Results 81 to 90 of about 25,615 (222)

Antimycobacterial Activities of Endolysins Derived From a Mycobacteriophage, BTCU-1

Molecules, 2015
The high incidence of Mycobacterium infection, notably multidrug-resistant M. tuberculosis infection, has become a significant public health concern worldwide.
Meng-Jiun Lai, Chih-Chin Liu, Shinn-Jong Jiang, Po-Chi Soo, Meng-Hsuan Tu, Jen-Jyh Lee, Ying-Huei Chen, Kai-Chih Chang   +7 more
doaj   +1 more source

Comparative Study of the Sensitivity of Different Diagnostic Methods for the Laboratory Diagnosis of Buruli Ulcer Disease [PDF]

, 2017
Background. Several diagnostic laboratory methods are available for case confirmation of Buruli ulcer disease. This study assessed the sensitivity of various diagnostic tests in relation to clinical presentation of the disease, type of diagnostic ...
Adjei, Ohene, Agbenorku, Pius, Awua-Boateng, Nana-Yaa, Beissner, Marcus, Bretzel, Gisela, Fleischer, Bernhard, Fleischmann, Erna, Helfrich, Kerstin, Herbinger, Karl-Heinz, Klutse, Erasmus, Kunaa, Letitia, Lüscher, Thomas, Nienhuis, Willemien A., Nitschke, Jürg, Racz, Paul, Reu, Simone, Schipf, Alexander, Siegmund, Vera, Thompson, William, van der Werf, Tjip S.   +19 more
core  

Hemophagocytic Lymphohistiocytosis Secondary to Disseminated Bacillus Calmette–Guérin (BCG): A Steroid‐Sparing Strategy in a Patient Awaiting Cardiac Surgery—A Case Report

Case Reports in Hematology, Volume 2026, Issue 1, 2026.
We report a case of hemophagocytic lymphohistiocytosis (HLH) secondary to disseminated Bacillus Calmette–Guérin (BCG) infection in an 80‐year‐old man treated with intravesical BCG for non–muscle‐invasive bladder cancer. The patient presented with several weeks of constitutional symptoms including night sweats, fatigue, weight loss, confusion, and ...
Kaitlin Quinlan, Tyler MacDonald, Terence C. Wuerz, Ryan Zarychanski, Yoshito Nishimura   +4 more
wiley   +1 more source

Traffic-Related Air Pollution and All-Cause Mortality during Tuberculosis Treatment in California. [PDF]

, 2017
BackgroundAmbient air pollution and tuberculosis (TB) have an impact on public health worldwide, yet associations between the two remain uncertain.ObjectiveWe determined the impact of residential traffic on mortality during treatment of active TB ...
Brenda Jones, CDC (Centers for Disease Control and Prevention)., Dan Meltzer, Donald G. Catanzaro, Fielder JF, Jennifer Flood, John Balmes, Lisa Pascopella, Mark R. Segal, Paul B. English, Payam Nahid, Pennan M. Barry, Robert J. Blount, Slama K, Sterling TR, Webb GB   +15 more
core   +1 more source

Licochalcone A as Novel Multitarget Inhibitors via AChE, BuChE, and Synapsin III for Therapeutic Intervention Against Alzheimer’s Disease: Computer‐Aided Drug Design

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Alzheimer’s disease (AD) is characterized by key pathological features, including cholinergic dysfunction, amyloid‐beta (Aβ) aggregation, and disrupted synaptic transmission, positioning proteins such as acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and Synapsin III as critical targets for therapeutic strategies.
Ali Alimari, Bagher Seyedalipour, Payam Baziyar, Ehsan Joz Jalalian, Sohini Basu Roy   +4 more
wiley   +1 more source

Antimicrobial treatment improves mycobacterial survival in nonpermissive growth conditions [PDF]

, 2014
Antimicrobials targeting cell wall biosynthesis are generally considered inactive against nonreplicating bacteria. Paradoxically, we found that under nonpermissive growth conditions, exposure of Mycobacterium bovis BCG bacilli to such antimicrobials ...
Andrew, Peter W, Burke, Bernard, Butcher, Philip D, Cohen-Gonsaud, Martin, Glenn, Sarah, Labesse, Gilles, Mukamolova, Galina V, Sarybaeva, Asel A, Tudo, Griselda, Turapov, Obolbek, Waddell, Simon J, Young, Danielle I, Young, Michael   +12 more
core   +2 more sources

ANTIMYCOBACTERIAL COMPOUNDS FROM NASTURTIUM OFFICINALE

African Journal of Traditional, Complementary and Alternative Medicines, 2016
Background: Nasturtium officinale is a plant used in Mexican traditional medicine to treat respiratory infections such as tuberculosis. In previous studies, it was found that the chloroform extract of the aerial parts of N. officinale showed good activity against one sensitive and four drug-resistant Mycobacterium tuberculosis H37Rv strains.
Quezada-Lázaro, Rodrígo, Fernández-Zuñiga, Eunice A., García, Abraham, Garza-González, Elvira, Alvarez, Laura, Camacho-Corona, María del Rayo   +5 more
openaire   +2 more sources

The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira, Robson Xavier Faria, Wei Wang   +2 more
wiley   +1 more source

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

ChemPlusChem, Volume 90, Issue 12, December 10, 2025.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

Mulinane- and Azorellane-Type Diterpenoids: A Systematic Review of Their Biosynthesis, Chemistry, and Pharmacology

Biomolecules, 2020
Mulinane- and azorellane-type diterpenoids have unique tricyclic fused five-, six-, and seven-membered systems and a wide range of biological properties, including antimicrobial, antiprotozoal, spermicidal, gastroprotective, and anti-inflammatory, among ...
Angel de Jesús Dzul-Beh, Andrés Humberto Uc-Cachón, Jorge Bórquez, Luis A. Loyola, Luis Manuel Peña-Rodríguez, Gloria María Molina-Salinas   +5 more
doaj   +1 more source