Results 111 to 120 of about 11,373 (215)

Antimycobacterial activity of econazole against multidrug-resistant strains of Mycobacterium tuberculosis [PDF]

, 2006
This study evaluated the antimycobacterial activity of econazole against multidrug-resistant (MDR) strains of Mycobacterium tuberculosis. The minimum inhibitory concentration (MIC90) and minimum bactericidal concentration (MBC>99.99) against MDR ...
Sharma, Sadhna, Katoch, V. M., Ahmad, Zahoor, Faujdar, Jaya, Khuller, G. K., Singh, Pushpendra   +5 more
core   +1 more source

In Silico Structure-Activity Study of Selected Triterpenoids as Potential Inhibitors of Mycolic Acid Transporter of Mycobacterial MmpL3 Receptor Protein

Sciences of Phytochemistry
Structural features of the triterpenoid skeleton that are necessary for antimycobacterial activity are not well understood. Following the isolation of the triterpenoids ergosterol-5,8-endoperoxide, 6β-hydroxykulactone, 12β-hydroxykulactone, (24R)-24,25 ...
Mohamed Said Rajab
doaj   +1 more source

Novel Thiazolidinone-Azole Hybrids: Design, Synthesis And Antimycobacterial Activity Studies [PDF]

, 2016
To develop novel antimycobacterial agents, a new series of thiazolidinone-azole hybrids 4a-b, 5a-b and 6-13 were designed and synthesized. Thiazolidin-4-ones (4a-b and 5a-b) were obtained by the reaction of Schiff bases and hydrazones (2a-b and 3a-b ...
Oya Unsal-Tan, Ozadali-Sari, Keriman, Unsal-Tan, Oya, Eroglu, Barbaros, Ayla Balkan, Keriman Ozadali-Sari, Yogeeswari, Perumal, Balkan, Ayla, Barbaros Eroglu, Sriram Dharmarajan, Dharmarajan, Sriram, Perumal Yogeeswari   +11 more
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Fractions and isolated compounds from Oxyanthus speciosus subsp. stenocarpus (Rubiaceae) have promising antimycobacterial and intracellular activity

BMC Complementary and Alternative Medicine, 2019
Background Tuberculosis is a deadly disease caused by Mycobacterium species. The use of medicinal plants is an ancient global practice for the treatment and prevention of diverse ailments including tuberculosis.
Abimbola O. Aro, Jean P. Dzoyem, Maurice D. Awouafack, Mamoalosi A. Selepe, Jacobus N. Eloff, Lyndy J. McGaw   +5 more
doaj   +1 more source

Phytochemical analysis and evaluation of antioxidant and antimycobacterial activity of Colletia paradoxa from Brazil [PDF]

, 2019
Colletia paradoxa (Spreng.) Esc. (Rhamnaceae, Colletieae) is a medicinal plant, threatened with extinction in Brazil, presenting great morphological variability.
Fallon dos Santos Siqueira (16889662), Nelci Rolim Bastos Záchia (6592256), Margareth Linde Athayde (6592265), Mariana Piana (6592259), Marli Matiko Anraku de Campos (5952800), Liliana Essi (6592268), Roberta da Silva Jesus (6592262)   +6 more
core   +1 more source

Antimycobacterial activity of Byrsonima crassa Nied leaf extracts [PDF]

, 2008
In this study, the antimycobacterial activity of chloroformic and methanolic extracts obtained from Byrsonima crassa leaves was evaluated. Antimycobacterial activity was assessed through the microtechnique named Microplate Alamar Blue Assay (MABA) and ...
Leite, C. Q F [UNESP], Sato, D. N., Sannomiya, M. [UNESP], Pavan, F. R. [UNESP], Higuchi, C. T. [UNESP], Vilegas, Wagner [UNESP]   +5 more
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Antimycobacterial activity of lichen metabolites in vitro

European Journal of Pharmaceutical Sciences, 1998
Several compounds, whose structures represent the most common chemical classes of lichen metabolites, were screened for in vitro activity against Mycobacterium aurum, a non-pathogenic organism with a similar sensitivity profile to M. tuberculosis. Of the compounds tested, usnic acid from Cladonia arbuscula exhibited the highest activity with an MIC ...
K, Ingólfsdóttir, G A, Chung, V G, Skúlason, S R, Gissurarson, M, Vilhelmsdóttir   +4 more
openaire   +2 more sources

Organ-Specific Distribution of Antimycobacterial Neolignans in Piper rivinoides and UHPLC-HRMS/MS Analysis of Its Extracts

Molecules
This multidisciplinary study investigates Piper rivinoides, a Brazilian medicinal species, focusing on its chemical composition and antimycobacterial potential.
Jéssica Sales Felisberto, Thayssa Ferreira Fagundes, Lorraynne Oliveira-Souza, Bruno Henrique Gomes de Souza, Daniel Machado de Brito, Jeferson Adriano Assunção, Samik Lourenço Massau, Marlon H. de Araújo, Michelle Frazão Muzitano, Sanderson Dias Calixto, Thatiana Lopes Biá Ventura Simão, Andre Mesquita Marques, Ygor Jessé Ramos, Davyson de Lima Moreira   +13 more
doaj   +1 more source

Antimycobacterial activity of novel hydrazide-hydrazone derivatives with 2H-chromene and coumarin scaffold [PDF]

, 2017
This study reports the synthesis of new 2H-chromene or coumarin based acylhydrazones, which were evaluated for their in vitro antimycobacterial activity against reference strain Mycobacterium tuberculosis H37Rv and compared to the first-line ...
Momekov, G., Dimitrov, I., Dimitrov, Ivan, Buyukliev, Rosen, Angelova, Violina T., Momekov, Georgi, Valcheva, V., Shivachev, Boris, Angelova, V. T., Saso, L., Buyukliev, R., Shivachev, B., Valcheva, Violeta, Saso, Luciano, Djukic, M., Vassilev, N. G., Đukić, Mirjana, Vassilev, Nikolay G.   +17 more
core   +1 more source

Synthesis, structure-activity relationship and solubility profiling of antimycobacterial aminoquinazolinones [PDF]

, 2017
Tuberculosis (TB) is a communicable disease caused by an infectious bacterial pathogen called Mycobacterium tuberculosis (Mtb), which is acquired through the inhalation of bacilli-containing droplets.
Akester, Jessica Nicole
core   +1 more source