Results 91 to 100 of about 22,500 (289)

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

ChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges, Priscilla Ramos Freitas, Isaac Moura Araújo, Ray Silva de Almeida, Igor José dos Santos Nascimento, João Xavier de Araújo‐Júnior, Edeildo Ferreira da Silva‐Júnior, Thiago Mendonça de Aquino, Francisco Jaime Bezerra Mendonça Junior, Emmanuel Silva Marinho, Hélcio Silva dos Santos, Radosław Kowalski, Grażyna Kowalska, Henrique Douglas Melo Coutinho, Saulo Relison Tintino, Ana Carolina Justino de Araújo   +15 more
wiley   +1 more source

Ruthenium‐Catalyzed CH Alkenylation of Trypanocidal Naphthoquinones: A Mechanistic Benchmarking Study

ChemistryOpen, EarlyView.
Computational roadmap to click‐ready quinones. Quantum chemical analysis reveals how substituents modulate the reactivity of trypanocidal naphthoquinones in Ru‐catalyzed CH alkenylation, guiding the design of sulfonyl‐fluoride scaffolds for next‐generation antiparasitic agents.
Esther R. S. Paz, Cauê P. Souza, Joyce C. De Oliveira, Renata G. Almeida, Chonny Herrera‐Acevedo, Sulaiman Lakoh, Guilherme A. M. Jardim, Eufrânio N. da Silva Júnior, Felipe Fantuzzi   +8 more
wiley   +1 more source

Insights into Chagas treatment based on the potential of bacteriocin AS-48

International Journal for Parasitology: Drugs and Drug Resistance, 2019
Chagas disease caused by the protozoan parasite Trypanosoma cruzi represents a significant public health problem in Latin America, affecting around 8 million cases worldwide.
Rubén Martín-Escolano, Rubén Cebrián, Javier Martín-Escolano, Maria J. Rosales, Mercedes Maqueda, Manuel Sánchez-Moreno, Clotilde Marín   +6 more
doaj   +1 more source

Demystifying fungal systematics: A gateway to fungal literacy and societal/ecological relevance through familiar species

PLANTS, PEOPLE, PLANET, EarlyView.
Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana, Francis Martin, Rasmus Kjøller, Toby Spribille, Garima Singh   +4 more
wiley   +1 more source

Perspective on the Genetic Response to Antiparasitics: A Review Article [PDF]

, 2017
Background: Drugs’ pharmacokinetics and pharmacodynamics can be af- fected by diverse genetic variations, within which simple nucleotide poly- morphisms (SNPs) are the most common.
ALARCON VALDES, PATRICIA, ALARCON VALDES, PATRICIA, ORTIZ REYNOSO, MARIANA, ORTIZ REYNOSO, MARIANA, SANTILLAN BENITEZ, JONNATHAN GUADALUPE, SANTILLAN BENITEZ, JONNATHAN GUADALUPE   +5 more
core   +1 more source

Effects of the repeated distribution of sainfoin hay on the resistance and the resilience of goats naturally infected with gastrointestinal nematodes [PDF]

, 2005
Due to the high prevalence of anthelmintic resistance in goats, the need to explore novel approaches to control nematodes and to reduce the exclusive reliance on chemotherapy is strongly demanded in this host species.
F., De La Farge, F., Prevot, H., Hoste, Ph., Dorchies, V., Paolini   +4 more
core   +1 more source

Biodegradable Sodium Alginate Films Incorporated With Jateorhiza palmata (Lam.) Miers Extract for Active Food Packaging

Packaging Technology and Science, EarlyView.
Development of biodegradable sodium alginate films incorporated with J. palmata root extracts showing enhanced antioxidant and functional properties for active food packaging applications. ABSTRACT Biodegradable packaging helps reduce environmental impact by decomposing naturally and preventing plastic accumulation in ecosystems.
Carlos Augusto Badillo Almeira, Suiane Savazzi, Raul Remor Dalsasso, Alcilene Rodrigues Monteiro, Alessandro de Oliveira Rios   +4 more
wiley   +1 more source

Cyclic Oligosaccharides as Active Drugs, an Updated Review

Pharmaceuticals, 2020
There have been many reviews of the cyclic oligosaccharide cyclodextrin (CD) and CD-based materials used for drug delivery, but the capacity of CDs to complex different agents and their own intrinsic properties suggest they might also be considered for ...
Adrián Matencio, Fabrizio Caldera, Claudio Cecone, José Manuel López-Nicolás, Francesco Trotta   +4 more
doaj   +1 more source

‘Knowledge, attitudes and practices’ survey of Austrian veterinarians' antibiotic use in clinical practice

Veterinary Record, EarlyView.
Abstract Background Antimicrobial resistance (AMR) is a critical global health issue, with antimicrobial use (AMU) in veterinary medicine playing a relevant role in its emergence. This study aimed to evaluate the knowledge, attitudes and practices of Austrian veterinarians regarding AMU and AMR.
Clair L. Firth, Patricia Mayer, Annemarie Käsbohrer, Tanja Tripolt, Klemens Fuchs   +4 more
wiley   +1 more source

Antiparasitic and antimicrobial activity of Ipomoea palmata against Toxoplasma gondii and Staphylococcus aureus: correlation with major phenolics identified by HPLC

Artificial Cells, Nanomedicine, and Biotechnology
Toxoplasma gondii, a protozoan parasite found in water sources, causes toxoplasmosis, with no current protocols for inactivating its oocysts in water.
Amira Mira, Tariq M. Aljarba, Fatma M. Abdel Bar, Rehab Ahmed, Walaa A. Negm, Engy Elekhnawy, Hosam M. El-Seadawy, Eman A. Elmorsy, Salwa S. Younis   +8 more
doaj   +1 more source