Results 1 to 10 of about 29,328 (300)
Biochimica Et Biophysica Acta - Bioenergetics, 1995 The structural factors of antimycin A molecule required for inhibitory action were studied using newly synthesized antimycin A derivatives with bovine heart submitochondrial particles, in order to probe the interaction between antimycin A and its binding site.
Hideto Miyoshi +2 more
exaly +4 more sources
Two Antimycin A Analogues from Marine-Derived Actinomycete Streptomyces lusitanus [PDF]
Marine Drugs, 2012 Two new antimycin A analogues, antimycin B1 and B2 (1–2), were isolated from a spent broth of a marine-derived bacterium, Streptomyces lusitanus. The structures of 1 and 2 were established on the basis of spectroscopic analyses and chemical methods.
Zhuang Han, Ying Xu, Lingli Liu
exaly +4 more sources
Coordinate Regulation of Antimycin and Candicidin Biosynthesis [PDF]
mSphere, 2016 Streptomyces species produce an incredible array of high-value specialty chemicals and medicinal therapeutics. A single species typically harbors ~30 biosynthetic pathways, but only a few them are expressed in the laboratory; thus, poor understanding of ...
Thomas C. McLean +2 more
doaj +8 more sources
Journal of Fungi, 2022 The application of chemical pesticides to protect agricultural crops from pests and diseases is discouraged due to their harmful effects on humans and the environment.
Sanjoy Kumar Paul +11 more
doaj +2 more sources
Context-specific Angiogenin-mediated tRNA fragments (tDRs) biogenesis shapes the mitochondrial stress response [PDF]
Redox BiologyTransfer RNA-derived small RNAs (tDRs) are emerging regulators of cellular stress response, yet their biogenesis and activities during mitochondrial dysfunction remain poorly understood.
Shadi Al-Mesitef +7 more
doaj +2 more sources
The regulation and biosynthesis of antimycins [PDF]
Beilstein Journal of Organic Chemistry, 2013 Antimycins (>40 members) were discovered nearly 65 years ago but the discovery of the gene cluster encoding antimycin biosynthesis in 2011 has facilitated rapid progress in understanding the unusual biosynthetic pathway.
Ryan F. Seipke, Matthew I. Hutchings
doaj +6 more sources
Exposure to Mitochondrial Toxins: An In Vitro Study of Energy Depletion and Oxidative Stress in Driving Dopaminergic Neuronal Death in MN9D Cells [PDF]
ToxicsMitochondrial dysfunction is a key contributor to neurodegeneration, particularly in Parkinson’s disease (PD), where dopaminergic neurons being highly metabolically active are vulnerable to oxidative stress and bioenergetic failure.
Oluwatosin Adefunke Adetuyi +1 more
doaj +2 more sources
Off-target effects of mitochondrial oxidative phosphorylation inhibitors are common and can compromise the viability of cultured cells [PDF]
Mitochondrial CommunicationsMitochondrial respiratory chain inhibitors (MRCIs) are indispensable for studying cellular bioenergetics and its effects on various cellular processes.
Natalya Kozhukhar, Mikhail F. Alexeyev
doaj +2 more sources
Assessing the effect of antimycin A on morphophysiological parameters in Triticum aestivum L. exposed to high temperature [PDF]
Journal of Central European Agriculture, 2021 The present study was conducted to investigate the evaluation of antimycin A (AA) as a modulator of the alternative respiratory pathway (AP) on the intensity of growth processes and some physiological parameters of etiolated wheat seedlings, such as ...
Anna Batjuka, Nataļja ŠKUTE
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 While irradiation with red LED light has been reported to modulate sperm function in different mammalian species, the mechanisms underlying their response are poorly understood.
Olga Blanco-Prieto +11 more
doaj +1 more source