligence Algorithms in the Field of Antimicrobial Peptide Prediction [PDF]
Antimicrobial peptides, as small molecular peptides with extensive antibacterial activity, have shown great potential in food preservation and other fields because of their unique antibacterial mechanism.
QIAN Yuchen, NIE Ting, HUA Yanming, XU Shiying, GUO Sheng, ZHANG Xin, LUO Xiaohu, LIU Yanan
doaj +1 more source
Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity. [PDF]
Peptide-based supramolecular assemblies are a promising class of nanomaterials with important biomedical applications, specifically in drug delivery and tissue regeneration.
Adler-Abramovich, Lihi +10 more
core +3 more sources
Cn-AMP2 from green coconut water is an anionic anticancer peptide [PDF]
Globally, death due to cancers is likely to rise to over 20 million by 2030,which has created an urgent need for novel approaches to anticancer therapies such as the development of host defence peptides.
Al-Benna +56 more
core +1 more source

