Results 241 to 250 of about 948,009 (300)

Dodonaea viscosa in Breast Cancer: Phytochemistry, Anticancer Mechanisms, and Emerging Immunotherapeutic and Translational Perspectives

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Breast cancer remains a leading cause of cancer‐related mortality among women worldwide, with treatment resistance, disease heterogeneity, and therapy‐associated toxicities limiting clinical outcomes. Its major clinically relevant subtypes, including oestrogen receptor‐positive (ER+), human epidermal growth factor receptor 2‐positive (HER2 ...
Nireshini Reddy, Catherine H. Kaschula, Nokwanda P. Makunga, Willem Jacobus Perold, Sanjeev Rambharose, Anna‐Mart Engelbrecht   +5 more
wiley   +1 more source

Phytochemical Fingerprinting of Sanchezia nobilis Hook. F. Leaf Extract and Evaluation of Anxiolytic, Cytotoxic, and Antioxidant Activities In Vivo, In Vitro, and In Silico

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
GC‐MS fingerprinting demonstrated that ethanolic leaf extract of Sanchezia nobilis (SNE) many phytochemicals out of which aniline and isoquinoline showed potential binding affinity to alpha1GABAA receptor responsible for anxiolytic effects. In vitro studies confirmed antioxidant effects of SNE.
Progga Paramita Paul, Musfiqur Rahman Sakib, Pritam Kundu, Dabashis Chakraborty, Tasnim Fatema, Shahriar Hossen, Ahsan Abid, Trina Mitra, Manik Chandra Shill, Utpal Kumar Karmakar   +9 more
wiley   +1 more source

Translational Feasibility of Curcumin for Treatment of Alzheimer's Disease: A Critical Appraisal of Clinical Challenges. [PDF]

Antioxidants (Basel)
Virk JP, Fernando MG, Asih PR, Martins RN.   +3 more
europepmc   +1 more source

Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella, Khai‐Lin Hew, Yeun‐Mun Choo   +2 more
wiley   +1 more source

CoCl₂-induced alterations in antioxidative and inflammatory marker expression in an siRNA-based in vitro model of aniridia-associated limbal epithelial dysfunction. [PDF]

BMC Ophthalmol
Hsu SL, Szentmáry N, Fries FN, Li Z, Chai N, Seitz B, Amini M, Suiwal S, Stachon T.   +8 more
europepmc   +1 more source

Exploring the Neuropharmacological Potential of Ligustrum sinense Relevant to Parkinson's Disease: In Vivo and In Silico Study

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ligustrum sinense (L. sinense) leaf extract exhibited moderate antioxidant activity (DPPH IC50 = 73.56 ± 2.18 µg/mL) and was evaluated for neuropharmacological effects at 200 and 400 mg/kg using elevated plus maze, open‐field, hole‐cross, and hole‐board tests.
Sowmitro Das, S. M. Istiaque Hamim, Md Nazmul Hasan Zilani, Kazi Sneha Chhando, Puza Das, Md Ridoy Hossain, Md. Imtiaz, Jebin Tasmin, Roney Miah, Md. Nazmul Hasan   +9 more
wiley   +1 more source

Oxidative and nitrosative damage in multiple sclerosis. [PDF]

Curr Opin Neurol
Prozorovski T, Meuth SG, Hartung HP, Berndt C.   +3 more
europepmc   +1 more source

Integrating Structural Characterization, Network Pharmacology, and Experimental Validation Reveals the Anti‐Liver Aging Mechanism of Acorus tatarinowii Polysaccharides

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
ATP is extracted and structurally characterized. Network pharmacology, WGCNA and machine learning identify TLR4 and Nrf2 as core targets. In D‐gal‐induced aging rats, ATP relieves hepatic atrophy and steatosis, suppresses hepatic TLR4, NF‐κB, and HO‐1 expression, and up‑regulates Nrf2 expression, showing its promising potential for counteracting ...
Yikuan Du, Jiahui Li, Yuting Lin, Jiawen Luo, Weien Zhang, Feng Chen, Zhonghan Liang, Jiaxin Zhu, Jiaqi Li, Chenyue Yuan, Yidian Liu, Xuan Liu, Yang Zhang, Qiaohong Zhong, Yanling Jiang, Songsong Yang, Chunling Ma, Zhi Chen, Chun Yang   +18 more
wiley   +1 more source

From animal models to metabolic interventions: Lessons from the Wobbler mouse. [PDF]

Neural Regen Res
Matschke V.
europepmc   +1 more source

Phytochemistry, Pharmacological Potential, and Future Prospects of Abietane‐Type Diterpenoids From Salvia rosmarinus

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
The review delves into the findings on abietane diterpenes from Salvia rosmarinus. It comprises the phytochemistry, biological activities, biosynthesis, degradation studies, semisynthesis, and pharmacokinetic studies of these compounds. The potential of these compounds for future development has also been highlighted.
Rida Siddiqui, Vipin Singh, Kapil Dev
wiley   +1 more source