Results 231 to 240 of about 948,009 (300)

A Retrospective Controlled Study on the Effects of Four-Limb Linkage Training on Clinical Efficacy and Antioxidative Mechanisms in Patients with Chronic Obstructive Pulmonary Disease. [PDF]

Int J Chron Obstruct Pulmon Dis
Liu X, Chen L, Wei Z, Jiang J, Yu Y, Wang Z.   +5 more
europepmc   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, Volume 13, Issue 56, 9 October 2026.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Research progress on the regulation of microglia and astrocyte functions by protein lactylation in cerebral ischemia-reperfusion injury: A review. [PDF]

Medicine (Baltimore)
Song HH, Jiang XC.
europepmc   +1 more source

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, Volume 13, Issue 55, 5 October 2026.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source

Warm Acclimation Modulates the Physiological Responses of Young <i>Saccharina japonica</i> to Marine Heatwaves. [PDF]

Biology (Basel)
Xue Y, Wang Y, Xu D, Li X, Chen X, Chu Y, Huang X.   +6 more
europepmc   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, Volume 13, Issue 56, 9 October 2026.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Total Antioxidant Capacity and Total Oxidative Capacity in Multi-Modal Opioid-Based Therapy for Non-Cancer Pain: Analysis of Redox Status. [PDF]

Curr Issues Mol Biol
Kosciuczuk U, Jakubow P, Talalaj M, Grabowska K.   +3 more
europepmc   +1 more source

Carbon Dots With Concurrently Tunable Photoluminescence and Nanozyme Activity for Agricultural Stress Resistance: A Carbonization Degree‐Mediated Strategy

Aggregate, Volume 7, Issue 10, October 2026.
Carbonization degree is established as a unified structural parameter that synergistically governs the photoluminescence and SOD‐like activity of CDs. Progressive carbonization generates sp2‐conjugated domains where edge‐site carbonyl groups act as catalytic sites for SOD‐like activity.
Yunge Tang, Yue Zhang, Xin Peng, Xinyuan Wang, Pengpeng Wang, Kang Sun, Lei Han, Siyu Lu, Xiaokai Xu   +8 more
wiley   +1 more source

Natural antioxidant products and nanomaterial-based delivery systems for the amelioration of diabetic retinopathy: mechanisms, applications, and translational perspectives. [PDF]

Front Immunol
Tao Y, Zha B, Zhang F, Du W, Lin S, Gao X, Tang W, Gao J, Jiang Z.   +8 more
europepmc   +1 more source