Results 81 to 90 of about 93,093 (250)

Bacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage

open access: yesAdvanced Science, EarlyView.
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Jianmu Su   +10 more
wiley   +1 more source

An overview of anti-diabetic plants used in Gabon: Pharmacology and Toxicology [PDF]

open access: yes, 2018
© 2017 Elsevier B.V. All rights reserved.Ethnopharmacological relevance: The management of diabetes mellitus management in African communities, especially in Gabon, is not well established as more than 60% of population rely on traditional treatments as ...
A. Souza   +374 more
core   +4 more sources

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

Effects of industrial heat treatments on the kinetics of inactivation of antimicrobial bovine milk xanthine oxidase. [PDF]

open access: yes, 2019
Milk is a source of antimicrobial systems such as xanthine oxidoreductase, which has been proposed to modulate the oral and gut microbiota of infants.
de Moura Bell, Juliana MLN   +2 more
core  

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

open access: yesAdvanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet   +5 more
wiley   +1 more source

Hydroxypropyl-β-cyclodextrin as an effective carrier of curcumin – piperine nutraceutical system with improved enzyme inhibition properties

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
The nutraceutical system of curcumin-piperine in 2-hydroxypropyl-β-cyclodextrin was prepared by using the kneading technique. Interactions between the components of the system were defined by X-ray powder diffraction (XRPD), differential scanning ...
Anna Stasiłowicz   +9 more
doaj   +1 more source

Bioactivity of phenolic acids: Metabolites versus parent compounds: A review [PDF]

open access: yes, 2015
Phenolic acids are present in our diet in different foods. In particular, mushrooms are a good source of these molecules. Due to their bioactive properties, phenolic acids are extensively studied and there is evidence of their role in disease ...
Ferreira, Isabel C. F. R.   +3 more
core   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

open access: yesAdvanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu   +11 more
wiley   +1 more source

Evaluation of the Antimicrobial, Antioxidant, Anticholinesterase, and Antidiabetic Activities of Matricaria chamomilla, Lavandula angustifolia, Hypericum perforatum, Salvia officinalis, and Foeniculum vulgare Extracts

open access: yesTurkish Journal of Agriculture: Food Science and Technology
This study evaluated and compared the antimicrobial, antioxidant, anticholinesterase, and antidiabetic activities of Matricaria chamomilla L. (chamomile), Lavandula angustifolia Mill. (lavender), Hypericum perforatum L. (St.
Meryem Uğurlu   +5 more
doaj   +1 more source

Pharmacological activities of leaf and bark extracts of a medicinal mangrove plant Avicennia officinalis L.

open access: yesClinical Phytoscience, 2018
Background Avicennia officinalis is a medicinally important mangrove plant and used in traditional medicinal practices to treat various ailments like rheumatism, paralysis, asthma, dyspepsia, tumors etc. The objective of the present study was to evaluate
Swagat Kumar Das   +5 more
doaj   +1 more source

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