Results 41 to 50 of about 523,877 (311)

Cu,Zn superoxide dismutase genes in Tribolium castaneum: evolution, molecular characterisation and gene expression during immune priming. [PDF]

, 2017
The production of reactive oxygen species (ROS) is a normal consequence of the aerobic cell metabolism. Despite their high and potentially detrimental reactivity with various biomolecules, the endogenous production of ROS is a vital part of physiological,
Bakiu, Rigers, Corr\ue0, Francesca, Ferro, Diana, Kevin, Ferro, Kurtz, Joachim, Santovito, Gianfranco   +5 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Signaling Toward Reactive Oxygen Species-Scavenging Enzymes in Plants

Frontiers in Plant Science, 2021
Reactive oxygen species (ROS) are signaling molecules essential for plant responses to abiotic and biotic stimuli as well as for multiple developmental processes.
Petr Dvořák, Yuliya Krasylenko, Adam Zeiner, Jozef Šamaj, Tomáš Takáč   +4 more
doaj   +1 more source

Antioxidant enzymes, presbycusis, and ethnic variability [PDF]

Otolaryngology–Head and Neck Surgery, 2010
OBJECTIVEA proposed mechanism for presbycusis is a significant increase in oxidative stress in the cochlea. The enzymes glutathione S‐transferase (GST) and N‐acetyltransferase (NAT) are two classes of antioxidant enzymes active in the cochlea. In this work, we sought to investigate the association of different polymorphisms of GSTM1, GSTT1, and NAT2 ...
Anthony, Bared, Xiaomei, Ouyang, Simon, Angeli, Li Lin, Du, Kimberly, Hoang, Denise, Yan, Xue Zhong, Liu   +6 more
openaire   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Changes in the antioxidant properties of Ocimum africanum leaves aqueous extract from the southeastern region of Nigeria after in vitro gastrointestinal digestion

International Journal of Food Properties, 2022
The potential for antioxidant compounds to be released from the original food matrix is greatly determined by bioaccessibility. Digestive enzymes have a substantial impact on the antioxidant properties of dietary items after ingestion.
Godson Oseahumen Omoike, Betty Omenebelle George, Emilia Onyinye Ugwu, Joel Okpoghono   +3 more
doaj   +1 more source

The biotechnology of higher fungi - current state and perspectives [PDF]

, 2014
This review article concisely describes methodology of biotechnological processes with the use of cultures of higher fungi, their application in bioremediation and to obtain biologically active preparations.
Turło, Jadwiga
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Effect of arsenic-phosphorus interaction on arsenic-induced oxidative stress in chickpea plants [PDF]

, 2009
Arsenic-induced oxidative stress in chickpea was investigated under glasshouse conditions in response to application of arsenic and phosphorus. Three levels of arsenic (0, 30 and 60 mg kg−1) and four levels of P (50, 100, 200, and 400 mg kg−1) were ...
A Gunes, A Mishra, A Molassiotis, AA Carbonell-Barrachina, AA Meharg, AA Meharg, AA Meharg, AA Meharg, AA Meharg, Ali Inal, AO Fayiga, Aydin Gunes, C Tu, C Tu, CI Ullrich-Eberius, CN Giannopolitis, David J. Pilbeam, DM Hodges, E Smith, EI Ochiai, EV Chuparina, FJ Peryea, H Castillo-Michel, H Gong, I Cakmak, IJ Pickering, J Hartley-Whitaker, J Ivanova, JO Nriagu, M Jain, M Srivastava, MJ Anjos, MJ Hodson, N Stoeva, N Stoeva, P Prieto, PG Smith, PV Mylona, R Mittler, R Requejo, RK Sairam, S Tu, SP Mukherjee, WE Stephens, Y Gao, Y Nakano   +45 more
core   +1 more source

Relationships among alcoholic liver disease, antioxidants, and antioxidant enzymes

World Journal of Gastroenterology, 2016
Excessive consumption of alcoholic beverages is a serious cause of liver disease worldwide. The metabolism of ethanol generates reactive oxygen species, which play a significant role in the deterioration of alcoholic liver disease (ALD). Antioxidant phytochemicals, such as polyphenols, regulate the expression of ALD-associated proteins and peptides ...
Kyu-Ho, Han, Naoto, Hashimoto, Michihiro, Fukushima   +2 more
openaire   +2 more sources