Results 111 to 120 of about 300,461 (163)

Antioxidant Enzymes and Apoptosis

Drug Metabolism Reviews, 2004
The role of antioxidant enzymes can be interpreted in terms of fine tuning of the concentration of reactive oxygen species which are required in the redox regulation of the cell cycle and of programmed cell death. This review summarizes findings from papers published in the last few years which deal with the relation between apoptosis and the two ...
Regine, Kahl, Andreas, Kampkötter, Wim, Wätjen, Yvonni, Chovolou   +3 more
openaire   +2 more sources

Antioxidant Enzymes and Diabetic Retinopathy

Annals of the New York Academy of Sciences, 2007
Abstract:  The aim of this study was to discuss the serum copper (Cu), zinc (Zn), nitric oxide (NO), glutathione (GSH), advanced oxidation protein products (AOPP) levels, and superoxide dismutase (SOD) activities with diabetic retinopathy severity.
Guersel, E., Yildirim, Zuhal, Ucgun, N. Irem, Kilic, Nedret, Sepici-Dincel, AYLİN   +4 more
openaire   +3 more sources

Microbial antioxidant defense enzymes

Microbial Pathogenesis, 2017
Free radicals are often described as chemical compounds characterized by unpaired electrons in their outer orbital rendering them highly reactive species. In mammalians, studies on free radicals were focused on reactive oxygen species (ROS) or reactive nitrogen species (RNS) due to their relative importance in physiological as well as in pathological ...
Staerck, Cindy, Gastebois, Amandine, Vandeputte, Patrick, Calenda, Alphonse, Larcher, Gérald, Gillmann, Louiza, Papon, Nicolas, Bouchara, Jean-Philippe, Fleury, Maxime J.J.   +8 more
openaire   +2 more sources

Antioxidant enzymes and human diseases

Clinical Biochemistry, 1999
To describe the importance of the antioxidant enzymes superoxide dismutase, glutathione peroxidase, and catalase working together in human cells against toxic reactive oxygen species, their relationship with several pathophysiologic processes and their possible therapeutic implications.Reactive oxygen species (ROS) are involved in the cell growth ...
J M, Matés, C, Pérez-Gómez, I, Núñez de Castro   +2 more
openaire   +2 more sources

Regulation of Antioxidant Enzymes

The Journal of Nutrition, 1992
Free radicals generated by a partial reduction of O2 pose a serious hazard to tissues and vital organs, especially membrane lipids, connective tissues, and the nucleic acids of cells. For protection, enzymes have evolved that specifically attack O2-, hydrogen, and organic peroxides, and repair any damage incurred to DNA.
openaire   +3 more sources

Antioxidant Enzyme Mimics with Synergism

Mini-Reviews in Medicinal Chemistry, 2010
The antioxidant enzymes, such as superoxide dismutase, catalase, glutathione peroxidase, and glutathione S-transferase contribute dominatingly to enhance cellular antioxidant defense against oxidative stress. They act cooperatively to scavenge reactive oxygen species, and not one of them can singlehandedly clear all forms of reactive oxygen species. On
Fei, Yan, Ying, Mu, Ganglin, Yan, Junqiu, Liu, Jiacong, Shen, Guimin, Luo   +5 more
openaire   +2 more sources

The role of antioxidant enzymes in photoprotection

Photosynthesis Research, 2006
The enzymatic component of the antioxidant system is discussed as one of the defensive mechanisms providing protection against excessive light absorption in plants. We present an analysis of attempts to improve stress tolerance by means of the creation of transgenic plants with elevated antioxidant enzyme activities and conclude that the effect of such
Barry A, Logan, Dmytro, Kornyeyev, Justin, Hardison, A Scott, Holaday   +3 more
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Antioxidant and redox enzymes in radioprotection

Pharmacology & Therapeutics, 1988
Abstract In summary, there are theoretically several ways by which a cell's content of DNA repair genes or other radioprotective proteins can be increased. At present the most feasible way to do so seems to be to search for repair systems, such as the adaptive repair observed in human lymphocytes, whose activity can be increased by exogenous inducing
J E, Biaglow, M E, Varnes, E R, Epp, E P, Clark   +3 more
openaire   +2 more sources

Antioxidant Enzymes in Human Tears

Journal of Ocular Pharmacology and Therapeutics, 1991
Minimally stimulated tear samples collected from human subjects were assayed for the major antioxidant enzymes: superoxide dismutase, catalase and glutathione peroxidase. No catalase or glutathione peroxidase activity was detected. However, human tear film does contain the CuZn superoxide dismutase (103 +/- 32 ng/mg soluble protein), which is ...
R K, Crouch, P, Goletz, A, Snyder, W H, Coles   +3 more
openaire   +2 more sources