Results 171 to 180 of about 11,373 (215)

Exploring Scaffold Hopping for Novel 2-(Quinolin-4-yloxy)acetamides with Enhanced Antimycobacterial Activity. [PDF]

ACS Med Chem Lett
Borsoi AF, Silva Ramos A, Sperotto N, Abbadi BL, Souza Macchi Hopf F, da Silva Dadda A, Scheibler Rambo R, Neves Muniz M, Delgado Paz J, Silveira Grams E, Fries da Silva F, Pissinate K, Galina L, Calle González L, Silva Duarte L, Alberton Perelló M, de Matos Czeczot A, Bizarro CV, Basso LA, Machado P.   +19 more
europepmc   +1 more source

Potentiation of the antimycobacterial activity of bedaquiline, clofazimine, and doxycycline against <i>Mycobacterium smegmatis</i> by several natural product-based compounds is putatively via efflux inhibition. [PDF]

Open Res Afr
Chacha R, Maina C, Murungi E, Guantai E, Ngugi MP, Ndirangu E, Mugo J, Njeru SN, Kigondu E.   +8 more
europepmc   +1 more source

Synthesis, Structure-Activity Relationship, and Mechanistic Studies of Aminoquinazolinones Displaying Antimycobacterial Activity. [PDF]

ACS Infect Dis, 2020
Akester JN, Njaria P, Nchinda A, Le Manach C, Myrick A, Singh V, Lawrence N, Njoroge M, Taylor D, Moosa A, Smith AJ, Brooks EJ, Lenaerts AJ, Robertson GT, Ioerger TR, Mueller R, Chibale K, Chibale K.   +17 more
europepmc   +1 more source

Bis-(imidazole/benzimidazole)-pyridine derivatives: synthesis, structure and antimycobacterial activity. [PDF]

Future Med Chem, 2020
Antoci V, Cucu D, Zbancioc G, Moldoveanu C, Mangalagiu V, Amariucai-Mantu D, Aricu A, Mangalagiu II.   +7 more
europepmc   +1 more source

Design, synthesis and antimycobacterial activity of imidazo[1,5-a]quinolines and their zinc-complexes. [PDF]

RSC Med Chem
Marner M, Kulhanek N, Eichberg J, Hardes K, Molin MD, Rybniker J, Kirchner M, Schäberle TF, Göttlich R.   +8 more
europepmc   +1 more source

Phytochemistry and antimycobacterial activity of Chlorophytum inornatum [PDF]

Phytochemistry, 2006
In a project to investigate plant derived natural products from the Liliaceae with activity against fast-growing strains of mycobacteria, we have identified two new metabolites from Chlorophytum inornatum. The active principle, a new homoisoflavanone (1) was identified as 3-(4'-methoxybenzyl)-7,8-methylenedioxy-chroman-4-one. The metabolite assigned as
O’Donnell, Gemma, Bucar, Franz, Gibbons, Simon   +2 more
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Synthesis and antimycobacterial activity of calpinactam derivatives

Bioorganic and Medicinal Chemistry Letters, 2012
Synthesis of calpinactam 1, a fungal antimycobacterial metabolite, utilizing solid-phase peptide synthesis is described. To explore the structure-activity relationships of 1, its derivatives with different amino acids were also synthesized on the basis of the same synthetic strategy.
Kenichiro Nagai, Nobuhiro Koyama, Hiroshi Tomoda   +2 more
exaly   +3 more sources

Antimycobacterial activity of ‘Virkon’

Journal of Hospital Infection, 1993
The peroxygen-based disinfectant, 'Virkon' (at concentrations of 2, 3 and 4%) was tested against Mycobacterium tuberculosis and M. avium-intracellulare over exposure times ranging between 30 and 120 min. Two test procedures were used: (a) a standard plate method, (b) a method incorporating the use of the 'Bactec' 460 radiometric system to chart ...
S J, Broadley, J R, Furr, P A, Jenkins, A D, Russell   +3 more
openaire   +2 more sources

Activation of macrophages for antimycobacterial activity

Immunology Letters, 1985
The role of macrophage hydrogen peroxide in defense against mycobacterial infection is discussed - not because this is necessarily any more important than other macrophage products (reviews: [1, 2]) but more as a reflection of recently available information.
D B, Lowrie, P S, Jackett, P W, Andrew
openaire   +2 more sources