Results 91 to 100 of about 4,162,843 (311)

Blood cells as functional markers of antioxidant vitamin status

open access: yes, 2006
Antioxidants have shown beneficial effects in several biological systems, in which they were able to prevent oxidative stress-associated damage. Vitamins C and E are key antioxidants in man. Dietary intake cannot accurately reflect plasma vitamin levels.
Josep Tur-Marí   +2 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Dietary supplementation of Eucalyptus leaves enhances eggshell quality and immune response in two varieties of Japanese quails under tropical condition

open access: yesPoultry Science, 2020
The effect of dietary supplementation of Eucalyptus leaves (EL) powder on productive performance and immune response in 2 varieties of Japanese quail was investigated. A total of 180 twelve-week-old laying Japanese quails from 2 color varieties (gray and
M.M. Fathi   +4 more
doaj   +1 more source

Status of the brain antioxidant system at different growing periods after prenatal stress and N -acetyl cysteine administration

open access: yes, 2017
Prenatal stress-induced neurobehavioral deficits observed in offspring are multifactorial, including oxidative stress in the developing brain. The time by which the developing brain acquires self-defense against oxidative stress is not clear.
Sampath Madhyastha   +3 more
core   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

An automated panel for assessing pro-oxidant and antioxidant status in human serum

open access: yes, 2017
Background: The implied role of reactive oxygen species in diabetes, cardiovascular disease and some forms of cancer suggests that the measurement of pro-oxidant and antioxidant biomarkers may be a useful addition to current routine tests.
Ferrier, C., Reed, S.C., Elliott, B.
core  

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Quercetin: a natural remedy against high-fat diet-induced liver steatosis in Oncorhynchus mykiss

open access: yesFrontiers in Marine Science
IntroductionThis study investigated the effects of a high-fat diet (HFD) on hepatic steatosis and the protective role of quercetin (3,3′,4′,5,7-pentahydroxyflavon) in juvenile female rainbow trout (Oncorhynchus mykiss).MethodsA total of 270 fish were ...
Özay Köse
doaj   +1 more source

Antioxidant supplementation enhances erythrocyte antioxidant status and attenuates cyclosporine-induced vascular dysfunction

open access: yes, 2006
The aim of this study was to determine the effects of dietary antioxidant supplementation with a-tocopherol and a-lipoic acid on cyclosporine induced alterations to erythrocyte and plasma redox balance, and cyclosporine-induced endothelial and smooth ...
Lexis, Louise.   +19 more
core   +1 more source

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