Results 71 to 80 of about 345,363 (312)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Glaucoma and Antioxidant Status

, 2014
Glaucoma, one of the leading causes of irreversible blindness in the world, is defined as a slowly progressive optic neuropathy characterized by retinal nerve fiber and visual field loss. Although increased intraocular pressure is the major risk factor for glaucoma, other risk factors include advanced age, genetic predisposition, family history, gender,
Tosun, Mehmet, Yağcı, Ramazan, Erdurmuş, M.   +2 more
openaire   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Antioxidant status associated with inflammation in sarcoidosis: A potential role for antioxidants [PDF]

Respiratory Medicine, 2009
Enhanced production of reactive oxygen species (ROS), capable of reducing endogenous defense levels and enhancing inflammation, is suggested to play a role in sarcoidosis. Antioxidant supplementation might offer protection against such ROS-mediated damage. A promising candidate for antioxidant supplementation is the flavonoid quercetin.To determine the
Boots, A.W., Drent, M., Swennen, E.L., Moonen, H.J., Bast, A., Haenen, G.R.   +5 more
openaire   +3 more sources

Processed meat consumption and lung function: modification by antioxidants and smoking [PDF]

, 2014
Unhealthy dietary patterns are associated with poorer lung function. It is not known whether this is due to low consumption of antioxidant-rich fruit and vegetables, or is a consequence of higher intakes of harmful dietary constituents such as processed ...
Okubo, H., Syddall, H.E., Aihie Sayer, A., Sayer, AA, Shaheen, S.O., Grp, HCS, Cooper, C., Ntani, G, Jameson, KA, Robinson, SM, Dennison, E.M., Dennison, EM, Cooper, Cyrus, Cooper, C, Shaheen, SO, Syddall, HE, Okubo, H, Robinson, S.M., Ntani, G.   +18 more
core   +1 more source

Ginger (Zingiber officinale) Root Capsules Enhance Analgesic and Antioxidant Efficacy of Diclofenac Sodium in Experimental Acute Inflammation

, 2023
Our study aimed to evaluate the analgesic and antioxidant effects of ginger (Zingiber officinale) root capsule extract (GRCE) in addition to diclofenac (D) sodium treatment in carrageenan-induced acute inflammation (AI).
Ioana Corina Bocșan, Ioana Boarescu, Dan Gheban, Raluca Maria Pop, Adriana Elena Bulboacă, Anca Dana Buzoianu, Paul-Mihai Boarescu, Sorana D. Bolboacă   +7 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

The lignans 7-hydroxymatairesinol application in adjuvant therapy of gynecological diseases [PDF]

Гинекология, 2018
The antioxidant effects of lignan - 7-hydroxymatiresinol as complementary therapy for gynecological diseases Relevance. The work is devoted to the study of the antioxidant effect of lignan - 7-hydroxymatairezinol in various gynecological diseases ...
M V Poluektova, L S Mkrtchyan, T V Tchirkova, O A Vorobyova, L I Krikunova   +4 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Status of the brain antioxidant system at different growing periods after prenatal stress and N -acetyl cysteine administration

, 2017
Prenatal stress-induced neurobehavioral deficits observed in offspring are multifactorial, including oxidative stress in the developing brain. The time by which the developing brain acquires self-defense against oxidative stress is not clear.
Sampath Madhyastha, Anoop Kishore, Liegelin Kavitha Bernhardt, Lakshminarayana Bairy   +3 more
core   +1 more source