Results 271 to 280 of about 542,332 (344)

Endogenous Amplification of Apoptosis via p53 Regulation using a Cascade Nanocatalytic Medicine

Advanced Science, EarlyView.
An engineered MOF nanomedicine (MAL) triggers cascade nanocatalysis in tumors, converting H2O2 and L‐Arg into cytotoxic peroxynitrite. This induces DNA damage, activates the p53 pathway, and amplifies mitochondrial apoptosis via the BAX/Bcl‐2/Caspase‐3 axis, effectively inhibiting colorectal cancer growth with high biocompatibility.
Tan Wu, Xiaoyue Xu, Dan Xu, Hui Zhang, Nan Wang, Yang Yang, Qian Chen, Shunjie Chen, Cheng Li   +8 more
wiley   +1 more source

Dietary prebiotic-stevioside modulates the growth, antioxidant enzymes, and immune response in thinlip mullets (Liza ramada) subjected to chronic cold stress. [PDF]

BMC Vet Res
Shehata AI, El Basuini MF, Elmaghraby AM, Alhoshy M, Soliman AA, Amer AA, Ibrahim NA, Habib YJ, Gewaily MS, Teiba II, Shahin SA.   +10 more
europepmc   +1 more source

Antioxidant, hypolipidemic and angiotensin converting enzyme inhibitory effects of alkaloid fraction of Hyphaene thebaica(Doum palm) on high fat-fed obese wistar rats

, 2019
Ajao Moyosore Salihu, Bilal UMAR, K.G. Hussain, R. K. Bala, Binta G. Kurfi, Mansurah A. Abdulazeez   +5 more
openalex   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

Assessing the effects of cadmium on antioxidant enzymes and histological structures in rainbow trout liver and kidney. [PDF]

Sci Rep
Taysı MR.
europepmc   +1 more source

Application of selenium nanoparticles is more effective in improving the growth, yield, antioxidant enzymes, and essential oil production of Dracocephalum kotschyi Boiss compared to sodium selenite [PDF]

Parisa Khanizadeh, Hasan Mumivand, Mohamad Reza Morshedloo   +2 more
openalex   +1 more source

Bilirubin as a Modulator of WNK1 Protein Signaling: Implications for Neuroinflammatory Diseases

Advanced Science, EarlyView.
ABSTRACT Previously regarded merely as a potentially harmful waste product of heme catabolism, bilirubin has now emerged as a pleiotropic molecule with potent antioxidant, anti‐inflammatory, and hormone‐like properties. Recent findings have revealed protective effects against cardiovascular, metabolic, autoimmune, and neoplastic diseases, as well as ...
Sri Jayanti, Libor Vítek, Silvia Gazzin, Claudio Tiribelli   +3 more
wiley   +1 more source

Oxidative damage biomarkers and antioxidant enzymes in saliva of patients with peri-implant diseases. [PDF]

Int J Implant Dent
Özkan Karasu Y, Maden O, Çanakçı CF.
europepmc   +1 more source

MORPHOLOGICAL AND FUNCTIONAL CHANGES OF ERYTHROCYTES AND ENZYMES OF THE ANTIOXIDANT SYSTEM IN MULTIPLE SCLEROSIS

І. К. Churpiy, V.A. Hryb, S. L. Popel, I. I. Liskevych, Yu. S. Kuravska, V. I. Hrynchak, L. A. Pylypiv   +6 more
openalex   +1 more source

Anti-cancer effect of lactic acid bacteria expressing antioxidant enzymes or IL-10 in a colorectal cancer mouse model

, 2016
Silvina del Carmen, Alejandra de Moreno de LeBlanc, Romina Levit, Vasco Azevedo, Philippe Langella, Luis G. Bermúdez‐Humarán, Jean Guy LeBlanc   +6 more
openalex   +2 more sources