Results 51 to 60 of about 1,849,004 (361)

Differential redox state contributes to sex disparities in the response to influenza virus infection in male and female mice [PDF]

open access: yes, 2018
Influenza virus replicates intracellularly exploiting several pathways involved in the regulation of host responses. The outcome and the severity of the infection are thus strongly conditioned by multiple host factors, including age, sex, metabolic ...
Ann Maria Clemente   +17 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Antioxidant and antihypertensive activities of rice bran peptides [PDF]

open access: yes, 2011
Protein isolates and peptide fractions from food sources (cereal grains), have been shown to exert bioactive properties including antiobesity, anticancer, antiangiogenic, etc.
Hettiarachchy, Navam S.   +2 more
core   +2 more sources

Elucidating the genetic basis of antioxidant status in lettuce (Lactuca sativa). [PDF]

open access: yes, 2015
A diet rich in phytonutrients from fruit and vegetables has been acknowledged to afford protection against a range of human diseases, but many of the most popular vegetables are low in phytonutrients. Wild relatives of crops may contain allelic variation
Biggi, Gaia F   +10 more
core   +1 more source

Effects of Heat Shock on Photosynthetic Properties, Antioxidant Enzyme Activity, and Downy Mildew of Cucumber (Cucumis sativus L.)

open access: yesPLoS ONE, 2016
Heat shock is considered an abiotic stress for plant growth, but the effects of heat shock on physiological responses of cucumber plant leaves with and without downy mildew disease are still not clear.
Xiaotao Ding   +9 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Genetic Basis of the Antioxidant and Serum Enzyme Activities of the Large Yellow Croaker Larimichthys crocea Under Stress in an Experimental Simulation of Natural Winter Water Cooling

open access: yesAntioxidants
Antioxidant and serum enzyme activities of the large yellow croaker (Larimichthys crocea) were analyzed to investigate the influences of genotype and water temperature.
Xinan Wang   +4 more
doaj   +1 more source

Efecto del estrés producido por la mezcla de sales en la concentración de aldehído malónico, proteínas y enzimas antioxidantes de Leymus chinensis de tres colores foliares diferentes [PDF]

open access: yes, 2017
The mixed salt stress is common in nature. Salt stressalways affects plant growth. Different plant species have different adaptive capacity to salty soil. Leymus chinensis is an herbaceous plant with different leaf colors.
Busso, Carlos Alberto   +6 more
core  

Trace elements as an activator of antioxidant enzymes

open access: yesPostępy Higieny i Medycyny Doświadczalnej, 2016
Oxidative stress is a state of impaired balance between the formation of free radicals and antioxidant capacity of the body. It causes many defects of the body, e.g. lipid peroxidation, DNA and protein damage. In order to prevent the effects of oxidative stress, the organism has developed defence mechanisms.
Marta, Wołonciej   +2 more
openaire   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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