Results 181 to 190 of about 10,791 (213)
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Mismatch base pairing of the mutagen 8‐oxoguanine and its derivatives with adenine: A theoretical search for possible antimutagenic agents

International Journal of Quantum Chemistry, 2004
AbstractMolecular geometries of 8‐oxoguanine (8OG), those of its substituted derivatives with the substitutions CH2, CF2, CO, CNH, O, and S in place of the N7H7 group, adenine (A), and the base pairs of 8OG and its substituted derivatives with adenine were optimized using the RHF/6‐31+G* and B3LYP/6‐31+G* methods in gas phase.
A. K. Singh, P. C. Mishra
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ChemInform Abstract: SIMPLE PRENYLATED HYDROQUINONE DERIVATIVES FROM THE MARINE UROCHORDATE APLIDIUM CALIFORNICUM. NATURAL ANTICANCER AND ANTIMUTAGENIC AGENTS

Chemischer Informationsdienst, 1980
AbstractIm Zusammenhang mit der Aufklärung von Naturstoffen wird die Reaktion von Hydrochinon (I) mit (II) zu den Substitutionsprodukten (III) und (IV) sowie deren weitere Cyclisierung bzw. Oxidation zu z.B. (V) oder (VI) untersucht.
B. M. HOWARD   +2 more
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[Antimutagens and anticarcinogenic agents, identification and mechanisms of action of food xenobiotics].

Therapie, 2003
Antimutagens and anticarcinogens are natural or synthetic substances able to inhibit or to reduce spontaneous or induced DNA alteration. These inhibitors act at different levels from the penetration of the xenobiotic to the expression of the mutation and cancer. They act in extracellular and intracellular levels; they react directly with mutagens or on
R, el Hamss, M, Idaomar
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Is man helpless against cancer? An environmental approach: antimutagenic agents from Egyptian food and medicinal preparations

Cancer Letters, 1994
Sixty-two Egyptian food and medicinal preparations were extensively examined for antimutagenic/anticarcinogenic activity using short-term and host-mediated assays. The antimutagenic activity of the substances examined was ranked as follows: thirteen (strong), seven (mild) and five (weak) after metabolic activation.
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Antimutagenic effects of 2(3)-tert-butyl-4-hydroxyanisole and of antimicrobial agents.

Cancer research, 1979
Administration of the antioxidants 2(3)-tert-butyl-4-hydroxyanisole (BHA) and ethoxyquin (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline) with the diet resulted in a marked decrease in the levels of mutagens present in mice treated with benzo(a)pyrene.
R P, Batzinger, S Y, Ou, E, Bueding
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Naturally Occurring Antimutagenic and Cytoprotective Agents

1999
Christine Pillai   +4 more
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[Studies of chemopreventive agents against neoplasma: synthesis of 3-acetyl coumarin derivatives and relationship between antimutagenic activity and structure].

Yao xue xue bao = Acta pharmaceutica Sinica, 1997
Twenty-five 3-acetylcoumarin derivatives were synthesized among which twenty-two were not reported before. Antimutagenic activity screen in vitro has shown that some of these compounds have various activities. The structure and activity relationship for 5-, 7-, 8-substituents has been studied.
X L, Huang, S P, Xu, Z D, Fu, B, An
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Can Lathyrus czeczottianus Bässler Be a New Source of Natural Antimutagenic Agents in Pharmacology? Evaluation from Mutagenic/Antimutagenic and Antimicrobial Perspectives

Bu çalışmada, Lathyrus czeczottianus bitkisinin toprak üstü kısımlarına ait metanol ve su özütlerinin mutajenite/antimutajenite ve antimikrobiyal özellikleri araştırılmıştır. Özütlerin toksik doz belirlemeleri yapıldıktan sonra, Ames testi (Salmonella/mikrozom) ile mutajenik özellikleri değerlendirilmiştir.
Kul, Mustafa, Uysal, Ahmet
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[Studies of antitumor and chemopreventive agents against neoplasm: synthesis of coumarin 3-glyoxal derivatives and relationship between structure and antimutagenic activity].

Yao xue xue bao = Acta pharmaceutica Sinica, 1998
It has been shown that alpha-glyoxal and its derivatives possess antivirus and antitumor activities. Eighteen new coumarin 3-glyoxal derivatives were synthesized in our laboratory. The fragmentation pattern of MS and the characteristic signals of 1HNMR of these compounds have also been studied.
X L, Huang   +4 more
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Screening for antimutagenic agents on environmental mutagens including nitro-and nitroso-compounds

Mutation Research/Environmental Mutagenesis and Related Subjects, 1978
T. Kada, M. Namiki
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