Species-Specific Effects of Humic Substances and Mycorrhiza on Antioxidant Defense and Metal Stress Tolerance in <i>Cannabis sativa</i>, <i>Sorghum sudanense × bicolor</i>, and <i>Miscanthus × giganteus</i> Under Field Conditions. [PDF]
Jaros-Tsoj K +7 more
europepmc +1 more source
ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan +3 more
wiley +1 more source
Cardiovascular Benefits of <i>Salvia miltiorrhiza</i> (Danshen) Supplementation: Bioactive Constituents, Mechanisms, Clinical Evidence and Implications for Nutritional Care. [PDF]
Vikal A +6 more
europepmc +1 more source
Microalgae‐derived bioactive compounds exhibit strong antioxidant and antimicrobial properties and can be incorporated into edible coatings to enhance food quality and shelf life. These materials offer sustainable, biodegradable alternatives to conventional packaging, with promising potential for future scalable food applications.
Madhu Gaidher +9 more
wiley +1 more source
Differential Sensitivity of Endocrine and Non-Endocrine Tissues to Cadmium-Induced Lipid Peroxidation and the Protective Role of Melatonin. [PDF]
Gładysz AK +2 more
europepmc +1 more source
ABSTRACT Background Distal symmetrical polyneuropathy (DSPN) is a common complication of type 1 diabetes (T1D), yet validated biomarkers for early detection or prognosis are lacking. Metabolic disturbances driven by chronic hyperglycemia and dyslipidemia contribute to DSPN development and progression.
Tik Muk +18 more
wiley +1 more source
Metabolic Flux Analysis Reveals Entner-Doudoroff Pathway Dominance in Heterotrophic Deep-Sea Bacterial Isolates. [PDF]
Yang Y +7 more
europepmc +1 more source
4‐Octyl itaconate (4‐OI) attenuates age‐induced parotid gland dysfunction through the suppression of fibrosis and lipid deposition by AMPKα/PPARα and the inhibition of oxidative stress via the AMPKα/Nrf2 signaling pathway. 4‐OI activates AMPKα, which in turn stimulates both the PPARα and Nrf2 pathways. Activation of PPARα enhances FAO and reduces lipid
Yun Chen +6 more
wiley +1 more source
Pachymic acid alleviates hepatic lipid accumulation and oxidative stress in MASLD via regulation of the Keap1-Nrf2-HO-1 signaling axis. [PDF]
Li M, Wang Z, Zhai H, Li J, Ma J, Qiu B.
europepmc +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source

