Results 21 to 30 of about 29,328 (300)

Metabolomic Profiling and Genomic Study of a Marine Sponge-Associated Streptomyces sp.

Marine Drugs, 2014
Metabolomics and genomics are two complementary platforms for analyzing an organism as they provide information on the phenotype and genotype, respectively.
Christina Viegelmann, Lekha Menon Margassery, Jonathan Kennedy, Tong Zhang, Ciarán O'Brien, Fergal O'Gara, John P. Morrissey, Alan D. W. Dobson, RuAngelie Edrada-Ebel   +8 more
doaj   +1 more source

Oxylipins From Different Pathways Trigger Mitochondrial Stress Signaling Through Respiratory Complex III

Frontiers in Plant Science, 2021
Plant oxylipins are signaling molecules produced from fatty acids by oxidative pathways, mainly initiated by 9- and 13-lipoxygenases (9-LOX and 13-LOX), alpha-dioxygenases or non-enzymatic oxidation.
Yovanny Izquierdo, Luis Muñiz, Jorge Vicente, Jorge Vicente, Satish Kulasekaran, Verónica Aguilera, Ana López Sánchez, Ada Martínez-Ayala, Bran López, Tomás Cascón, Carmen Castresana   +10 more
doaj   +1 more source

Partially dissecting the steady-state electron fluxes in Photosystem I in wild-type and pgr5 and ndh mutants of Arabidopsis

Frontiers in Plant Science, 2015
Cyclic electron flux (CEF) around Photosystem I (PS I) is difficult to quantify. We obtained the linear electron flux (LEFO2) through both photosystems and the total electron flux through PS I (ETR1) in Arabidopsis in CO2-enriched air. DeltaFlux = ETR1
Jiancun eKou, Jiancun eKou, Shunichi eTakahashi, Da-Yong eFan, Da-Yong eFan, Murray R Badger, Wah Soon Chow   +6 more
doaj   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Aptly chosen, effectively emphasizing the action and mechanism of antimycin A1

Frontiers in Microbiology
Rhizoctonia solani Kühn, a plant pathogenic fungus that can cause diseases in multiple plant species is considered one of the common and destructive pathogens in many crops.
Linyan Zhu, Chenhong Weng, Xiaoman Shen, Xiangdong Zhu   +3 more
doaj   +1 more source

Bioactive Protopanaxatriol Type Saponins Isolated from the Roots of Panax Notoginseng (Burk.) F. H. Chen

Molecules, 2013
Seven new protopanaxatriol type saponins, 20S-sanchirhinosides A1 (1), A2 (2), A3 (3), A4 (4), A5 (5), and A6 (6), and sanchirhinoside B (7) were obtained as minor constituents from the root extract of Panax notoginseng (Burkill, F. H.
Tao Wang, Xiu-Mei Gao, Kojo Agyemang, Li-Li Liu, Kaunda Joseph Sakah, Zhi-Zhen Wu, Yi Zhang, Li-Feng Han   +7 more
doaj   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source

Regulation of antimycin biosynthesis by the orphan ECF RNA polymerase sigma factor σAntA [PDF]

PeerJ, 2014
Antimycins are an extended family of depsipeptides that are made by filamentous actinomycete bacteria and were first isolated more than 60 years ago.
Ryan F. Seipke, Elaine Patrick, Matthew I. Hutchings   +2 more
doaj   +2 more sources

A single Streptomyces symbiont makes multiple antifungals to support the fungus farming ant Acromyrmex octospinosus

, 2013
Attine ants are dependent on a cultivated fungus for food and use antibiotics produced by symbiotic Actinobacteria as weedkillers in their fungus gardens. Actinobacterial species belonging to the genera Pseudonocardia, Streptomyces and Amycolatopsis have
Brearley, Charles, Seipke, Ryan F., Barke, Joerg, Yu, Douglas W., Goss, Rebecca J. M., Hill, Lionel, Hutchings, Matthew I.   +6 more
core   +1 more source

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source