Results 181 to 190 of about 19,828 (226)

Antimycobacterial Activity of Some Turkish Plants

Pharmaceutical Biology, 2004
In this study, 70% ethanol extracts from 98 different plant species distributed among 21 families were evaluated for antimycobacterial activity. Sempervirine was isolated from Buxus sempervirens with a minimum inhibitory concentration (MIC) of 6.25 µg/ml.
Bilge Sener, Prasit Palittapongarnpim
exaly   +3 more sources

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Antimycobacterial activity of ‘Virkon’

Journal of Hospital Infection, 1993
The peroxygen-based disinfectant, 'Virkon' (at concentrations of 2, 3 and 4%) was tested against Mycobacterium tuberculosis and M. avium-intracellulare over exposure times ranging between 30 and 120 min. Two test procedures were used: (a) a standard plate method, (b) a method incorporating the use of the 'Bactec' 460 radiometric system to chart ...
S J, Broadley, J R, Furr, P A, Jenkins, A D, Russell   +3 more
openaire   +2 more sources

New Agents with Antimycobacterial Activity

Archiv der Pharmazie, 2005
AbstractIn this paper, we report that a series of structurally simple a‐halogenoacetamides (1–8) show potent and excellent antimycobacterial activities against drug‐sensitive Mycobacterium tuberculosis H37Rv and drug‐resistant M. avium.
José, Marco-Contelles, Elena, Gómez-Sánchez   +1 more
openaire   +2 more sources

Activation of macrophages for antimycobacterial activity

Immunology Letters, 1985
The role of macrophage hydrogen peroxide in defense against mycobacterial infection is discussed - not because this is necessarily any more important than other macrophage products (reviews: [1, 2]) but more as a reflection of recently available information.
D B, Lowrie, P S, Jackett, P W, Andrew
openaire   +2 more sources

Substituted Xanthones as Antimycobacterial Agents, Part 2: Antimycobacterial Activity

Archiv der Pharmazie, 1998
A series of substituted xanthones was tested for their activity against four mycobacterial strains (Mycobacterium tuberculosis, M. avium, M. lufu, M. smegmatis) by determination of the minimum inhibitory concentrations (MIC values). For the most active compounds, supplementary characterisation was performed by bacterial growth kinetics, which allows a ...
Pickert, Martina, Schaper, Klaus Jürgen, Frahm, August Wilhelm   +2 more
openaire   +2 more sources

Antimycobacterial activity of diphenylpyraline derivatives

European Journal of Medicinal Chemistry, 2008
2-Substituted derivatives of diphenylpyraline and their 1-phenyl and 1-phenethyl analogues have been prepared in several steps from dihydropyridine-2(1H)-thiones. The structures of all new compounds have been confirmed by NMR spectroscopy. Their activity against Mycobacterium tuberculosis H(37)Rv as well as their cytotoxicity against human cells (HEK ...
Robert, Weis, Johanna, Faist, Ulrike, di Vora, Klaus, Schweiger, Barbara, Brandner, Andreas J, Kungl, Werner, Seebacher   +6 more
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Antimycobacterial activity of ionic fullerene derivatives

Bioorganic & Medicinal Chemistry Letters, 2000
Positively charged fullerene derivatives, moderately soluble in water:DMSO 9:1, have been tested using three strains of Mycobacterium spp. Some compounds inhibit the growth of Mycobacterium tuberculosis, a human clinical isolate, particularly virulent and resistant, at doses as low as 5 microg/mL.
BOSI, Susanna, DA ROS, TATIANA, S. CASTELLANO, BANFI, ELENA, PRATO, MAURIZIO   +4 more
openaire   +4 more sources

Antimycobacterial Activity of 1‐Substituted Indolizines

Archiv der Pharmazie, 2003
AbstractIndolizine derivatives were tested as antimycobacterials against Mycobacterium tuberculosis H37Rv (ATCC 27294)in BACTEC 12B medium using the Microplate Alamar Blue Assay. The most active compounds examined carry an α‐hydroxybenzyl substituent in the indolizine 1‐position.
Lise-Lotte, Gundersen, Ayele H, Negussie, Frode, Rise, Ole Benny, ØStby   +3 more
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Rapid measurement of antimycobacterial drug activity

Research in Microbiology, 1996
68024
Gordon, S, Houldsworth, S, Roberts, IS, Andrew, PW, Duncan, K   +4 more
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Antimycobacterial Activities of Oxazolidinones: A Review

Infectious Disorders - Drug Targets, 2006
Oxazolidinones are a new class of totally synthetic antibacterial agents with wide spectrum of activity against a variety of clinically significant susceptible and resistant bacteria. These compounds have been shown to inhibit translation at the initiation phase of protein synthesis.
R, Sood, T, Bhadauriya, M, Rao, R, Gautam, S, Malhotra, T K, Barman, D J, Upadhyay, A, Rattan   +7 more
openaire   +2 more sources