Results 81 to 90 of about 542,332 (344)
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah +8 more
wiley +1 more source
The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome
The Scientific World Journal, 2013 The purpose of this study was to investigate the levels of coenzyme Q10 and vitamin E and the antioxidant status in subjects with metabolic syndrome (MS). Subjects with MS (n=72) were included according to the criteria for MS.
Chi-Hua Yen +5 more
doaj +1 more source
Copper-caused oxidative stress triggers the activation of antioxidant enzymes via ZmMPK3 in maize leaves. [PDF]
PLoS ONE, 2018 Copper (Cu) is a necessary trace element participated in many physiological processes in plants. But excessive Cu2+ is toxic, which can activate intracellular signals that lead to cellular damage. The mitogen-activated protein kinase (MAPK) cascade is at
Jianxia Liu +3 more
doaj +1 more source
Role of antioxidant supplementation and exercise regimen in handling oxidative stress from natural PM2.5 exposure due to boreal forest fire [PDF]
, 2019 Thesis (M.S.) University of Alaska Fairbanks, 2019Particulate matter 2.5 (PM2.5) exposure induces oxidative stress that causes many negative health outcomes such as cancer, cardiovascular disease and neurodegenerative disease. Research shows that dietary
Witkop, Jacob J.
core
Biologia Plantarum, 2012 Glucose-6-phosphate dehydrogenase (G6PDH) has been implicated in supplying reduced nicotine amide cofactors for biochemical reactions and in modulating the redox state of cells.
H. Gong +5 more
doaj +1 more source
Thermostability of antioxidant enzymes in tissues of Scots pine in heat shock conditions [PDF]
Сибирский лесной журнал, 2017 Samples of needles from the middle part of the crown and cambial zone scrapings, which includes cambium cells and nonlignified xylem cells from five stems of 15 years old Scots pine Pinus sylvestris L.
N. E. Sudachkova +3 more
doaj +1 more source
Alterations in oxidative, inflammatory and apoptotic events in short-lived and long-lived mice testes [PDF]
, 2016 Aged testes undergo profound histological and morphological alterations leading to a reduced functionality. Here, we investigated whether variations in longevity affect the development of local inflammatory processes, the oxidative state and the ...
Bartke, Andrzej +7 more
core +2 more sources