Results 11 to 20 of about 29,328 (300)

Coordinated regulation of the mitochondrial retrograde response by circadian clock regulators and ANAC017

Plant Communications, 2023
Mitochondrial retrograde signaling (MRS) supports photosynthetic function under a variety of conditions. Induction of mitochondrial dysfunction with myxothiazol (a specific inhibitor of the mitochondrial bc1 complex) or antimycin A (an inhibitor of the ...
Yanqiao Zhu, Reena Narsai, Cunman He, Yan Wang, Oliver Berkowitz, James Whelan, Lim Chee Liew   +6 more
doaj   +1 more source

Antimycin A-induced mitochondrial dysfunction regulates inflammasome signaling in human retinal pigment epithelial cells [PDF]

, 2021
Age-related macular degeneration (AMD) is a severe retinal eye disease where dysfunctional mitochondria and damaged mitochondrial DNA in retinal pigment epithelium (RPE) have been demonstrated to underlie the pathogenesis of this devastating disease.
Piippo, Niina, Hytti, Maria, Korhonen, Eveliina, Kaarniranta, Kai, Kauppinen, Anu   +4 more
core   +1 more source

Sarcopenia and aspartic acid magnesium

Journal of Physical Fitness and Sports Medicine, 2015
Sarcopenia from aging, inactivity, weightlessness, disease and malnutrition causes social problems due to associated physical dysfunction, a decrease in QOL, and risk of death.
Shigeru Yamada, Eriko Kizaki, Aya Ozeki, Mio Nakagawa, Hitomi Fujita   +4 more
doaj   +1 more source

Inhibition of Respiration of Candida albicans by Small Molecules Increases Phagocytosis Efficacy by Macrophages

mSphere, 2020
Candida albicans adapts to various conditions in different body niches by regulating gene expression, protein synthesis, and metabolic pathways. These adaptive reactions not only allow survival but also influence the interaction with host cells, which is
Shuna Cui, Minghui Li, Rabeay Y. A. Hassan, Anna Heintz-Buschart, Junsong Wang, Ursula Bilitewski   +5 more
doaj   +1 more source

Experimental Conditions That Influence the Utility of 2′7′-Dichlorodihydrofluorescein Diacetate (DCFH₂-DA) as a Fluorogenic Biosensor for Mitochondrial Redox Status

Antioxidants, 2022
Oxidative stress has been causally linked to various diseases. Electron transport chain (ETC) inhibitors such as rotenone and antimycin A are frequently used in model systems to study oxidative stress.
Lianne R. de Haan, Megan J. Reiniers, Laurens F. Reeskamp, Ali Belkouz, Lei Ao, Shuqun Cheng, Baoyue Ding, Rowan F. van Golen, Michal Heger   +8 more
doaj   +1 more source

Mitochondrial modulation-induced activation of vagal sensory neuronal subsets by antimycin A, but not CCCP or rotenone, correlates with mitochondrial superoxide production. [PDF]

PLoS ONE, 2018
Inflammation causes nociceptive sensory neuron activation, evoking debilitating symptoms and reflexes. Inflammatory signaling pathways are capable of modulating mitochondrial function, resulting in reactive oxygen species (ROS) production, mitochondrial ...
Katherine R Stanford, Thomas E Taylor-Clark   +1 more
doaj   +1 more source

Modified alternative oxidase expression results in different reactive oxygen species content in Arabidopsis cell culture but not in whole plants

Biologia Plantarum, 2012
Alternative oxidase (AOX) transfers electrons from ubiquinone to oxygen in the respiratory chain of plant mitochondria. It is widely accepted that AOX functions as a mechanism decreasing the formation of reactive oxygen species (ROS) produced during ...
V. I. Tarasenko, E. Y. Garnik, V. N. Shmakov, Y. M. Konstantinov   +3 more
doaj   +1 more source

Insecticidal characteristics and structural identification of the potential active compounds from Streptomyces sp. KR0006: Strain improvement through mutagenesis

PLoS ONE, 2022
Pest control by biological means is an effective, eco-friendly, and promising method that typically involves compounds naturally derived from actinomycetes. Thus, the present study aimed to screen, characterize, and identify the structure of insecticidal
Young Sook Kim, Mirjalol Umurzokov, Kwang Min Cho, Jung Sup Choi, Kee Woong Park   +4 more
doaj   +2 more sources

Influence of Antimycin A, a bacterial toxin, on human dermal fibroblast cell adhesion to tungsten-silicon oxide nanocomposites

Journal of Experimental Nanoscience, 2019
Nano- and micro-scale engineered surface structures are often used to control cell morphology and mimic the extracellular matrix in tissue engineering.
Hassan I. Moussa, Gyeongsu Kim, Jessica Tong, D. Moira Glerum, Ting Y. Tsui   +4 more
doaj   +1 more source

Rooibos Flavonoids, Aspalathin, Isoorientin, and Orientin Ameliorate Antimycin A-Induced Mitochondrial Dysfunction by Improving Mitochondrial Bioenergetics in Cultured Skeletal Muscle Cells

Molecules, 2021
The current study investigated the physiological effects of flavonoids found in daily consumed rooibos tea, aspalathin, isoorientin, and orientin on improving processes involved in mitochondrial function in C2C12 myotubes. To achieve this, C2C12 myotubes
Sinenhlanhla X. H. Mthembu, Christo J. F. Muller, Phiwayinkosi V. Dludla, Evelyn Madoroba, Abidemi P. Kappo, Sithandiwe E. Mazibuko-Mbeje   +5 more
doaj   +1 more source