Results 41 to 50 of about 492,470 (313)

Differential redox state contributes to sex disparities in the response to influenza virus infection in male and female mice [PDF]

, 2018
Influenza virus replicates intracellularly exploiting several pathways involved in the regulation of host responses. The outcome and the severity of the infection are thus strongly conditioned by multiple host factors, including age, sex, metabolic ...
Ann Maria Clemente, Anna Rita Vestri, Anna Teresa Palamara, Anna Teresa Palamara, Caterina Loredana Mammola, Danilo Alunni Fegatelli, Donatella Amatore, Enrico Garaci, Ignacio Celestino, Lucia Nencioni, Maria Gabriella Torcia, Marta De Angelis, Paola Checconi, Paola Matarrese, Paolo Coluccio, Romina Mancinelli, Rosanna Dattilo, Walter Malorni   +17 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Adaptive response to oxidative stress in the filamentous fungus Aspergillus niger B1-D [PDF]

, 2008
In the present study, we used a recombinant filamentous fungus strain, Aspergillus niger B1-D, as a model system, and investigated the antioxidant defences in this organism.
Harvey, L.M., Li, Qiang, Mcneil, Brian
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Genetic Basis of the Antioxidant and Serum Enzyme Activities of the Large Yellow Croaker Larimichthys crocea Under Stress in an Experimental Simulation of Natural Winter Water Cooling

Antioxidants
Antioxidant and serum enzyme activities of the large yellow croaker (Larimichthys crocea) were analyzed to investigate the influences of genotype and water temperature.
Xinan Wang, Xiaolong Yin, Aijun Ma, Weiye Li, Xiaolin Zhang   +4 more
doaj   +1 more source

Paraquat pretreatment alters antioxidant enzyme activity and protects chloroplast ultrastructure in heat-stressed cucumber leaves

Biologia Plantarum, 2011
Cucumis sativus L. seedlings were pretreated 1 h with 10 μM paraquat (PQ) and then were subjected to normal (25/18 °C) or elevated (42/38 °C) temperature to investigate whether PQ can protect plants against heat stress.
Y. Gao, Y. -K. Guo, A. -H. Dai, W. -J. Sun, J. -G. Bai   +4 more
doaj   +1 more source

Antioxidant and antihypertensive activities of rice bran peptides [PDF]

, 2011
Protein isolates and peptide fractions from food sources (cereal grains), have been shown to exert bioactive properties including antiobesity, anticancer, antiangiogenic, etc.
Hettiarachchy, Navam S., Hull, Janika, Kannan, Arvind   +2 more
core   +2 more sources

Influence of preparation procedures on the phenolic content, antioxidant and antidiabetic activities of green and black teas [PDF]

, 2019
The influence of common tea preparation procedures (temperature, infusion time, consumption time interval and tea bag/loose-leaf) and the type of water used, on the total phenolic content (TPC), the radical scavenging activity and the alpha-glucosidase ...
Almeida, Tânia Santos de, Araújo, Maria Eduarda Machado, Borges dos Santos, R. M., Júlio, Ana, Mendes, Beatriz Garcia, Rodríguez, Lucía González, Simões, José Artur Martinho   +6 more
core   +3 more sources

Trace elements as an activator of antioxidant enzymes

Postępy Higieny i Medycyny Doświadczalnej, 2016
Oxidative stress is a state of impaired balance between the formation of free radicals and antioxidant capacity of the body. It causes many defects of the body, e.g. lipid peroxidation, DNA and protein damage. In order to prevent the effects of oxidative stress, the organism has developed defence mechanisms.
Marta, Wołonciej, Elżbieta, Milewska, Wiesława, Roszkowska-Jakimiec   +2 more
openaire   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source