Results 1 to 10 of about 49,496 (199)

Sustained Release Antiparkinson Agents: Controlled Release Levodopa [PDF]

open access: bronzeCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1992
ABSTRACT:The rationale for sustained release oral levodopa preparations is to deliver levodopa in the areas of maximal intestinal absorption in a slow and predictable way, leading to stable plasma levodopa levels and brain dopamine levels, therefore resulting in a lengthened duration of action.
Serge Gauthier, Donna Amyot
  +6 more sources

Anticonvulsant Activity of Antiparkinsonism Agents

open access: closedExperimental Biology and Medicine, 1968
SummaryThe anticonvulsant activity of synthetic antiparkinsonism agents has been studied in mice with experimental seizures and in children with myoclonic spasms refractory to conventional medications. Procyclidine and trihexyphenidyl protected mice from maximal electroshock seizures.
J Gordon Millichap   +2 more
openaire   +4 more sources

Association between Parkinson’s disease and cardiovascular disease mortality: a prospective population-based study from NHANES [PDF]

open access: yesLipids in Health and Disease
Background and aim Conflicting results have been reported on the association between Parkinson's disease (PD) and cardiovascular disease (CVD) mortality in different populations.
Li Ke   +3 more
doaj   +2 more sources

Characteristic action of BAM-1110, a new antiparkinson agent, on dopamine receptors

open access: goldJapanese Journal of Pharmacology, 1997
Mitsuaki Nagasaka   +3 more
openaire   +3 more sources

Validation of 19-items wearing-off (WOQ-19) questionnaire to Portuguese [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 2020
Background: The treatment of Parkinson disease with dopaminergic therapy improves functionality and quality of life. However, as the disease progresses, the wearing-off phenomenon develops.
Carlos Eduardo MANTESE   +3 more
doaj   +1 more source

Guidelines for Parkinson’s disease treatment: consensus from the Movement Disorders Scientific Department of the Brazilian Academy of Neurology - motor symptoms

open access: yesArquivos de Neuro-Psiquiatria, 2022
The treatment of Parkinson's disease (PD) is challenging, especially since it is considered highly individualized. The Brazilian Academy of Neurology has recognized the need to disseminate knowledge about the management of PD treatment, adapting the best
Roberta Arb Saba   +21 more
doaj   +1 more source

Pharmacological evaluation of BAM-1110, a novel dopamine receptor agonist, as an antiparkinson agent.

open access: goldJapanese Journal of Pharmacology, 1994
Mitsuaki Nagasaka   +3 more
openaire   +3 more sources

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