Results 171 to 180 of about 1,502,924 (201)
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Antimutagenic activity of the novel antileukemic agents, avarone and avarol
Mutation Research Letters, 1985The two antileukemic agents, avarone and avarol, were determined to be neither direct nor indirect mutagenic agents in the Ames microsomal test. Moreover, the two sesquiterpenoid compounds drastically reduced the mutagenic effect of benzo[a]pyrene in the same system.
B, Kurelec +5 more
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Antimutagens as cancer chemopreventive agents in the diet
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1994It has been suggested that the use of antimutagens and anticarcinogens in everyday life will be the most effective procedure for preventing human cancer and genetic disease. There are several ways in which mutagenesis can be reduced or prevented. Chemicals which act to interfere with DNA repair or with mutagen metabolism can be effective antimutagens ...
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Journal of Inorganic and Organometallic Polymers and Materials, 2021
This study investigated the microbial synthesis of Ag/AgCl nanoparticles, their mutagenicity, antimutagenicity and antibacterial effects. For this purpose, bacteria isolates were taken from soil samples of Zarshouran gold mine. One silver resistant bacterial strain was selected for the production of silver nanoparticles.
Somayeh Nikouharf Fakher +1 more
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This study investigated the microbial synthesis of Ag/AgCl nanoparticles, their mutagenicity, antimutagenicity and antibacterial effects. For this purpose, bacteria isolates were taken from soil samples of Zarshouran gold mine. One silver resistant bacterial strain was selected for the production of silver nanoparticles.
Somayeh Nikouharf Fakher +1 more
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Antimutagenic Agents from Natural Products of Terrestrial and Marine Origin
1993Both chemists and biologists have been intrigued for many years by the role of secondary metabolites in plants of terrestrial and marine origins. Of equal interest is whether such compounds have antitumor, antiviral, or antimutagenic properties. For example, the highly active antitumor agents, camptothecin and taxol, have been isolated from the bark ...
M E, Wall, M C, Wani
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2004
Porphyrins and their metal derivatives are strong DNA binders with association constants of 10(5) M(-1) to 10(7) M(-1). Some of these compounds have been used for radiation sensitization therapy of cancer and are targeted to interact with cellular DNA.
Heidar-Ali, Tajmir-Riahi +2 more
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Porphyrins and their metal derivatives are strong DNA binders with association constants of 10(5) M(-1) to 10(7) M(-1). Some of these compounds have been used for radiation sensitization therapy of cancer and are targeted to interact with cellular DNA.
Heidar-Ali, Tajmir-Riahi +2 more
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1986
The reproduction and maintenance of identity of species are biological imperatives, and it is not surprising that there exist mechanisms to minimize or repair the deleterious influence of noxious chemicals in the environment on DNA. Animals tend to defend themselves through the use of enzymes which intercept aggressive chemicals and convert them to ...
L A, Mitscher +4 more
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The reproduction and maintenance of identity of species are biological imperatives, and it is not surprising that there exist mechanisms to minimize or repair the deleterious influence of noxious chemicals in the environment on DNA. Animals tend to defend themselves through the use of enzymes which intercept aggressive chemicals and convert them to ...
L A, Mitscher +4 more
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Therapie, 2003
Antimutagens and anticarcinogens are natural or synthetic substances able to inhibit or to reduce spontaneous or induced DNA alteration. These inhibitors act at different levels from the penetration of the xenobiotic to the expression of the mutation and cancer. They act in extracellular and intracellular levels; they react directly with mutagens or on
R, el Hamss, M, Idaomar
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Antimutagens and anticarcinogens are natural or synthetic substances able to inhibit or to reduce spontaneous or induced DNA alteration. These inhibitors act at different levels from the penetration of the xenobiotic to the expression of the mutation and cancer. They act in extracellular and intracellular levels; they react directly with mutagens or on
R, el Hamss, M, Idaomar
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Natural antimutagenic agents may prolong efficacy of human immunodeficiency virus drug therapy
Medical Hypotheses, 1997The long-term efficacy of new combination drug therapies for human immunodeficiency virus infection may be limited by the tendency of transfected human immunodeficiency virus to mutate to drug-resistant forms. This argues for the use of safe antimutagenic measures as adjuvants to such therapies.
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Antimutagenic effects of 2(3)-tert-butyl-4-hydroxyanisole and of antimicrobial agents.
Cancer research, 1979Administration of the antioxidants 2(3)-tert-butyl-4-hydroxyanisole (BHA) and ethoxyquin (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline) with the diet resulted in a marked decrease in the levels of mutagens present in mice treated with benzo(a)pyrene.
R P, Batzinger, S Y, Ou, E, Bueding
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Naturally Occurring Antimutagenic and Cytoprotective Agents
1999Christine Pillai +4 more
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