Effect of dexmedetomidine on Nociception Level Index-guided remifentanil antinociception
The effect of dexmedetomidine on Nociception Level Index (Medasense, Israel) antinociception to reduce intra-operative opioid requirements has not been previously investigated.SCOPUS: ar.jinfo:eu-repo/semantics ...
Kapessidou, Panayota +21 more
core +1 more source
Mechanisms of the Antinociceptive Action of Gabapentin
Gabapentin, a gamma-aminobutyric acid (GABA) analogue anticonvulsant, is also an effective analgesic agent in neuropathic and inflammatory, but not acute, pain systemically and intrathecally. Other clinical indications such as anxiety, bipolar disorder, and hot flashes have also been proposed. Since gabapentin was developed, several hypotheses had been
Cheng, Jen-Kun, Chiou, Lih-Chu
openaire +4 more sources
Characterization of cholinergic-induced antinociception in the ventral medial medulla in rats.
Characterization of cholinergic-induced antinociception in the ventral medial medulla in ...
Margie Anne. McCartney (7959059)
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An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons
We have developed a highly effective method for in vivo gene silencing in the spinal cord and dorsal root ganglia (DRG) by a cationic lipid facilitated delivery of synthetic, small interfering RNA (siRNA). A siRNA to the delta opioid receptor (DOR), or a
Porreca Frank +6 more
doaj +1 more source
Pharmacological studies of anti-inflammatory, anti-nociceptive and anti-pyretic compounds found in chromatographic fractions of Anogeissus leiocarpa (DC). Guill. & Perr. leaves [PDF]
Context: The anti-nociceptive and anti-pyretic properties of the crude aqueous extract of Anogeissus leiocarpa (DC). Guill. & Perr. leaves have been reported. Aims: To investigate the anti-inflammatory, anti-nociceptive, and anti-pyretic properties of
Precious A. Idakwoji +9 more
doaj
Dose-Dependent Effect of GABAA System on Antinociception Actions of Cuneiformis Nucleus in Brain Stem [PDF]
Background and Objective: It's been established that midbrain region namely rostral ventromedial medulla (RVM) is the coring point of modulation of pain.
شیخکانلوی میلان, حمید
core
AMPK contributes to aerobic exercise-induced antinociception downstream of endocannabinoids
S.134-142Physical exercise has been repeatedly associated with decreased nociceptive responses but the underlying mechanisms have still not been fully clarified.
Möser, C.V. +8 more
core +1 more source
Antinociceptive effect of intrathecal neostigmine evaluated in rats by two different pain models
The analgesic efficacy of cholinergic agonists and anticholinesterase agents has been widely recognized. The analgesic effect obtained by activating cholinergic mechanisms, however, seems to depend on the experimental pain model utilized for its ...
Prado W.A., Gonçalves A.S.
doaj
TRPA1 Channel is Involved in SLIGRL-Evoked Thermal and Mechanical Hyperalgesia in Mice
Persistent itch (pruritus) accompanying dermatologic and systemic diseases can significantly impair the quality of life. It is well known that itch is broadly categorized as histaminergic (sensitive to antihistamine medications) or non-histaminergic ...
Merab G. Tsagareli +3 more
doaj +1 more source
Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (m, d, k) in the antinociception-modulating ...
DiPirro, Jean M., Kristal, Dr. Mark B.
core

