Results 81 to 90 of about 523,877 (311)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Mechanistic insights into the impact of Maillard reaction products on endogenous antioxidant systems in fish muscle

Future Foods
The Maillard reaction products (MRPs) inhibit fish lipid oxidation; however, whether they act with the endogenous antioxidants in fish is unclear.
Jiarong Cao, Haixia Yan, Bo Ye, Yixiao Shen, Ling Liu   +4 more
doaj   +1 more source

The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome

The Scientific World Journal, 2013
The purpose of this study was to investigate the levels of coenzyme Q10 and vitamin E and the antioxidant status in subjects with metabolic syndrome (MS). Subjects with MS (n=72) were included according to the criteria for MS.
Chi-Hua Yen, Nae-Cherng Yang, Bor-Jen Lee, Jui-Yuan Lin, Simon Hsia, Ping-Ting Lin   +5 more
doaj   +1 more source

Long term effect of curcumin in restoration of tumour suppressor p53 and phase-II antioxidant enzymes via activation of Nrf2 signalling and modulation of inflammation in prevention of cancer. [PDF]

PLoS ONE, 2015
Inhibition of carcinogenesis may be a consequence of attenuation of oxidative stress via activation of antioxidant defence system, restoration and stabilization of tumour suppressor proteins along with modulation of inflammatory mediators.
Laxmidhar Das, Manjula Vinayak
doaj   +1 more source

In vitro ion chelating, antioxidative mechanism of extracts from fruits and barks of tetrapleura tetraptera and their protective effects against fenton mediated toxicity of metal ions on liver homogenates [PDF]

, 2015
The aim of the present study was to investigate the antioxidant activity and protective potential of T. tetraptera extracts against ion toxicity. The antioxidant activity of the extracts was investigated spectrophotometrically against several radicals (1,
Biapa, P. C. N., Bravi, Marco, Moukette, B. M., Ngogang, J. Y., Njimou, J. R., Pieme, C. A., Stoller, Marco   +6 more
core   +3 more sources

Serum Uric Acid Levels in Older Adults: Associations With Clinical Outcomes and Implications for Reference Intervals in Those Aged 70 Years and Over

Arthritis Care &Research, EarlyView.
Objective Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged ≥70 years old.
Amanda J. Rickard, Cammie Tran, Hans G. Schneider, Flavia M. Cicuttini, Anita E. Wluka, Ego Seeman, Johannes T. Neumann, Md Nazmul Karim, Zhen Zhou, Sultana Monira Hussain, David P. Q. Clark, Daniel Clayton‐Chubb, Andrew M. Tonkin, Lawrence J. Beilin, Robyn L. Woods, John J. McNeil   +15 more
wiley   +1 more source

Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes [PDF]

, 2017
Cardiovascular diseases are the main cause of mortality and morbidity in the world. Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart failure through oxidative and nitrosative stresses which cause cardiomyocytes ...
Bei, Roberto, Benvenuto, Monica, Bergante, Sonia, Giganti, Maria Gabriella, Manzari, Vittorio, Masuelli, Laura, Mattera, Rosanna, Modesti, Andrea, Pluchinotta, Francesca Romana, Tettamanti, Guido, Tresoldi, Ilaria   +10 more
core   +2 more sources

[Antioxidant enzymes in acute cerebral infarction].

Neurologia (Barcelona, Spain), 2004
Oxidative modification of DNA, protein and lipids by reactive oxygen peroxides plays an important role in acute cerebral infarction. The biological antioxidant defence system against oxidative stress is an integrated array of enzymes such as superoxide dismutase (SOD), catalase (CAT) and glutathion peroxidase (GPx). The purpose of this work was: 1.
Casado Moragón, Ángela, Torre, R. de la, López-Fernández, M.E., Gill, P., Egido, J.A.   +4 more
openaire   +3 more sources

Marked Long‐term Improvement in Lung Function in Melanoma Differentiation‐associated Protein 5 (MDA5) Antibody Positive Dermatomyositis Patients: Experience of a Single Center Longitudinal Cohort in North America

Arthritis Care &Research, Accepted Article.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation‐associated gene 5 antibody (MDA5 ab) associated dermatomyositis (DM). Methods Thirty patients with MDA5 ab DM were identified in a single center longitudinal cohort of 352 patients with ...
Jenice X Cheah, Sangmee S Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Effect of 8 Weeks of Incremental Endurance Training on Antioxidant Enzymes and Total Antioxidant Status of Cardiac Tissue in Experimental Diabetic Rats

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020
Introduction: Evidence suggests increased oxidative stress and improved total antioxidant status resulting from regular exercise in the heart tissue of diabetic patients.
Eftekhar Mohammadi, Fatemeh Nikseresht
doaj