Results 81 to 90 of about 4,162,843 (311)

Extract from Silybum marianum as a nutraceutical: a double-blind placebo-controlled study in healthy young men

Czech Journal of Food Sciences, 2001
In a randomized, double-blind, placebo-controlled study, the effect of an extract from Silybum marianum seeds (ESM, milk thistle extract) on lipid and liver parameters and the antioxidant capacity of serum was investigated in 29 healthy men aged 18-32 ...
V. Šimánek, N. Škottová, J. Bartek, J. Psotová, P. Kosina, L. Balejová, J. Ulrichová   +6 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Antioxidant Status in Children with Neurogenic Bladder

Children
Background: Pediatric neurogenic bladder (NB), often resulting from myelomeningocele, impairs bladder function due to disrupted neural control and is worsened by urinary retention, recurrent urinary tract infections, the absence of voluntary voiding, and additional sequelae of myelomeningocele, such as motor impairments, delayed colonic transit, and ...
Joanna Bagińska-Chyży, Agata Korzeniecka-Kozerska   +1 more
openaire   +3 more sources

A Chinese Herbal Formulation, Xiao-Er-An-Shen Decoction, Attenuates Tourette Syndrome, Possibly by Reversing Abnormal Changes in Neurotransmitter Levels and Enhancing Antioxidant Status in Mouse Brain

Frontiers in Pharmacology, 2019
Xiao-Er-An-Shen Decoction (XEASD) has been used clinically for the treatment of Tourette syndrome (TS) in children for more than 20 years in mainland China.
Jihang Chen, Pou Kuan Leong, Hoi Yan Leung, Wing Man Chan, Zhonggui Li, Jingyu Qiu, Kam Ming Ko, Jianping Chen   +7 more
doaj   +1 more source

Total antioxidant status in plasma.

, 2012
Total antioxidant status (TAS) in plasma of TP53 p.R337H carriers (n = 16) and non-carriers (n = 16).
Pierre Hainaut (15065), Cristina B. O. Netto (128243), Gabriel S. Macedo (128234), Camila S.Vanzin (128248), Carmen Regla Vargas (128252), Juliana Giacomazzi (128241), Fábio Klamt (128257), Leonardo Lisbôa da Motta (128238), Patricia Ashton-Prolla (128262), Vanusa Manfredini (128245)   +9 more
core   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Oxidant and Non-enzymatic Antioxidant Status in Measles [PDF]

Journal of Tropical Pediatrics, 2006
Measles is a highly contagious viral disease of childhood associated with serious complications and significant morbidity and mortality. In the present study, antioxidant and oxidant status was investigated in children with measles. Our aim was to evaluate the possible changes in non-enzymatic antioxidant levels and their relationship to the oxidative ...
Cemek, Mustafa, Dede, Semiha, Bayiroglu, Fahri, Caksen, Hueseyin, Cemek, Fatma, Mert, Nihat   +5 more
openaire   +4 more sources

Effects of dietary fiber on the antioxidant capacity, immune status, and antioxidant-relative signaling molecular gene expression in rat organs

, 2017
This study was conducted to evaluate the effects of different fibers, such as dietary pea, sweet potato, and wheat bran fibers, on the antioxidant capacity, immune status, and antioxidant-related signaling molecules of rat organs.
Caimei Wu, Xianjian Wu, Wei Cao, Guangmang Liu, Jiayong Tang, Gang Jia, Tingting Fang, Hua Zhao, Jing Wang, Xiaoling Chen   +9 more
core   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Effect of Turmeric and Carrot Seed Extracts on Serum Liver Biomarkers and Hepatic Lipid Peroxidation, Antioxidant Enzymes and Total Antioxidant Status in Rats [PDF]

Introduction: Pathogenic role of free radicals are well known in various metabolic diseases. They originate from internal and external sources of body.
رضایی مقدم, عادل, مهاجری, داریوش, شهیدی, مریم السادات, رفیعی, بهنام, مأذنی, محمد, اظهری, اصغر, دیزجی, رعنا, یگانه زاد, مهدی   +7 more
core